arXiv AI

Explainable Ensemble-Based Machine Learning Models for Detecting the Presence of Cirrhosis in Hepatitis C Patients

arXiv:2606. 26561v1 Announce Type: new Abstract: Hepatitis C is a liver infection caused by a virus, which results in mild to severe inflammation of the liver.

arXiv Machine Learning
4d ago

Does Machine Learning Outperform Traditional Fibrosis Scores in Predicting Liver Cirrhosis Risk? A Longitudinal EHR-Based Study

arXiv:2601.00175v3 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using...

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv Machine Learning
Jun 2

Early Prediction of Liver Cirrhosis Up to Two Years in Advance: A Machine Learning Study Benchmarking Against the FIB-4 and APRI Scores

arXiv:2601. 00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores.

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv AI
Sep 15

Potential of Artificial Intelligence Algorithms for Identification of Relevant Diagnostic and Prognostic Biomarkers of Early-Stage Liver Cancer

This study investigates deep learning and explainable AI methods to diagnose hepatocellular carcinoma (HCC) and identify diagnostic and prognostic biomarkers across five disease stages using a transcriptomic dataset built via semi‑supervised learning. The best model used 15 genes selected by SelectKBest, achieving 90.74% accuracy, while a 20‑gene model had the lowest loss of 0.3187. SHAP‑based XAI highlighted DNAJB14 as the most influential gene, and functional validation showed that inhibiting DNAJB14 reverses key malignant traits of HCC cells.

By Ali Bou Nassif, Darko Castven, Manar Abu Talib, Jibran Sualeh Muhammad, Ahmed Ammar Kubba, Jens Marquardt, Abdalla Sayed Ali
arXiv AI
Sep 7

Ultrasound-Based Prediction of Cirrhosis Decompensation Using Large-Scale Computer Vision Models

The paper introduces an imaging-based method that uses large-scale computer vision models to analyze routine abdominal ultrasound images for predicting cirrhosis decompensation. It extracts predictive features beyond traditional laboratory risk scores, offering a non-invasive, low-cost, and scalable approach for early risk stratification. The framework combines automated ultrasound processing with modern deep learning to identify high-risk patients before clinical deterioration occurs.

By Guangyi Zhang, Peiyun Ni, Eugene Cheah, Rajat Chandra, Peng Guo, Raymond T. Chung, Anthony E. Samir
arXiv Computer Vision
Aug 26

EMFE: A lightweight, explainable machine learning framework for malaria cell classification

EMFE (Efficient Mathematical Feature Extraction) is a lightweight, explainable machine‑learning framework that classifies single red‑blood‑cell images as parasitized or uninfected using five engineered features: Gray World color normalization, adaptive green‑channel thresholding, morphological spot detection, and classical classifiers. On the NIH LHNCBC malaria dataset (27,558 images from 200 patients), a tuned Random Forest achieved 94.6% pooled out‑of‑fold accuracy, 94.3% on a 40‑patient holdout, and outperformed deep‑learning baselines in an accuracy‑efficiency trade‑off. Ablation studies, synthetic perturbations, and explainability analyses identified spot saturation as the dominant discriminative feature and quantified the framework’s failure modes and patient‑level performance.

By Md Abdullah Al Kafi, Walayat Hussain, Mousumi Karmakar, Sumit Kumar Banshal, Ahmed Al Marouf
arXiv AI
Aug 26

Ensemble of Convolutional Neural Networks for StrokePrediction: Towards Improved Diagnostic Accuracy

The paper presents an intelligent system that predicts stroke risk using eleven clinical features and evaluates seven supervised machine learning algorithms. Ensemble methods—Random Forest, Stacking Classifier, and Bagging Classifier—achieved the highest accuracies, reaching 99.52%, while other models such as KNN, TabNet, and a custom feedforward network also performed well. The study demonstrates that ensemble approaches are particularly effective for stroke classification tasks.

By Md Shahriar Sajid