Hepatitis C is a liver infection caused by a virus, which results in mild to severe inflammation of the liver. Over many years, hepatitis C gradually damages the liver, often leading to permanent scarring, known as cirrhosis.
arXiv:2601.00175v3 Announce Type: replace
Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using...
By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv:2601. 00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores.
By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
This study investigates deep learning and explainable AI methods to diagnose hepatocellular carcinoma (HCC) and identify diagnostic and prognostic biomarkers across five disease stages using a transcriptomic dataset built via semi‑supervised learning. The best model used 15 genes selected by SelectKBest, achieving 90.74% accuracy, while a 20‑gene model had the lowest loss of 0.3187. SHAP‑based XAI highlighted DNAJB14 as the most influential gene, and functional validation showed that inhibiting DNAJB14 reverses key malignant traits of HCC cells.
By Ali Bou Nassif, Darko Castven, Manar Abu Talib, Jibran Sualeh Muhammad, Ahmed Ammar Kubba, Jens Marquardt, Abdalla Sayed Ali
arXiv:2606. 09860v1 Announce Type: cross Abstract: Non-alcoholic fatty liver disease (NAFLD) affects roughly 25% of global adults, posing substantial hepatic and cardiovascular risks.
By Xinze Zhang
arXiv:2607. 00472v1 Announce Type: cross Abstract: Cardiovascular disease is still one of the main causes of death around the world.
By Sagnik Ghosh
arXiv:2609.13192v1 Announce Type: new
Abstract: This study compares traditional machine learning models and Large Language Model (LLM)-generated rule-based systems for heart disease prediction using...
By Feisal Alaswad, Batoul Aljaddouh, Maher Alrahhal, Wafaa Al Nassan, Talal Bonn
The paper introduces an imaging-based method that uses large-scale computer vision models to analyze routine abdominal ultrasound images for predicting cirrhosis decompensation. It extracts predictive features beyond traditional laboratory risk scores, offering a non-invasive, low-cost, and scalable approach for early risk stratification. The framework combines automated ultrasound processing with modern deep learning to identify high-risk patients before clinical deterioration occurs.
By Guangyi Zhang, Peiyun Ni, Eugene Cheah, Rajat Chandra, Peng Guo, Raymond T. Chung, Anthony E. Samir
arXiv:2607. 08299v1 Announce Type: new Abstract: Accurate and timely diagnoses are essential for quality patient care.
By Abu Rafe Md Jamil, Nayan Malakar
arXiv:2606. 16337v1 Announce Type: new Abstract: Predictive modeling for clinical tabular data is central to clinical decision support and therefore requires not only strong predictive performance but also transparent decision logic.
By Wei Xu, Ke Yang, Gang Luo, Keli Zheng, Lingyan Hu, Jing Wang, Kefeng Li
EMFE (Efficient Mathematical Feature Extraction) is a lightweight, explainable machine‑learning framework that classifies single red‑blood‑cell images as parasitized or uninfected using five engineered features: Gray World color normalization, adaptive green‑channel thresholding, morphological spot detection, and classical classifiers. On the NIH LHNCBC malaria dataset (27,558 images from 200 patients), a tuned Random Forest achieved 94.6% pooled out‑of‑fold accuracy, 94.3% on a 40‑patient holdout, and outperformed deep‑learning baselines in an accuracy‑efficiency trade‑off. Ablation studies, synthetic perturbations, and explainability analyses identified spot saturation as the dominant discriminative feature and quantified the framework’s failure modes and patient‑level performance.
By Md Abdullah Al Kafi, Walayat Hussain, Mousumi Karmakar, Sumit Kumar Banshal, Ahmed Al Marouf
The paper presents an intelligent system that predicts stroke risk using eleven clinical features and evaluates seven supervised machine learning algorithms. Ensemble methods—Random Forest, Stacking Classifier, and Bagging Classifier—achieved the highest accuracies, reaching 99.52%, while other models such as KNN, TabNet, and a custom feedforward network also performed well. The study demonstrates that ensemble approaches are particularly effective for stroke classification tasks.
By Md Shahriar Sajid