Segmenting ischemic stroke lesions on T1-weighted (T1w) MRI acquired across different scanners and protocols without intensity standardization is difficult because lesions are subtle and share intensi...
arXiv:2608. 19769v1 Announce Type: cross Abstract: Fast and accurate segmentation of Acute Ischemic Stroke (AIS) lesions is essential for stroke prognosis and treatment planning.
By Maunil Shah, Vaanathi Sundaresan
The paper introduces a synthetic training framework for segmenting long‑tail haemorrhagic lesions such as cerebral microbleeds (CMBs) and cortical superficial siderosis (cSS) without requiring real lesion annotations. By starting from anatomical brain parcellations, the method applies spatial augmentation, voxel resampling, and procedural insertion of lesion labels guided by clinical priors, then synthesises images with randomized intensity, blurring, and Rician noise. Models trained on these synthetic image‑label pairs outperformed classical filter baselines, achieving higher AUPRC and AUROC for both cSS and CMB segmentation.
By Yuan Cao, Sumeet Dash, Antonia Zachariadis, Stefanie Schreiber, Katja Neumann, Jose Bernal
arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.
By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo
The study evaluated a pragmatic deep‑learning approach for segmenting acute ischemic stroke lesions on diffusion‑weighted MRI. Using a self‑configured nnU‑Net trained on 1,744 cases and tested on 436, the baseline model achieved a median Dice similarity coefficient of 0.84, outperforming the DeepISLES ensemble, especially for smaller infarcts. The approach required minimal preprocessing and fast inference, suggesting it could streamline clinical stroke imaging workflows.
By Atle Bj{\o}rnerud, Till Schellhorn, Thor H. Skatt{\o}r, Terje Nome, Jon Andr\'e Ottesen, Anne Hege Aamodt, Bradley J MacIntosh
This study presents a domain-aware deep learning framework based on nnU-Net for segmenting ischemic stroke lesions on non‑contrast CT scans and quantifying net water uptake (NWU). Trained on data from Hamburg and the Acute Ischemic Stroke Dataset, the model was fine‑tuned on small target‑domain subsets from Boston and ISLES, achieving median Dice scores of 0.68 and 0.56 for lesions ≥30 mL, and an NWU mean absolute error of 1.37 percentage points on the Boston cohort. The results demonstrate that target‑domain adaptation can enable accurate NCCT‑only infarct segmentation and low‑error NWU estimation across heterogeneous multicenter datasets.
By Linus Britt, Maximilian Nielsen, Susan Klapproth, Andre Kemmling, Michael H. Lev, Gabriel Broocks, Rene Werner, Thilo Sentker
arXiv:2608. 16377v1 Announce Type: cross Abstract: Instance-level lesion detection has been an increasingly larger focal point in medical image segmentation besides the more standard voxel-level overlap.
By Qinghui Liu, Jon Andr\'e Ottesen, Atle Bj{\o}rnerud, Kyrre Eeg Emblem
arXiv:2601. 20503v2 Announce Type: replace-cross Abstract: White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are key imaging biomarkers of cerebral small vessel disease (SVD) detectable on magnetic resonance imaging (MRI).
By Jesse Phitidis, Alison Q. Smithard, William N. Whiteley, Joanna M. Wardlaw, Miguel O. Bernabeu, Maria Vald\'es Hern\'andez
arXiv:2607. 17782v1 Announce Type: cross Abstract: Foundation models pretrained using self-supervised learning have transformed computer vision by learning transferable representations from large-scale unlabeled data.
By Moona Mazher, Abdul Qayyum, Steven A. Niederer, Daniel C. Alexander
arXiv:2608.28787v1 Announce Type: new
Abstract: Joint-embedding predictive architectures (JEPAs) have primarily been developed for self-supervised representation learning. Denoising JEPA (D-JEPA) rec...
By Meng Zhou, Wenhao You, Yuxing Chen, Yueying Tian
arXiv:2510.14383v4 Announce Type: replace
Abstract: Accurate brain tumor segmentation is significant for clinical diagnosis and treatment but remains challenging due to tumor heterogeneity. Mamba-bas...
By Danish Ali, Ajmal Mian, Naveed Akhtar, Ghulam Mubashar Hassan
arXiv:2608. 06264v1 Announce Type: cross Abstract: The development of deep learning over the past decade has revolutionized medical imaging segmentation, allowing the extraction of precise descriptors from large volumes to characterize pathologies.
By Robin Trombetta, Carole Lartizien