arXiv Machine Learning

OTLesMix: Wasserstein Barycenter and Optimal Transport Map for Synthetic Lesion Generation with Diverse Shapes and Locations

arXiv:2608. 06264v1 Announce Type: cross Abstract: The development of deep learning over the past decade has revolutionized medical imaging segmentation, allowing the extraction of precise descriptors from large volumes to characterize pathologies.

arXiv Machine Learning
Jun 18

Structural MRI Synthesis for Alzheimer's Disease via Conditional Diffusion on Anatomical Masks

arXiv:2606. 18354v1 Announce Type: cross Abstract: Recent advances in generative machine learning models have significantly improved medical imaging, offering promising solutions for data augmentation, privacy preservation, and improved model generalization.

By Muge Zhang, Muhammad Ali Khaliq, Jamal Alsakran, Byeong Kil Lee, Jeeho Ryoo
arXiv Machine Learning
Jun 16

Lesion-DDPM: Lesion-Enhanced 3D Diffusion for MS MRI Synthesis

arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.

By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo
arXiv AI
Sep 3

InstEditSeg: Instruction-Driven Image Editing for Polyp and Skin Lesion Segmentation

InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.

By Ziquan Liu, Zhewei Zhu, Xuyang Shi
arXiv AI
Aug 25

SAS: Segment Anything Small for Ultrasound -- A Non-Generative Data Augmentation Technique for Robust Deep Learning in Ultrasound Imaging

The paper introduces Segment Anything Small (SAS), a data‑augmentation method that improves deep‑learning segmentation of small anatomical structures in ultrasound images. SAS uses two transformations: resizing and embedding organ thumbnails into a black background to vary organ scale, and adding noise to regions of interest to mimic tissue texture variability. Experiments on one internal and five external datasets show Dice score gains up to 0.35, with an average improvement of 0.16, and demonstrate that SAS enhances model robustness and generalizability without adding hallucinations or artifacts.

By Danielle L. Ferreira, Ahana Gangopadhyay, Hsi-Ming Chang, Ravi Soni, Gopal Avinash
arXiv AI
Aug 3

DualDiT: A Conditional Dual-Output Diffusion Transformer for Joint OCT Image and Segmentation Mask Generation

arXiv:2607. 29337v1 Announce Type: cross Abstract: Background and Objective: Generating realistic medical images with anatomically accurate segmentation masks helps address the shortage of annotated data in medical imaging, particularly in optical coherence tomography (OCT) of mouse eyes, where manual retinal layer delineation is labour-intensive due to tiny structures and required expertise, resulting in scarce datasets.

By Fernando Garc\'ia-Torres, Roc\'io del Amor, Sandra Morales, \'Alvaro Barroso, Peter Heiduschka, Bj\"orn Kemper, Valery Naranjo
arXiv AI
Jul 2

Controllable Diffusion-Based Lesion Inpainting for Scalable Histopathology Data Augmentation

arXiv:2601. 08127v2 Announce Type: replace-cross Abstract: Expert-annotated training data remains the critical bottleneck for AI in histopathology, particularly for rare pathologies where even dozens of cases may be unavailable.

By Mohamad Koohi-Moghadam, Mohammad-Ali Nikouei Mahani, Rex K. H. Au-Yeung, Raymond Yu O, Monalyn Marabi, Piyapharom Intarawichian, Fabian Z. X. Lean, Andrew Ferguson, Kyongtae Tyler Bae