arXiv:2608. 12779v1 Announce Type: cross Abstract: Understanding the temporal progression of symptoms in clinical narratives is critical for disease monitoring, safety surveillance, and causality assessment.
By Chengyang He, Tahreem Arif, Marko Zivkovic, Lijing Wang, Yue Ning, Ping Wang
CliniCIRCA is a modular large‑language‑model framework that reconstructs longitudinal mental‑health patient journeys from raw electronic health record narratives. It temporally classifies clinical events in unstructured discharge summaries without explicit timestamps, producing 15,891 tagged events from 52 summaries and correcting 629 errors to create verified gold‑standard timelines. The framework then generates temporally grounded summaries, compressing each source by 1.52×, and scales to produce 1,000 silver‑standard timelines for training, showing that instruction tuning improves event extraction, temporal tagging, and summarization across models.
By Aiwei Ivy Zhang, Nimra Ishfaq, Mohit Chandra, Santiago Alvarez Lesmes, Adam Coscia, Khatiya Chelidze Moon, Xiaohan Ding, Munmun De Choudhury
The paper introduces a paired benchmark to detect hindsight bias in clinical language models by comparing model responses to questions posed at a clinically relevant cutoff versus the full timeline. It uses 171 case reports (40 sepsis, 131 GLP‑1/diabetes) with both human‑annotated and LLM‑generated time‑series data, evaluating accuracy, hindsight trap rate, answer instability rate, and hindsight bias rate. Results show that exposing models to the full timeline consistently increases hindsight bias, while truncating the timeline mitigates bias without sacrificing accuracy.
By Misaki Matsuura, Sayantan Kumar, Ojas Kadam, Jeremy C. Weiss
arXiv:2610.01938v1 Announce Type: cross
Abstract: Exam-style accuracy does not establish whether large language models (LLMs) reason well over clinical records. We define clinical reasoning as integr...
By Zhangshu Joshua Jiang, Zina Ibrahim, James T. Teo
arXiv:2607. 21307v1 Announce Type: cross Abstract: The reliance on unstructured free text for documenting clinical trial protocols creates a significant barrier to automated reasoning, cohort discovery, and trial simulation.
By Yan Huang, Xubing Hao, Xiaojin Li, Rashmie Abeysinghe, Xiaoqian Jiang, Licong Cui, Guo-Qiang Zhang
arXiv:2605. 01134v3 Announce Type: replace Abstract: The dominant noun-based modeling paradigm has fundamentally constrained AI development, precluding any adequate representation of the future as an open temporal dimension.
By Jia Li, Vipin Kumar, Rui Zhang