arXiv:2606. 18154v1 Announce Type: new Abstract: Building personalized cardiac electrophysiology (EP) digital twins requires identifying the appropriate model structure for each patient, not merely fitting parameters.
By Ziqi Zhou, Yubo Ye, Sumeet Atul Vadhavka, Linwei Wang, Zhiqiang Tao
arXiv:2607. 00431v1 Announce Type: new Abstract: Forecasting models for health-signal digital twins must preserve the oscillatory, frequency, phase, and state-transition dynamics of physiological signals, yet the pointwise metrics used to benchmark them cannot detect when these fundamental properties are lost.
By Md Rakibul Haque, Shireen Elhabian, Warren Woodrich Pettine
arXiv:2606. 06094v1 Announce Type: cross Abstract: Advances in computational modeling, neuroimaging, and artificial intelligence are revolutionizing the modeling of neurological disorders for improved diagnostics, prognosis, and treatment planning.
By Shah Pallav Dhanendrakumar, Saikat Pal, Sitikantha Roy
arXiv:2608. 09460v1 Announce Type: new Abstract: Cardiac digital twin research is moving from subject-specific anatomical replicas toward virtual cohorts that represent clinically relevant population subgroups.
By Konstantinos Kevopoulos, Beatrice Moscoloni, Benjamin Alheit, Cameron Beeche, Julio A. Chirinos, Alexander Heinlein, Mathias Peirlinck
arXiv:2606. 07488v1 Announce Type: new Abstract: Personalized virtual heart simulations face challenges in model personalization and computational cost.
By Ryan Missel, Xiajun Jiang, Linwei Wang
arXiv:2606. 16219v1 Announce Type: cross Abstract: Digital twin modeling, including control and data assimilation under model uncertainty, often faces an open-ended fidelity problem: adding variables, data streams, and time scales can indefinitely increase model complexity, ultimately producing systems that are difficult to maintain, validate, interpret, and use for stress or safety testing.
By Zongren Zou, Th\'eo Bourdais, Ricardo Baptista, Houman Owhadi
arXiv:2608. 02135v1 Announce Type: cross Abstract: Cardiovascular digital twins aim to create patient-specific computational models that evolve with clinical data to support diagnosis, prognosis, and therapy optimisation.
By Emmanuel Lwele, Francis Chikweto
arXiv:2607. 03585v1 Announce Type: new Abstract: Engineering Digital Twins and Prognostics and Health Management (PHM) systems rely on robust perception modules to extract actionable information from heterogeneous and non-stationary time-series data.
By Quang Hung Pham, Ryad Zemouri, Martin Gagnon, Luc Vouligny
arXiv:2608. 03927v1 Announce Type: new Abstract: Engineered Skeletal Muscle Tissues (ESMs) have become a key structure for biomedical disease modeling and pharmacological screening, yet their functional characterization often relies on simplistic metrics like peak force, discarding critical kinetic information.
By Mattias Luber, Timo Betz
arXiv:2607. 00926v1 Announce Type: cross Abstract: Generalizing machine learning models to environments that differ from their training distribution remains a critical hurdle, particularly when data from the target domain is entirely or partially unavailable.
By Midhun Parakkal Unni, Samuel Kaski
arXiv:2607. 13877v1 Announce Type: new Abstract: Brain tumor progression exhibits spatially heterogeneous growth, patient-specific treatment response, and complex interactions with surrounding anatomy, making accurate long-term prediction challenging.
By Wenxi Liu, Michael Trimboli, Xianqi Li
arXiv:2608. 12805v1 Announce Type: new Abstract: Access to clinical data is essential for developing reliable healthcare machine learning systems, but direct use of electronic health records is constrained by privacy regulation, institutional review, data-use agreements, and the risk of re-identification.
By Akanta Das, Al Amin Farhad, Mrinmoy Sarkar Anto, David Rehkopf, Ayin Vala, Tanmoy Sarkar Pias