arXiv:2606. 20164v1 Announce Type: cross Abstract: Real-world clinical decision support requires reasoning over heterogeneous and longitudinal patient information rather than answering isolated medical questions.
By Aueaphum Aueawatthanaphisut
arXiv:2607. 04907v1 Announce Type: new Abstract: Deploying Large Language Models (LLMs) in high-stakes clinical settings remains limited by structural hallucinations, weak deterministic reasoning over tabular patient data, and omissions in vector retrieval.
By Mohammed Saim Ahmed Quadri, Yunzhe Xue, Justin W. Ady, Usman Roshan
arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).
By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar
arXiv:2605. 30295v2 Announce Type: replace-cross Abstract: Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited.
By Valentina Bui Muti, Eug\'enie Dulout, Ziquan Fu
arXiv:2608. 07796v1 Announce Type: new Abstract: Large language models perform strongly on medical knowledge benchmarks, but reliable clinical deployment requires agents to conduct defensible investigations over heterogeneous, longitudinal records: determining what evidence is needed, retrieving and reconciling structured and free-text data, grounding conclusions in verifiable evidence, and deferring cases that cannot be resolved reliably.
By Veronica Chatrath, Bryan Zhu, George Pu, Jingxuan Fan, Apaar Shanker, Varun Ursekar, Anahita Sharma, Jason Qin, Keqi Han, Soham Dinesh Tiwari, Soham Dan, Vijay Kalmath, Yuan Li, Daniel Yue Zhang, Chenguang Wang, Zainab Doctor, Zhijun Yin, Nigam H. Shah, Yuan Xue
arXiv:2605. 07022v3 Announce Type: replace Abstract: Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature, and discard experimental context, obscuring nuances needed to assess data correctness and coverage.
By Haydn Jones, Yimeng Zeng, Alden Rose, Li S. Yifei, Yining Huang, Kaiwen Wu, Jiaming Liang, Maggie Ziyu Huan, Yoseph Barash, Cesar de la Fuente-Nunez, Osbert Bastani, Zachary Ives, Mark Yatskar, Jacob R. Gardner
arXiv:2508. 16674v2 Announce Type: replace-cross Abstract: Medical report understanding from real-world document images is essential for generating patient-facing explanations and enabling structured information exchange in clinical systems.
By Fangxin Shang, Yuan Xia, Dalu Yang, Yahui Wang, Binglin Yang
arXiv:2603. 01131v3 Announce Type: replace-cross Abstract: Clinical diagnosis is a gradual process of evidence integration, in which physicians move from symptoms and medical history to examinations, competing hypotheses, disease relations, and treatment decisions.
By Yuqi Zhan, Xinyue Wu, Tianyu Lin, Yutong Bao, Xiaoyu Wang, Weihao Cheng, Huangwei Chen, Feiwei Qin, Zhu Zhu
arXiv:2608. 08056v1 Announce Type: new Abstract: Medical data, by its nature, exhibit a high degree of heterogeneity on multiple levels ranging from (a) different modalities like images, text and time series, (b) diverse tabular schemata introduced by institutions and (c) completely unstructured textual information data provided by healthcare professionals.
By Ioannis N. Tzortzis, Georgia Kapetadimitri, Agapi Davradou, Nefeli Kousta, Nikolaos Bakalos, Ioannis Rallis, Dimitrios Kalogeras, Nikolaos Doulamis, Anastasios Doulamis
arXiv:2607. 26155v1 Announce Type: new Abstract: Clinical data-science agents must transform heterogeneous longitudinal records into auditable analyses, yet existing benchmarks largely isolate medical question answering, structured-table reasoning, or generic scientific repositories.
By Yuan Zhu, Ethan B. Liu, Frank Nie, Jindong Han
arXiv:2606. 11675v1 Announce Type: new Abstract: Diagnosing pulmonary diseases requires integrating heterogeneous evidence amid phenotypic variability and cross-disease overlap.
By Haoyang Zeng, Yuanxi Fu, Rongzhen Li, Yuming Yang, Xiao Sun, Jingwang Huang, Gujie Shao, Guohui Xiang, Quan Lu, Dongfan Ye, Xuetao Chen, Jiang Zhong, Kaiwen Wei, Zhi Xu
arXiv:2606. 29876v1 Announce Type: cross Abstract: Modern large language models (LLMs) reach 60-70% diagnostic accuracy on complex clinical case benchmarks, but accuracy alone cannot distinguish stable clinically-grounded reasoning from pattern matching.
By Nisarg A. Patel (University of California, San Francisco)