arXiv Machine Learning

Estimating Individualized Treatment Effects in Acute Ischemic Stroke with Causal Transformation Models (TRAM-DAG): A Multi-Centre Observational Study with External RCT Validation

arXiv:2606. 12623v2 Announce Type: replace-cross Abstract: Personalized medicine in acute ischemic stroke requires moving beyond average treatment effects (ATE) to individualized treatment effect (ITE) estimates to support treatment decisions.

arXiv AI
Aug 12

Expert-Guided g-computation with Large Language Models for Estimating Causal Effects on Timings: Applications to Hospital Quality Improvement

arXiv:2608. 10339v1 Announce Type: cross Abstract: Hospital quality improvement (QI) programs routinely face multiple candidate interventions to optimize hospital flow, but existing methods struggle to estimate and rank the causal effects of such interventions.

By Patrick Vossler, Jialin Ouyang, F. Richard Guo, Anran Huang, Ali Shojaie, Lucas Zier, Fan Xia, Jean Feng
arXiv AI
Aug 7

From Continuous Predictors to Clinical Thresholds: Early Evidence on Performance Trade-offs of Guideline-Based Categorisation for Ischaemic Stroke Outcome Prediction

arXiv:2608. 05203v1 Announce Type: new Abstract: Machine learning models achieve strong predictive accuracy for 90-day outcome prediction in acute ischaemic stroke, yet clinical adoption is limited by the misalignment of model explanations with clinicians' reasoning.

By Esra Zihni, Katryna Cisek, Hamzah Ziadeh, Hendrik Knoche, Robert Mikulik, John D. Kelleher
arXiv AI
Sep 1

Federated Learning for MRI-based BrainAGE: a multicenter study on post-stroke functional outcome prediction

arXiv:2506.15626v3 Announce Type: replace-cross Abstract: $\textbf{Objective:}$ Brain-predicted age difference (BrainAGE) is a neuroimaging biomarker reflecting brain health. However, training robust...

By Vincent Roca, Marc Tommasi, Paul Andrey, Aur\'elien Bellet, Markus D. Schirmer, Hilde Henon, Laurent Puy, Julien Ramon, Gr\'egory Kuchcinski, Martin Bretzner, Renaud Lopes
arXiv Machine Learning
Sep 14

In-Hospital Stroke Risk-State Classification from PPG-Derived Hemodynamic Features

The study develops a 1‑D ResNet classifier that uses a fixed 17‑channel hemodynamic representation derived from photoplethysmography (PPG) to predict in‑hospital stroke risk states up to six hours before clinical recognition. Using data from MIMIC‑III and MC‑MED, the model achieved F1‑scores ranging from 0.7956 to 0.9888 across 4‑, 5‑, and 6‑hour horizons, outperforming four non‑waveform clinical and structured‑EHR comparators in all cohort‑horizon settings. Retrospective analysis showed that the PPG model’s false‑positive rates on high‑risk non‑stroke controls could be reduced through persistence aggregation, though the study does not establish a calibrated bedside alarm or a clinically validated prediction lead time.

By Jiaming Liu, Cheng Ding, Jian Wu, Hongxia Xu, Daoqiang Zhang
arXiv AI
Jun 15

Can LLMs Accurately Score Medical Diagnoses and Clinical Reasoning?

arXiv:2604. 14892v3 Announce Type: replace-cross Abstract: Evaluating medical AI systems using expert clinician panels is costly and slow, motivating the use of large language models (LLMs) as alternative adjudicators.

By Amy Rouillard, Sitwala Mundia, Linda Camara, Ziyaad Dangor, Michael Cameron Gramanie, Ismail Kalla, Shabir A. Madhi, Kajal Morar, Marlvin T. Ncube, Haroon Saloojee, Bruce A. Bassett