arXiv AI

Latent Decision Flow Rewards for Clinical Guideline Reasoning

The paper introduces GUIDER, a method that jointly trains a decision flow controller and a reasoning policy to improve clinical guideline reasoning. GUIDER generates multiple plausible decision flows from guideline supervision, computes process rewards across these flows, and gates them on answer correctness to address both path–answer gaps and path multiplicity. Experiments on MedGUIDE and out‑of‑domain benchmarks show that GUIDER outperforms existing reinforcement learning baselines, achieving higher weighted accuracy and guideline adherence.

arXiv AI
Oct 15

Reinforcement Learning In Partially Verifiable Environments for Colon Cancer Treatment Planning

arXiv:2610.17426v1 Announce Type: cross Abstract: Clinical decision-making is a sequential process of information collection, clinical inference, and forecasting under partial observability, often wi...

By Li-Ching Chen, Andr\'es Franco Valiente, Yuta Ishiyama, Zachary R. Chalmers, William Chen, Kelsey Natsuhara, Taema Brinjikji, Madhumita Sushil, Travis Zack, Julian C. Hong
arXiv AI
Jun 30

An AI agent for treatment reasoning over a biomedical tool universe

arXiv:2606. 28692v1 Announce Type: new Abstract: Treatment reasoning underpins every therapeutic decision, integrating disease context, comorbidities, medications, contraindications, and evolving biomedical knowledge to select an appropriate therapy.

By Shanghua Gao, Ayush Noori, Richard Zhu, Curtis Ginder, Zhenglun Kong, Xiaorui Su, Justin Kauffman, Benjamin S. Glicksberg, Joshua Lampert, Ankit Sakhuja, Ashwin Sawant, ATHENA-R1 Evaluation Consortium, David A. Clifton, Noa Dagan, Ran Balicer, Marinka Zitnik
arXiv AI
6d ago

Aligning Medical Vision Language Models at the Capability Boundary with Entropy Adaptive Rubric Grounding

The paper introduces MedCBR, a two‑stage alignment framework for medical vision‑language models that improves diagnostic reasoning at the capability boundary. First, it uses Difficulty Weighted Boundary Preference Optimization (DBPO) to focus learning on counterfactual boundary cases, and second, it applies Entropy Gated Grounded Policy Optimization (EGPO) to reward anatomical grounding and reasoning fidelity while mitigating rubric noise. Experiments on six medical benchmarks demonstrate consistent accuracy gains, especially on challenging differential diagnosis tasks, with the combined stages delivering super‑additive improvements.

By Hongyu Bai, Jiaqi Zeng, Chunzheng Zhu
arXiv AI
Aug 10

ResidencyRL: Reinforcement Learning in Simulated Clinical Environments

arXiv:2608. 07418v1 Announce Type: new Abstract: In medical education, physicians convert academic knowledge into clinical expertise through residency: years of training across thousands of encounters, with diverse sources of feedback and progressively greater autonomy.

By Valentin Li\'{e}vin, Samuel Schmidgall, Tim Strother, Alex Bijamov, Akshay Goel, Anil Palepu, Chunjong Park, Vahid Balazadeh, Min Woo Sun, Marius Guerard, Justin Chen, Dave Steiner, Vikram Dhillon, Ibrahim Azar, Akhil Mehta, Nicholas Spetsieris, Shilpan Shah, Maen Abdelrahim, Amit Dahiya, Yun Liu, Katherine Chou, Yossi Matias, Avinatan Hassidim, Dale R. Webster, Quoc V. Le, Raia Hadsell, Joelle Barral, Carey Radebaugh, Aleksandra Faust, Shekoofeh Azizi, Mike Schaekermann, Po-Hsuan Cameron Chen, Tao Tu, David Racz, Lin Yang
Hugging Face Trending Papers
Sep 28

RGDT-Bench: Benchmarking LLM Reasoning for Rule-Governed Decisions and Their Justifications

RGDT-Bench is a new benchmark that evaluates large language models on Rule‑Governed Decision Tasks, where models must apply external rules to facts, justify decisions, and provide checkable justifications. The benchmark offers 202.1K condition‑level supervision slots across four task tracks and eight task‑probe combinations, and it labels warrant completeness through label‑blind extraction and deterministic checks. Evaluation shows that among correct responses, 40.2% of warrants are incomplete, and existing evaluators struggle to detect this, prompting the authors to train a reward model that improves AUROC to 69.24% and outperforms outcome‑supervised baselines.

arXiv Machine Learning
Jun 2

OncoReason: Structuring Clinical Reasoning in LLMs for Robust and Interpretable Survival Prediction

arXiv:2510. 17532v2 Announce Type: replace-cross Abstract: Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data.

By Raghu Vamshi Hemadri, Geetha Krishna Guruju, Kristi Topollai, Anna Ewa Choromanska