Medical foundation models learn latent representations of clinically meaningful phenotypes, yet their ability to support controllable image generation remains largely unexplored. We evaluate four retinal foundation models within the representation tokenizer framework and examine whether demographic and clinical information encoded in latent representations from foundation models is preserved during synthetic image generation.
arXiv:2603. 18846v3 Announce Type: replace-cross Abstract: Foundation models are used to extract transferable representations from large amounts of unlabeled data, typically via self-supervised learning (SSL).
arXiv:2608. 09752v1 Announce Type: cross Abstract: Retinal fundus images frequently exhibit multiple co-occurring pathologies, yet standard deep learning classifiers apply static, identical computation to every image regardless of the underlying disease distribution.
arXiv:2609.24691v1 Announce Type: new Abstract: Latent diffusion models now dominate medical image generation, and every such pipeline rests on a \emph{tokenizer} that compresses images into the late...
arXiv:2608.24723v1 Announce Type: new Abstract: Retinal fundus photography is widely used for screening and monitoring ocular diseases, but many modern classification pipelines rely on deep latent re...
arXiv:2609.39635v1 Announce Type: new Abstract: Given a target dataset, such as faces with eyeglasses, and a background dataset, such as faces without, contrastive analysis separates \textit{salient}...
The paper explores contrastive self‑supervised learning (SSL) for retinal fundus image classification, comparing SimSiam and SimCLR under limited data and computational resources. It investigates how retinal‑specific augmentation strategies and training parameters affect representation quality, evaluated through linear probing and fine‑tuning on multi‑disease classification and diabetic retinopathy grading tasks. The results demonstrate that tailored augmentations enable lightweight SSL models to learn transferable representations, reducing reliance on large annotated datasets while achieving competitive performance.
Retinal fundus photography is widely used for screening and monitoring ocular diseases, but many modern classification pipelines rely on deep latent representations and provide limited interpretabilit...
arXiv:2609.12834v1 Announce Type: new Abstract: Modelling how a disease progresses over time requires longitudinal imaging cohorts, which are scarce and small, whereas cross-sectional data -- one ima...
The paper presents a method for generating cardiac magnetic resonance (CMR) images conditioned on patient metadata using a pretrained latent diffusion model. By encoding structured clinical data and slice position as textual prompts and applying Metadata‑Free Classifier‑Free Guidance, Contrastive Batching, and Inverse‑Frequency Sampling, the authors improve the fidelity of synthetic images, achieving a 57% reduction in Fréchet Inception Distance compared to a baseline without these strategies. Evaluation on 59,058 UK Biobank CMR scans shows better distributional realism and subgroup alignment, though disease‑specific conditioning remains challenging.
MedDiME is a latent-space, classifier‑guided diffusion framework designed for medical counterfactual image generation. It introduces a gradient‑driven adaptive masking mechanism that works directly in latent space, enabling spatially precise edits while avoiding the high computational and memory costs of pixel‑space methods. Experiments show MedDiME can produce high‑quality counterfactuals up to 40× faster and using 13× less GPU memory than previous diffusion baselines.
arXiv:2607. 29337v1 Announce Type: cross Abstract: Background and Objective: Generating realistic medical images with anatomically accurate segmentation masks helps address the shortage of annotated data in medical imaging, particularly in optical coherence tomography (OCT) of mouse eyes, where manual retinal layer delineation is labour-intensive due to tiny structures and required expertise, resulting in scarce datasets.
arXiv:2610.00414v1 Announce Type: new Abstract: Foundation models pretrained on large-scale datasets demonstrate strong transferability to medical imaging tasks. However, understanding how their late...