arXiv Machine Learning

Adaptive Routing for Efficient Diffusion Transformer-Based PNI Prediction

arXiv:2607. 11533v1 Announce Type: cross Abstract: Perineural invasion (PNI) is a critical prognostic factor in cholangiocarcinoma.

arXiv AI
Jul 14

LoSA-Net: A Localized and Scale-Adaptive Network for Boundary-Sensitive Prediction of Perineural Invasion in 3D MRI

arXiv:2607. 10992v1 Announce Type: cross Abstract: Perineural invasion (PNI) is a clinically relevant indicator of tumor aggressiveness and can influence surgical decision-making, motivating interest in reliable preoperative assessment.

By Youngung Han, Hyunsu Go, Kyeonghun Kim, Induk Um, Junga Kim, Jaewon Jung, Woo Kyoung Jeong, Won Jae Lee, Pa Hong, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim
arXiv Computer Vision
Sep 11

SCINTILLA-SNN: A Spiking Multi-Scale Selective Aggregation Network for Perineural Invasion Prediction

SCINTILLA‑SNN is a 3D spiking neural network designed to predict perineural invasion (PNI) in cholangiocarcinoma (CCA) from MRI scans. It uses a four‑stage hierarchical backbone and a Multi‑Scale Spike Aggregation module to focus on sparse, localized PNI cues while reducing computational load. In a 10‑year retrospective study of 182 patients, the model achieved an AUROC of 0.748 and cut inference energy by over 23× compared to dense MAC‑only approaches.

By Youngung Han, Yului Jeong, Kyeonghun Kim, Dohyun Kweon, Suah Park, Hyunsu Go, Sungha Park, Anna Jung, Jinyong Jun, Yunho Choe, Yunjin Seo, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim
Hugging Face Trending Papers
Sep 10

Order-Aware 2.5D Multiple Instance Learning for Preoperative MRI-Based Perineural Invasion Risk Assessment in Intrahepatic Cholangiocarcinoma

The paper introduces Order-Aware Slab Multiple Instance Learning (OAS‑MIL) for predicting perineural invasion (PNI) in intrahepatic cholangiocarcinoma using preoperative T2‑weighted MRI. It treats each tumor‑centered MRI crop as an ordered sequence of overlapping 2.5D slabs, extracting slab‑level features with a shared encoder and aggregating them through both permutation‑invariant set‑attention and bidirectional sequence‑attention branches. In five‑fold patient‑level cross‑validation, OAS‑MIL achieved a mean AUROC of 0.770, outperforming volumetric and MIL baselines, indicating that axial order provides a useful inductive bias for weakly supervised PNI prediction.

arXiv Computer Vision
Sep 11

Order-Aware 2.5D Multiple Instance Learning for Preoperative MRI-Based Perineural Invasion Risk Assessment in Intrahepatic Cholangiocarcinoma

The paper introduces Order‑Aware Slab Multiple Instance Learning (OAS‑MIL), a weakly supervised method that predicts perineural invasion (PNI) risk in intrahepatic cholangiocarcinoma using preoperative T2‑weighted MRI. Tumor‑centered MRI crops are split into ordered 2.5D slabs, and a shared encoder extracts features that are aggregated through both permutation‑invariant set‑attention and bidirectional sequence‑attention branches. In five‑fold patient‑level cross‑validation, OAS‑MIL achieved a mean AUROC of 0.770, outperforming volumetric and other MIL baselines, indicating that preserving axial order improves non‑invasive PNI prediction.

By Hyunsu Go, Youngung Han, Kyeonghun Kim, Jinyong Jun, Junbeom Lee, Dohyun Kweon, Yului Jeong, Suah Park, Sungha Park, Anna Jung, Woo Kyoung Jeong, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim
arXiv AI
Sep 16

MUMINS: Metadata-conditioned Uncertainty-aware Medical Image Next-state Synthesis

arXiv:2609.17169v1 Announce Type: cross Abstract: Forecasting anatomical changes such as tumor growth and neurodegeneration is a challenging generative vision task. Morphological evolution is subtle...

By Anna Oliveras, Roger Mar\'i, Rafael Redondo, Oriol Guardi\`a, Cynthia Ifeyinwa Ugwu, Ana Tost, Bhalaji Nagarajan, Carolina Migliorelli, Vicent Ribas, Petia Radeva
arXiv Machine Learning
Jul 15

SpikeDS: Dual Sparsity Spikformer for Perineural Invasion Prediction in 3D MRI

arXiv:2607. 11986v1 Announce Type: cross Abstract: Perineural invasion (PNI) is associated with poor prognosis in cholangiocarcinoma (CCA).

By Induk Um, Youngung Han, Kyeonghun Kim, Yului Jeong, Jina Jeong, Hyunsu Go, Dohyun Kweon, Sungha Park, Junga Kim, Anna Jung, Suah Park, Hyuk-Jae Lee, Pa Hong, Woo Kyoung Jeong, Won Jae Lee, Ken Ying-Kai Liao, Nam-Joon Kim
arXiv AI
Sep 10

Diffusion Model in Latent Space for Medical Image Segmentation Task

The paper introduces MedSegLatDiff, a diffusion-based framework that combines a variational autoencoder (VAE) with a latent diffusion model for medical image segmentation. By compressing images into a low-dimensional latent space, the method reduces noise and speeds up training, while a weighted cross‑entropy loss preserves tiny structures such as small nodules. Evaluated on ISIC‑2018, CVC‑Clinic, and LIDC‑IDRI datasets, MedSegLatDiff achieves state‑of‑the‑art Dice and IoU scores, generates diverse segmentation hypotheses, and produces confidence maps that enhance interpretability and reliability for clinical deployment.

By Ngoc Huynh Trinh, Hai Toan Nguyen, Son Ba Luong, Quoc Long Tran
arXiv Machine Learning
1d ago

A foundation for systematic analysis of transformers and RNNs for tractography

The paper presents a systematic comparison of recurrent neural networks and Transformer models for iterative diffusion MRI tractography, focusing on training strategies, input representations, and hyperparameter tuning. It introduces a generation‑validation phase that provides streamline‑level supervision, enabling the models to achieve the best performance reported on the ISMRM2015 challenge dataset. The study also evaluates the effects of missing bundles, noisy training data, and invalid fibers, and demonstrates applicability to in‑vivo data from the Tractoinferno database.

By Emmanuelle Renauld, Philippe Poulin, Hugo Larochelle, Antoine Th\'eberge, Maxime Descoteaux