arXiv:2607. 10992v1 Announce Type: cross Abstract: Perineural invasion (PNI) is a clinically relevant indicator of tumor aggressiveness and can influence surgical decision-making, motivating interest in reliable preoperative assessment.
By Youngung Han, Hyunsu Go, Kyeonghun Kim, Induk Um, Junga Kim, Jaewon Jung, Woo Kyoung Jeong, Won Jae Lee, Pa Hong, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim
arXiv:2607. 11986v1 Announce Type: cross Abstract: Perineural invasion (PNI) is associated with poor prognosis in cholangiocarcinoma (CCA).
By Induk Um, Youngung Han, Kyeonghun Kim, Yului Jeong, Jina Jeong, Hyunsu Go, Dohyun Kweon, Sungha Park, Junga Kim, Anna Jung, Suah Park, Hyuk-Jae Lee, Pa Hong, Woo Kyoung Jeong, Won Jae Lee, Ken Ying-Kai Liao, Nam-Joon Kim
arXiv:2605.05522v3 Announce Type: replace-cross
Abstract: Although self-supervised pretraining is expected to learn broadly transferable representations, its effectiveness across imaging modalities s...
By Aneesh Rangnekar, Joao Miranda, Natally Horvat, Stephanie Chahwan, Samir Alrayess, Aditya Apte, Aditi Iyer, Eve LoCastro, Revathi Ravella, Marc J Gollub, Iva Petkovska, Jesse Joshua Smith, Paul Romesser, Julio Garcia-Aguilar, Harini Veeraraghavan, Joseph O Deasy
arXiv:2607. 11533v1 Announce Type: cross Abstract: Perineural invasion (PNI) is a critical prognostic factor in cholangiocarcinoma.
By Youngung Han, Dohyun Kweon, Kyeonghun Kim, Hyunsu Go, Jina Jeong, Suah Park, Induk Um, Junga Kim, Anna Jung, Yului Jeong, Sungha Park, Jinyong Jun, Pa Hong, Woo Kyoung Jeong, Won Jae Lee, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim
arXiv:2602. 05387v2 Announce Type: replace-cross Abstract: MRI provides superior soft tissue contrast without ionizing radiation; however, the absence of electron density information limits its direct use for dose calculation.
By Zolnamar Dorjsembe, Hung-Yi Chen, Furen Xiao, Hsing-Kuo Pao
The paper introduces MSM‑Seg, a dual‑memory segmentation framework for 3D multi‑modal brain tumor segmentation. It combines a modality‑and‑slice memory attention module to capture cross‑modal and spatial‑slice dependencies, a multi‑scale category‑agnostic prompt encoder for whole‑tumor guidance, and a modality‑adaptive fusion decoder to integrate complementary decoding information. Experiments on various MRI datasets show that MSM‑Seg surpasses state‑of‑the‑art methods for metastases and glioma tumor segmentation.
By Yuxiang Luo, Qing Xu, Hai Huang, Yuqi Ouyang, Xiangjian He, Zhen Chen, Wenting Duan, Jiebo Luo
The paper introduces Order-Aware Slab Multiple Instance Learning (OAS‑MIL) for predicting perineural invasion (PNI) in intrahepatic cholangiocarcinoma using preoperative T2‑weighted MRI. It treats each tumor‑centered MRI crop as an ordered sequence of overlapping 2.5D slabs, extracting slab‑level features with a shared encoder and aggregating them through both permutation‑invariant set‑attention and bidirectional sequence‑attention branches. In five‑fold patient‑level cross‑validation, OAS‑MIL achieved a mean AUROC of 0.770, outperforming volumetric and MIL baselines, indicating that axial order provides a useful inductive bias for weakly supervised PNI prediction.
SCINTILLA‑SNN is a 3D spiking neural network designed to predict perineural invasion (PNI) in cholangiocarcinoma (CCA) from MRI scans. It uses a four‑stage hierarchical backbone and a Multi‑Scale Spike Aggregation module to focus on sparse, localized PNI cues while reducing computational load. In a 10‑year retrospective study of 182 patients, the model achieved an AUROC of 0.748 and cut inference energy by over 23× compared to dense MAC‑only approaches.
By Youngung Han, Yului Jeong, Kyeonghun Kim, Dohyun Kweon, Suah Park, Hyunsu Go, Sungha Park, Anna Jung, Jinyong Jun, Yunho Choe, Yunjin Seo, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim
arXiv:2606. 11107v1 Announce Type: cross Abstract: Clinicians diagnose brain tumors by synthesizing patient symptoms, medical history, and quantitative imaging data from modalities such as MRI and CT scans into a unified clinical judgement.
By Wajih ul Islam, Muhammad Yaqoob, Javed Ali Khan, Volker Steuber
arXiv:2510.14383v4 Announce Type: replace
Abstract: Accurate brain tumor segmentation is significant for clinical diagnosis and treatment but remains challenging due to tumor heterogeneity. Mamba-bas...
By Danish Ali, Ajmal Mian, Naveed Akhtar, Ghulam Mubashar Hassan
MTMed3D is a multi-task Transformer-based model that jointly performs 3D detection, segmentation, and classification in medical imaging. It uses a shared Transformer encoder to produce multi-scale features, with separate CNN decoders for each task. Evaluated on BraTS 2018 and 2019, it achieves strong results, especially in detection, while reducing computational cost and inference time compared to single-task models.
By Fan Li, Arun Iyengar, Lanyu Xu
The paper introduces Order‑Aware Slab Multiple Instance Learning (OAS‑MIL), a weakly supervised method that predicts perineural invasion (PNI) risk in intrahepatic cholangiocarcinoma using preoperative T2‑weighted MRI. Tumor‑centered MRI crops are split into ordered 2.5D slabs, and a shared encoder extracts features that are aggregated through both permutation‑invariant set‑attention and bidirectional sequence‑attention branches. In five‑fold patient‑level cross‑validation, OAS‑MIL achieved a mean AUROC of 0.770, outperforming volumetric and other MIL baselines, indicating that preserving axial order improves non‑invasive PNI prediction.
By Hyunsu Go, Youngung Han, Kyeonghun Kim, Jinyong Jun, Junbeom Lee, Dohyun Kweon, Yului Jeong, Suah Park, Sungha Park, Anna Jung, Woo Kyoung Jeong, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim