arXiv Machine Learning

Auditable Context-Aware HFMD Forecasting with Structured LLM Agents

arXiv:2511. 23276v2 Announce Type: replace Abstract: Effective HFMD surveillance requires forecasts capturing both time-series patterns and contextual drivers such as school calendars, weather, and policy or surveillance reports.

arXiv AI
Aug 25

LLM-based Agents for Forecasting and Prediction: Methods, Training, Evaluation, and Applications

arXiv:2608.23058v1 Announce Type: new Abstract: Large language models (LLMs) now support forecasting systems that combine language-based reasoning with temporal data, evidence retrieval, external too...

By Xiaogang Xu, Jiaqi Tang, Jianmin Chen, Yingying Yan, Zhenchao Tang, Xiangxin Zhou, Xiaobin Hu, Wei Wei, Jinfeng Wu, Qifeng Chen, Lu Zhou, Jiafei Wu, Zhe Liu, Jianwei Yin, Weimin Zheng
arXiv Machine Learning
Sep 22

A Patient World Model for Early Forecasting of Digital Health Campaign Outcomes: Capabilities and Limits

The paper introduces a compact patient world model that forecasts digital health campaign outcomes by maintaining a latent state per patient and learning exposure‑conditioned dynamics. Evaluated on a large US campaign dataset, the model predicts new‑to‑brand prescription volume with low relative error (2.9% at week‑4 cutoff) compared to much higher errors from baseline classifiers. The study also shows that dense next‑exposure supervision is crucial for accurate forecasts when conversions are rare and highlights limitations in interpreting exposure‑conditioned rollouts causally.

By Yunlong Wang
arXiv AI
Sep 10

PGP-Clinical-TimeKAN: Prior-Guided Joint Probabilistic Forecasting of Clinical Trajectories

PGP-Clinical-TimeKAN is a trajectory-first framework for joint probabilistic forecasting of multivariate physiological data, combining missingness-aware temporal encoders, a soft organ-system prior, patient-specific relations, nonlinear Kolmogorov‑Arnold messages, and a low‑rank multivariate Student‑t head. Evaluated on a MIMIC‑IV cohort of 6,882 patients, it achieves the second‑lowest normalized MAE and the lowest RMSE among 13 models, while providing calibrated probabilistic forecasts with empirical coverage at 50%, 80%, and 95% intervals. Ablation studies show that relational structure is critical for performance, and increasing covariance rank improves likelihood but not point accuracy. whyItMatters":"The model demonstrates that joint trajectory forecasting can yield highly accurate, calibrated predictions of physiological trajectories, offering a potentially inspectable intermediate task for clinical deterioration prediction."

By Weizhi Nie, Rihao Chang, Weijie Wang, Yuting Su
arXiv AI
Sep 1

INTERVenE: Temporal-Abstraction-Interval Based Transformers for Short-Horizon Medical Event Prediction

INTERVenE introduces Transformer models that use a knowledge‑based temporal abstraction (KBTA) token stream of named clinical concepts instead of raw measurements, enabling per‑token attributions to resolve directly to clinical concepts. Two variants are offered: an auto‑regressive decoder that generates future abstraction trajectories with step‑wise risk readouts, and a bidirectional encoder that jointly predicts risk and time‑to‑event in a single pass. On 57,078 MIMIC‑IV admissions, the encoder variant outperforms neural baselines with a support‑weighted AUPRC of 0.672 and AUROC of 0.901, while the decoder provides complementary token‑level risk trajectories.

By Shahar Oded, Yuval Shahar
arXiv AI
Aug 18

Foresight-England: Development of a National-Scale Generative AI Model of Electronic Health Records for Medical Event Prediction across the COVID-19 Pandemic

arXiv:2608. 16273v1 Announce Type: cross Abstract: Foresight-England (Foresight-E) is the first national-scale generative foundation model of electronic health records (EHRs), developed as a research pilot strictly for COVID-19 research.

By Simon Ellershaw, Christopher Tomlinson, Zeljko Kraljevic, Spiros Denaxas, Harry Hemingway, Cathie Sudlow, Angela M. Wood, Anoop D. Shah, Richard Dobson
arXiv AI
Aug 5

CastFSR: A Fast--Slow--Reflect Agentic Reasoning Framework for Context-Aware Time Series Forecasting

arXiv:2608. 03031v1 Announce Type: new Abstract: Time series forecasting is fundamental to decision-making in complex systems, where future dynamics are influenced not only by historical observations but also by evolving contextual features.

By Xiaoyu Tao, Mingyue Cheng, Bokai Pan, Chuang Jiang, Huanjian Zhang, Tian Gao, Yaguo Liu, Qi Liu, Enhong Chen