The paper introduces an end‑to‑end framework for detecting and classifying cells in pathology images by jointly modeling visual features and instance‑level interactions. It employs a dynamic graph construction module that builds cell graphs from learnable queries and an instance‑aware graph network that filters and reorganizes features, integrating appearance and relational evidence. Experiments on multiple staining protocols show the method surpasses existing approaches in both detection and classification accuracy.
By Ruochen Liu, Yalin Zheng, Jingxin Liu, Jianfeng Zhang, Shoujun Huang, Dexing Kong, Haofeng Li, Wei Lou
arXiv:2506. 11152v4 Announce Type: replace-cross Abstract: Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell level.
By Hiren Madhu, Jo\~ao Felipe Rocha, Tinglin Huang, Siddharth Viswanath, Smita Krishnaswamy, Rex Ying
arXiv:2609.25088v1 Announce Type: cross
Abstract: Survival prediction for glioblastoma multiforme (GBM) demands models that are both accurate and interpretable, yet existing approaches treat these ob...
By Mushahid Intesum
arXiv:2606. 29773v1 Announce Type: new Abstract: Graphs are widely used to model relational systems, with applications in domains such as social networks, finance, and biomedicine.
By Haoxin Sun, Yiqing Lin, Yajun Huang, Chenhui Dong, Mingjun Li, Zhongzhi Zhang
arXiv:2607. 16303v1 Announce Type: cross Abstract: Medical Vision-Language Models (Med-VLMs) require reliable reasoning from fine-grained visual evidence, yet existing models can produce plausible clinical answers by relying on language priors or medical templates rather than truly attending to diagnosis-critical regions.
By Yunhang Qian, Jiaquan Yu, Jiawei Liu, Meng Wang, Hongwei Bran Li, Xiaobin Hu
arXiv:2607. 18218v1 Announce Type: cross Abstract: Foundation models have emerged as a driving force in computational pathology, with the potential to transform cancer diagnosis, prognosis, and treatment selection by learning transferable representations from large-scale histopathology data.
By Naoto Usuyama, Jeya Maria Jose Valanarasu, Sicong Yao, Hanwen Xu, Jaspreet Bagga, Guanghui Qin, Robert E. Kramer, Cliff Wong, Soohee Lee, Hao Qiu, Theodore Zhengde Zhao, Racheli Ben Shimol, Angela Crabtree, Kevin Matlock, Eduardo Alejandro Lozano Garcia, Naiteek Sangani, Alberto Santamaria-Pang, Jason Entenmann, Alexandra Q. Bartlett, Bill J. Wright, Bernard A. Fox, Brian Piening, Sheng Zhang, Sheng Wang, Tristan Naumann, Carlo Bifulco, Hoifung Poon
arXiv:2607. 20896v1 Announce Type: new Abstract: Spatial transcriptomics assays remain costly and technically demanding, restricting transcriptome-wide profiling to specialist settings and preventing routine clinical deployment.
By Kritanu Chattopadhyay, Soumya Chatterjee, Ondrej Krejcar, Debotosh Bhattacharjee
The paper introduces a biology-informed heterogeneous graph representation that models retinal vessel segments, intercapillary areas, and the foveal avascular zone to predict diabetic retinopathy stages from OCTA images. This graph-based approach reframes staging as a graph-level classification task solved with a graph neural network, achieving AUC-ROC values up to 84% and outperforming biomarker-based classifiers, CNNs, and vision transformers. The method also provides detailed, interpretable explanations by precisely localizing abnormal vessels and non-perfusion areas.
By Laurin Lux, Alexander H. Berger, Maria Romeo Tricas, Richard Rosen, Alaa E. Fayed, Sobha Sivaprasada, Linus Kreitner, Jonas Weidner, Martin J. Menten, Daniel Rueckert, Johannes C. Paetzold
arXiv:2606. 05756v1 Announce Type: new Abstract: Graph Neural Networks (GNNs) have demonstrated remarkable performance across a range of applications involving graph-structured data, particularly in high-stakes domains.
By Jialiang Yin, Zheng Zhao, Linsey Pang, Bo Dong, Bin Shi, Jiaxing Zhang
The paper introduces ReasonCVS, a structured reasoning framework for assessing the Critical View of Safety in laparoscopic cholecystectomy. It uses a Vision‑Language Model to build an Anatomical Scene Graph Abstraction and a Large Language Model–based Rationale‑Aware Reasoning Agent to verify sub‑criteria, producing a final verdict with traceable clinical rationale. Experiments on the Endoscapes‑CVS201 benchmark show ReasonCVS outperforms existing methods with a 68.1% mAP while offering interpretable, criterion‑level explanations.
By Qing Xu, Yuxiang Luo, Zhen Chen
arXiv:2607. 23794v1 Announce Type: cross Abstract: Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification.
By Chi Phan, Tianyi Zhang, Yufeng Wu, Qiaochu Xue, Jiajie Zhang, Linghan Cai, Zeyu Liu, Sudong Wang, Yueming Jin, Dan Hu
arXiv:2607. 04557v1 Announce Type: cross Abstract: Accurate prediction of patient-specific therapeutic response from pre-treatment transcriptomes is hindered by the scarcity of matched clinical response labels and post-treatment molecular profiles.
By Dongmin Bang, Sugyun An, Inyoung Sung, Ilho Yun, Sun Kim, Sangseon Lee