arXiv Machine Learning

ORION-CMR: On-scanner Reporting with Integrated Foundation Model for End-to-End Cardiac MRI Analysis and Interpretation

ORION‑CMR is a scanner‑native, end‑to‑end foundation model for cardiac MRI that performs sequence classification, ventricular function assessment, LGE detection, disease classification, and generates reports in about 90 seconds. Trained on 12.9 million images, it outperformed supervised baselines and a prior CMR foundation model, achieving state‑of‑the‑art LGE classification and scar segmentation. In a multi‑vendor clinical cohort, it reached an AUC of 0.96 for normal‑vs‑abnormal detection and 0.88 for multiclass disease classification, with generated reports agreeing 81.4% with expert interpretation.

arXiv AI
Jun 2

CardioLens: Revealing the Clinical Reality Gap of MLLMs via Multi-Sequence Cardiac MRI Evaluations

arXiv:2606. 00123v1 Announce Type: cross Abstract: Multimodal Large Language Models (MLLMs) have shown strong performance on public medical benchmarks, yet existing evaluations often remain weak proxies for clinical use, relying on isolated inputs and simplified recognition-style tasks.

By Zixian Su, Hongkai Zhang, Fan Gao, Encheng Su, Taiping Qu, Jingwei Guo, Nan Zhang, Hui Wang, Zhen Zhou, Kairui Bo, Yan Chen, Yue Ren, Shuai Li, Lei Xu, Henggui Zhang
arXiv Computer Vision
Sep 2

CMRVision: A Foundation Model for Cardiac MR Image Analysis

CMRVision is a cardiac magnetic resonance (CMR) foundation model trained with DINOv3-style self‑supervised learning on 36 million multi‑center, multi‑sequence CMR images. It outperforms prior natural‑image, medical‑image, supervised, and CMR baselines on multi‑task segmentation (cine, LGE, mapping) and cine view classification, achieving Dice scores of 0.940–0.967 for LV and 0.855–0.905 for myocardium, and a zero‑shot Dice of 0.692 on unseen LGE long‑axis views. The model demonstrates robust cross‑view generalization and highest average accuracy (0.906) for cine view classification.

By Athira J. Jacob, Puneet Sharma, Daniel Rueckert
arXiv Machine Learning
Jul 16

A novel unsupervised machine learning strategy to handle multimodal cardiac PET/MRI data

arXiv:2607. 13936v1 Announce Type: cross Abstract: Arrhythmogenic left ventricular cardiomyopathy is a genetic myocardial disease difficult to diagnose due to the lack of gold standard criteria.

By Brunnhilde Ponsi (Nantes Universit\'e, CHU Nantes, Nantes, France, CRCI2NA, INSERM UMR 1307, Nantes, France), Thomas Carlier (Nantes Universit\'e, CHU Nantes, Nantes, France, CRCI2NA, INSERM UMR 1307, Nantes, France), Lara Marteau (Nantes Universit\'e, CHU Nantes, Nantes, France, Cardiology Department, INSERM UMR 1307, CIC 1413, l'institut du Thorax, Nantes, France), Aur\'elien Monnet (Siemens Healthineers France, Courbevoie, France), Thomas Eug\`ene (Nantes Universit\'e, CHU Nantes, Nantes, France, CRCI2NA, INSERM UMR 1307, Nantes, France), Jean-Michel Serfaty (Nantes Universit\'e, CHU Nantes, Nantes, France, Radiology Department, l'institut du Thorax, Nantes, France), Nicolas Piriou (Nantes Universit\'e, CHU Nantes, Nantes, France, Cardiology Department, INSERM UMR 1307, CIC 1413, l'institut du Thorax, Nantes, France), Hatem Necib (Nantes Universit\'e, CHU Nantes, Nantes, France, CRCI2NA, INSERM UMR 1307, Nantes, France)
arXiv Computer Vision
Sep 1

The MYOSAIQ Challenge: Myocardial Segmentation with Automated Infarct Quantification

arXiv:2608.29246v1 Announce Type: cross Abstract: Late gadolinium enhancement (LGE) cardiac magnetic resonance (MR) imaging is the modality of choice to assess myocardial infarction (MI) lesions. Now...

By Olivier Bernard, William A. Romero R., Cyprien Bouton, Celia Goujat, Hang Jung Ling, Pierre-Marc Jodoin, Fumin Guo, Calder Sheagren, Graham Wright, Abdul Qayyum, Moona Mazher, Steven A. Niederer, Hairui Wang, Xiaomei Wu, Franz Thaler, Gernot Plank, Martin Urschler, Ricardo M. Rosales, Esther Pueyo, Nicolas Duchateau, Frederic Cervenansky, Patrick Clarysse, Loic Belle, Thomas Bochaton, Nathan Mewton, Magalie Viallon, Pierre Croisille
arXiv AI
2d ago

CineMR: Tool-Integrated Vision-Language Reasoning for Quantitative Cardiac MRI Assessment

arXiv:2610.01166v1 Announce Type: cross Abstract: Cardiovascular magnetic resonance (CMR), including cine imaging, is a reference standard for the noninvasive assessment of cardiac morphology and ven...

By Kunyang Li, Hai Nguyen, Joshua Lowe, Chenguang Zhao, Peace C. Madueme, Mehdi Hedjazi Moghari, Mubarak Shah, Pegah Khosravi, Yuzhang Zhang
arXiv Computer Vision
Sep 14

SV-Cine: Diagnosis-Conditioned Segmentation of Single Ventricle Physiology via Generative Data Augmentation

The paper introduces SV-Cine, a cardiac MRI segmentation framework tailored for single ventricle physiology (SVP). It combines a generative data augmentation pipeline that creates synthetic 3D cardiac meshes and MRI, with a diagnosis-conditioned adaptation of the CineMA foundation model that uses patient-level diagnostic information to improve segmentation. Evaluations on an internal cohort show high Dice scores for left and right ventricles, outperforming nnU-Net, and demonstrate that incorporating diagnosis priors can adapt a pretrained model to specialized SVP tasks.

By Lila Cunge, Yuehong Liu, Hang Xu, Thomas Coudert, Pierangelo Renella, J Paul Finn, William Hsu, Kim-Lien Nguyen
arXiv Machine Learning
Jul 14

Artificial Intelligence Across the Cardiac Amyloidosis Diagnostic Pathway: From Single-Modality Detection to Multimodal Clinical Integration

arXiv:2607. 09948v1 Announce Type: cross Abstract: Cardiac amyloidosis (CA) is increasingly recognized but remains substantially underdiagnosed, because its clinical and imaging phenotype overlaps with more common cardiomyopathies.

By Diana Shadibaeva, Rochak Dhakal, Kui Zhang, Xiaofeng Yang, Saurabh Malhotra, Weihua Zhou
arXiv Computer Vision
Aug 24

Toward Vision Language Model-based Assessment of Clinical Quality and Usability of LGE-MR Images for Cardiac Ablation Planning

This study introduces a two‑stage vision‑language model framework to assess the clinical quality and usability of late gadolinium enhancement (LGE) cardiac MRI images used for atrial fibrillation ablation planning. The first stage employs a fine‑tuned VLM to generate structured radiology‑style reports on five quality criteria—Noise, Motion Artifact, LA Boundary Accuracy, PV Region Accuracy, and Under‑segmentation Severity—while the second stage uses a GPT‑based reasoning module to convert these reports into structured quality scores and a binary decision on clinical usability. Evaluated on a curated dataset of 60 image‑slice and text‑pair annotations from 20 patients, the InternVL2 model achieved the highest criterion‑level accuracy, and DeepSeek reached perfect agreement on the clinical usability decision.

By Bipasha Kundu, Abhishek Chaturvedi, Axel W. E. Wismueller, Richard Simon, Cristian A. Linte
arXiv Machine Learning
Jul 21

ECG-LLM: Foundation Model for ECG-Based Cardiac Reasoning

arXiv:2607. 16323v1 Announce Type: cross Abstract: Electrocardiography (ECG) is an inexpensive, standard-of-care test for cardiac symptoms, but front-line triage often lacks immediate access to definitive imaging such as echocardiography (ECHO) or cardiac magnetic resonance (CMR).

By Alexander Selivanov, Friederike Jungmann, Jan Kehrer, Karl-Ludwig Laugwitz, Eimo Martens, Daniel Rueckert
arXiv AI
Sep 10

Leveraging Cardiac Imaging to Improve ECG-Based Detection of Chagas Disease in Resource-Constrained Settings

The study demonstrates that contrastive pre‑training of ECG representations using cardiac magnetic resonance (CMR) imaging data can enhance ECG‑based detection of Chagas disease. By aligning an ECG encoder with a CMR embedding space from 63,193 paired UK Biobank examinations, the authors achieved higher AUROC and sensitivity metrics on CODE‑15%, SaMi‑Trop, and PhysioNet/CinC 2025 Challenge datasets compared to an unaligned baseline. The approach shows that imaging‑supervised ECG representations generalize across different populations and resource‑constrained settings.

By Laura Alvarez-Florez, Daniel Uyterlinde, Samuel Ruip\'erez-Campillo, Lukas P. A. Arts, Folkert W. Asselbergs, Fleur V. Y. Tjong