arXiv AI

MedStruct-S: A Benchmark for Key Discovery, Key-Conditioned QA and Semi-Structured Extraction from OCR Clinical Reports

MedStruct‑S is a benchmark for semi‑structured information extraction from OCR‑derived clinical reports, covering key discovery, key‑conditioned QA, and end‑to‑end key‑value extraction. It contains 3,582 annotated real‑world report pages and evaluates models under unknown keys and OCR noise. Experiments show encoder‑only models excel at non‑null key‑conditioned QA, while fine‑tuned decoder‑only models achieve the strongest overall performance across model sizes.

arXiv AI
Aug 20

Key Coverage Matters: Semi-Structured Extraction of OCR Clinical Reports

The paper presents a method for extracting key information from OCR‑digitized clinical reports, addressing challenges posed by heterogeneous documents and noisy OCR output. It introduces an open key space that is iteratively mined, normalized, clustered, and verified to build a canonical key inventory, and defines key coverage as a metric for inventory completeness. Experiments on reports from over 20 hospitals using a 0.2B BERT model show that performance improves steadily with key coverage, achieving high F1 scores when the top 90 keys are covered and outperforming a fine‑tuned Qwen3‑0.6B baseline.

By Yu Wang, Yingyun Li, Ying Qin, Haiyang Qian
arXiv AI
Sep 25

A Living Benchmark for Information Retrieval from Electronic Health Records

The paper introduces BRIE, a continuously maintainable benchmark for evaluating large language models (LLMs) in electronic health record (EHR) information retrieval. It presents a scalable framework that automatically generates question–answer pairs from longitudinal EHR notes, validated by nineteen clinicians. The benchmark allows assessment of multiple inference strategies and highlights that state‑of‑the‑art LLMs often miss clinically important information, especially when synthesis across documents is required.

By Jordan L. Cahoon, Chloe O. Stanwyck, Sulaiman Somani, Philip Chung, Kevin R Keet, Kameron C. Black, Andrea T. Fisher, Sarita Khemani, Jerry Liu, Stephen Ma, Saloni K. Maharaj, Rita M. Pandya, Eduardo Perez-Guerrero, Priyanka Pillai, Lisa Shieh, David J. H. Wu, James Xie, James C. McAvoy, Teresa Nguyen, Jessica Tran, Lucy Yin, Bridget Lin, Alison Callahan, Jason A. Fries, Nigam H. Shah, Emily Alsentzer
Hugging Face Trending Papers
Sep 24

A Living Benchmark for Information Retrieval from Electronic Health Records

The paper introduces BRIE, a scalable framework that automatically creates question–answer pairs from longitudinal electronic health record notes, validated by nineteen clinicians. It offers a continuously maintainable benchmark for evaluating large language models in clinical settings, addressing limitations of manual, costly, and quickly outdated existing benchmarks. Experiments across nine LLMs and five inference strategies reveal that even state‑of‑the‑art systems often miss clinically important information, especially for synthesis‑heavy queries.

arXiv AI
Jun 30

Primary ICD Category Prediction using LLM-based Probing

arXiv:2606. 28798v1 Announce Type: new Abstract: Objective: ICD codes are central to reimbursement, research, and population health surveillance, yet automated coding systems often struggle to integrate diagnostic signals from both clinical narratives and structured electronic health record (EHR) variables.

By Chengyuan Liu, Xinyue Zhang, Yao Li, Guanting Chen
arXiv AI
Jul 13

Evaluating Retrieval-Augmented Generation vs. Long-Context Input for Clinical Reasoning over EHRs

arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).

By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar
arXiv Machine Learning
Aug 21

Explainable Transformer Models for Clinical Prediction Tasks on Structured Electronic Health Records

arXiv:2608. 20315v1 Announce Type: new Abstract: Predictive models over structured electronic health records (EHRs) remain central to machine learning for healthcare, but few have jointly emphasized quantitative laboratory information and interpretability with respect to input medical events.

By Jun Ni Du, Lukas Adamek, Maxim Kryukov, Flavio Dormont, Ziv Bar-Joseph, Sven Jager, Brandon Rufino
arXiv Computation and Language
Oct 16

MeddeX: A Retrieval-Augmented LLaMA-3 System with Gemini Vision for Evidence-Backed Medical Report Analysis

MeddeX is a medical report analyzer that fuses a QLoRA‑fine‑tuned LLaMA‑3 (8B) model with Retrieval‑Augmented Generation and a Gemini Vision layer to produce concise, evidence‑backed summaries of medical documents. It processes text‑native PDFs, scanned PDFs, and radiological images via a hybrid extraction pipeline featuring a garbage‑text detection mechanism for corrupted or UTF‑16‑encoded files. The system adds report‑scoped retrieval, an automated longitudinal comparison engine, and a self‑healing backfill pipeline, and is backed by a FastAPI backend, Supabase vector store, and Next.js frontend. Evaluation shows significant gains over the base LLaMA‑3‑Med42‑8B model across ROUGE, BLEU, and BERTScore metrics, underscoring the value of domain‑specific fine‑tuning.

By Rajdeep Pandhare, Rohit Kundaikar, Yakub Kojar, Shreyansh Tiwari
arXiv AI
Jul 9

Health System Scale Semantic Search Across Unstructured Clinical Notes

arXiv:2604. 25605v2 Announce Type: replace-cross Abstract: Introduction: Semantic search, which retrieves documents based on conceptual similarity rather than keywords, offers advantages for retrieval of clinical information.

By Faith Wavinya Mutinda, Spandana Makeneni, Anna Lin, Shivaji Dutta, Irit R. Rasooly, Patrick Dibussolo, Shivani Kamath Belman, Hessam Shahriari, Kevin Murphy, Alex B. Ruan, Barbara H. Chaiyachati, Sanjay Chainani, Robert W. Grundmeier, Scott M. Haag, Jeffrey M. Miller, Heather M. Griffis, Ian M. Campbell
arXiv AI
Oct 5

RASPER: Reward-Aligned Summarization of Clinical Notes for EHR Outcome Prediction

RASPER is a reward‑aligned summarizer that tailors the extraction of information from unstructured discharge notes to improve downstream clinical predictions. It uses a tunable LLM summarizer trained with reinforcement learning, where the reward comes from the loss of a downstream predictor, and incorporates patient‑specific context via a longitudinal encoder that soft‑prompts the summarizer with structured codes. The approach consistently outperforms strong baselines on readmission prediction and medication recommendation tasks in the MIMIC‑III and MIMIC‑IV datasets.

By Arya Hadizadeh Moghaddam, Mohsen Nayebi Kerdabadi, Chen Chen, Dongjie Wang, Zijun Yao
arXiv Machine Learning
Jun 24

PORTER: Language-Grounded Event Representations for Portable Structured EHR Foundation Models

arXiv:2606. 24102v1 Announce Type: cross Abstract: Most electronic health record (EHR) foundation models encode clinical events as discrete event tokens from a fixed vocabulary and therefore cannot directly represent events containing unseen concepts or new combinations of concepts and attributes such as numeric values.

By Lin Lawrence Guo, Adam Paul Yan, Emily Vettese, Lillian Sung
arXiv AI
Jun 16

EHRNote-ChatQA: A Benchmark for Evidence-Grounded Multi-Turn Clinical Question Answering over Longitudinal Discharge Summaries

arXiv:2606. 15735v1 Announce Type: cross Abstract: Discharge summaries are crucial clinical documents containing the context of a patient's overall hospital stay, and are routinely reviewed by medical experts for patient readmission, ongoing care, and diagnostic decision-making.

By Jiyoun Kim, Muhan Yeo, Eunhye Jang, Jeewon Yang, Hangyul Yoon, Su Ji Lee, Hee Jo Han, Hee-Jae Jung, Doyun Kwon, Jun young Lee, Jaehun Lee, Jung-Oh Lee, Sunjun Kweon, Jong Hak Moon, Daseul Kim, Minjae Cho, Edward Choi