arXiv AI

RASPER: Reward-Aligned Summarization of Clinical Notes for EHR Outcome Prediction

RASPER is a reward‑aligned summarizer that tailors the extraction of information from unstructured discharge notes to improve downstream clinical predictions. It uses a tunable LLM summarizer trained with reinforcement learning, where the reward comes from the loss of a downstream predictor, and incorporates patient‑specific context via a longitudinal encoder that soft‑prompts the summarizer with structured codes. The approach consistently outperforms strong baselines on readmission prediction and medication recommendation tasks in the MIMIC‑III and MIMIC‑IV datasets.

arXiv AI
Jun 3

ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).

By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li
arXiv Machine Learning
4d ago

GLoC-EHR: Evidence-Cited Clinical Reasoning over Global Context and Local EHR Events

GLoC-EHR is a multimodal language model that processes electronic health records by combining a fixed-size global memory of the entire patient trajectory with a local memory of selected events. It generates hospital-course summaries and masked concept descriptions, then is fine‑tuned to cite evidence before answering clinical questions, using group relative policy optimization to reward correct, evidence‑supported responses. On MIMIC‑IV outcome tasks, GLoC‑EHR achieves the highest macro AUROC among compared models when answering directly, and maintains strong performance with evidence‑cited reasoning while adding distinct supported findings from the local memory.

By Chaiho Shin, Kwangsoo Kim
arXiv Machine Learning
Aug 4

EHR2Path: Comprehensive Pathway-Level Modeling of Longitudinal Patient Trajectories from Multimodal Electronic Health Records

arXiv:2506. 04831v3 Announce Type: replace Abstract: Forecasting how a patient's condition is likely to evolve, including possible deterioration, recovery, treatment needs, and care transitions, could support more proactive and personalized care, but requires modeling heterogeneous and longitudinal electronic health record (EHR) data.

By Chantal Pellegrini, Ege \"Ozsoy, David Bani-Harouni, Matthias Keicher, Nassir Navab
arXiv Computation and Language
Sep 22

Knowledge Graph-Augmented Ambient AI for Clinical Note Generation

arXiv:2609.22239v1 Announce Type: new Abstract: Ambient AI is increasingly adopted in healthcare to automatically generate clinical notes from patient-clinician conversations, with the potential to s...

By Jakir Hossain, Yi-Fei Zhao, Hongjian Wang, Minmei Shih, Katie Leigh Mullen, Ahmad P. Tafti, Leming Zhou, Manoj Purohit, William Hogan, Jay Zeng, Elizabeth Skidmore, Yanshan Wang
arXiv Machine Learning
Aug 21

Explainable Transformer Models for Clinical Prediction Tasks on Structured Electronic Health Records

arXiv:2608. 20315v1 Announce Type: new Abstract: Predictive models over structured electronic health records (EHRs) remain central to machine learning for healthcare, but few have jointly emphasized quantitative laboratory information and interpretability with respect to input medical events.

By Jun Ni Du, Lukas Adamek, Maxim Kryukov, Flavio Dormont, Ziv Bar-Joseph, Sven Jager, Brandon Rufino
arXiv AI
Jul 13

Evaluating Retrieval-Augmented Generation vs. Long-Context Input for Clinical Reasoning over EHRs

arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).

By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar