arXiv:2609.26463v1 Announce Type: new
Abstract: Accurate preoperative subtype classification of renal cell carcinoma (RCC) from contrast-enhanced computed tomography remains clinically challenging. R...
By Yuan Liang, Sourav Bhattacharjee, Abraham Campbell
arXiv:2609.26578v1 Announce Type: new
Abstract: Accurate preoperative subtype classification of renal cell carcinoma (RCC) from contrast-enhanced CT remains clinically challenging because clear cell...
By Yuan Liang, Fangyijie Wang, Kathleen M. Curran, Gu\'enol\'e Silvestre, Sourav Bhattacharjee, Abraham Campbell
arXiv:2610.14152v1 Announce Type: cross
Abstract: Gate coefficients describe how a fusion layer weights intermediate features, but they do not necessarily reflect the magnitude of branch contribution...
By Yuan Liang, Sourav Bhattacharjee, Abraham Campbell
arXiv:2609.26492v1 Announce Type: new
Abstract: Radiomics provides quantitative descriptions of tumour appearance that may complement disease-specific foundation models in small labelled cohorts. We...
By Yuan Liang, Sourav Bhattacharjee, Abraham Campbell
Clear cell renal cell carcinoma (CCRCC) grading is essential for treatment planning, yet existing approaches either analyze patch-level images directly or focus solely on nuclei-level classification,...
The paper introduces a semantic‑guided multimodal preprocessing technique that fuses nuclei classification maps with RGB histopathology images for Vision Transformer‑based grading of clear cell renal cell carcinoma. By concatenating classification map channels and applying multiplicative modulation, the method achieves a balanced accuracy of 0.916, markedly surpassing an RGB‑only baseline (0.707) and prior max‑voting approaches (0.427). Sensitivity analysis shows the 21‑percentage‑point improvement remains robust under simulated perturbations matching current nuclei classifier error rates, indicating effective use of imperfect nuclear‑level information.
By Fatemeh Javadian, Zhu Chen, Zahra Aminparast, Johannes Stegmaier
arXiv:2608. 11472v1 Announce Type: cross Abstract: Pancreatic cancer is among the most lethal malignancies; risk stratification of intraductal papillary mucinous neoplasms (IPMNs) offers a crucial opportunity for early intervention but typically requires invasive tissue biopsy.
By Max A. Nelson, Eminenur Sen Tasci, Zhixiang Wang, Zongwei Zhou, Halil Ertugrul Aktas, Andrea M. Bejar, Elif Keles, Ziliang Hong, S{\i}tk{\i} Safa Taflan, Muhammed Enes Tasci, Frank H. Miller, Michael B. Wallace, Rajesh N. Keswani, Gorkem Durak, Ulas Bagci
The study introduces RCC-Align, a cross‑modal contrastive learning framework that aligns paired histopathology whole‑slide images and CT scans to enhance noninvasive grading of clear cell renal cell carcinoma (ccRCC). Using patient‑level five‑fold cross‑validation on TCGA and CPTAC cohorts, RCC‑Align achieved an AUC of 0.601 and AUPRC of 0.599 for low‑ versus high‑grade ccRCC classification, outperforming CT‑only baselines and showing stronger WSI‑CT embedding alignment. The approach relies solely on CT at inference, potentially aiding grading when biopsy is unsafe or limited by tumor heterogeneity.
By Amit Das, Tanmay Shukla, Naofumi Tomita, Faraz Farhadi, Jessica Sin, Ari Hakimi, Chad Vanderbilt, Jie-Fu Chen, Ritesh Kotecha, Weijie Ma, Bing Ren, Saeed Hassanpour
arXiv:2607. 04478v1 Announce Type: cross Abstract: Automated chest X-ray classification remains challenging due to severe class imbalance, co-occurring pathologies, and the loss of localized features in conventional architectures.
By Moshiur Rahman, Shafqat Alam, Tasnia Binte Mamun
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti
arXiv:2609.09189v1 Announce Type: cross
Abstract: High classification accuracy alone is insufficient for clinical image analysis, where calibrated confidence and reliable uncertainty estimates are es...
By Nisreen Albzour, Sarah S. Lam
arXiv:2607. 12075v1 Announce Type: cross Abstract: Background: Deep learning models can classify thyroid nodules on ultrasound, but reliable clinical decision support also requires calibrated probabilities, uncertainty estimation, and selective referral, particularly under dataset shift.
By Md. Sadibul Hasan Sadib, Md. Mohayminul Mukit, Rahmatul Kabir Rasel Sarker, Tahmid Alam Tamim, Md. Monir Hossain Shimul