arXiv Machine Learning

Disentangling Latent Risk Pathways via Bayesian Hypergraph Inference

arXiv:2606. 07677v1 Announce Type: cross Abstract: Electronic health records (EHR) pose large-scale multi-disease modeling problems in which many outcomes are rare and strongly influenced by shared risk factors.

arXiv Machine Learning
Aug 26

A Structural FHMM for Interpretable Disease Trajectories in T2DM

arXiv:2608.24328v1 Announce Type: new Abstract: In this work, we propose a structural variant of the Factorial Hidden Markov Model (FHMM) for the analysis of disease trajectories in patients with Typ...

By Alessandro Mari, Ekaterina Krymova, Guillaume Obozinski, Maria Luisa Marques de Sa Faquetti, Adrian Martinez de la Torre, Andrea Burden
arXiv Machine Learning
Sep 15

Scalable partial information decomposition for symptom networks via supervised embeddings

The paper introduces ePID, an embedding-based approach that scales partial information decomposition (PID) to large symptom networks by compressing non‑focal symptoms into a low‑cardinality discrete embedding. Using a supervised Agglomerative Conditional Information Bottleneck (ACIB) embedding, ePID accurately recovers source‑unique, remainder‑unique, redundant, and synergistic components for each ordered source‑target pair across 83 real‑world datasets, outperforming 12 other embeddings. Applied to PHQ‑9 and the Interpersonal Reactivity Index, ePID reveals distinct patterns of redundancy and synergy that align with each instrument’s construction, demonstrating its ability to separate overlapping from interaction‑dependent information in symptom networks.

By Cillian Hourican, Eric Dignum, Rick Quax, Debraj Roy
arXiv Machine Learning
Jun 9

Causal Representation Learning from Network Data

arXiv:2509. 01916v2 Announce Type: replace Abstract: Causal disentanglement from soft interventions is identifiable under the assumptions of linear interventional faithfulness and availability of both observational and interventional data.

By Jifan Zhang, Michelle M. Li, Elena Zheleva
arXiv Machine Learning
Jun 11

Enhancing Spectral Embedding through Robust and Flexible Knowledge Transfer in Electronic Health Records

arXiv:2606. 11570v1 Announce Type: cross Abstract: We propose a spectral-based, unsupervised representation learning framework to derive low-dimensional embeddings for clinical concepts and patients in rare disease cohorts from electronic health records, where data are high-dimensional but sample sizes are limited.

By Feiqing Huang, Zongqi Xia, Rong Ma, Tianxi Cai