arXiv Machine Learning

A Bayesian Boolean Matrix Factorization with Application to Copy Number Analysis in Cancer

arXiv:2606. 17491v1 Announce Type: cross Abstract: Binary data factorization is common, but real-valued methods ignore discreteness and yield hard-to-interpret factors.

arXiv Machine Learning
Jul 16

Multimodal Empirical Bayes Variational Autoencoders for Joint Longitudinal and Time-to-Event Modeling

arXiv:2607. 13984v1 Announce Type: cross Abstract: Longitudinal tumor measurements, dropout information, and genetic covariates provide complementary information about treatment response, but integrating these data sources within a single population modeling framework remains challenging.

By Anders Sj\"oberg, Nils Olsson, Marcus Baaz, Mats Jirstrand
arXiv AI
Jun 12

Is It You or Your Environment? A Bayesian Inference Framework for Genomically-Anchored Personalized Physiological Interpretation

arXiv:2606. 13556v1 Announce Type: new Abstract: Personalized health AI systems face a fundamental cold-start problem: machine learning models for physiological interpretation require weeks of individual behavioral data before they can distinguish constitutional variation from environmentally driven deviation.

By Aruna Dey, Suraj Biswas
arXiv Machine Learning
Jun 11

Seeing Below the Limit of Detection: A Censored-Poisson Bayesian Latent-Growth Change-Point Detector (the Span Detector) for Serial ctDNA in HR+/HER2- Metastatic Breast Cancer

arXiv:2606. 11876v1 Announce Type: cross Abstract: Circulating-tumour DNA (ctDNA) carries evidence of drug resistance months before imaging shows it, but the earliest evidence lives below the assay's limit of detection (LoD): a nascent subclone is detected only intermittently, producing a flickering sequence of faint detects and non-detects.

By Aarchi Singh Thakur, Abhijoy Sarkar
arXiv AI
Jul 14

CDFM: Towards a General-Purpose Causal Discovery Foundation Model

arXiv:2607. 11508v1 Announce Type: cross Abstract: Causal discovery, the process of recovering underlying causal structures from observational data, is a fundamental pursuit across scientific disciplines.

By Jie Qiao, Ruichu Cai, Zijian Li, Weilin Chen, Pengfei Hua, Boyan Xu, Zhengming Chen, Zhifeng Hao, Peng Cui
arXiv AI
Jul 23

Causal dictionary learning reveals and validates transcription-factor binding features in genomic language models

arXiv:2607. 19618v1 Announce Type: cross Abstract: Genomic language models achieve strong performance across regulatory-genomics tasks, yet what these models internally represent remains opaque, and the field lacks a principled procedure for verifying that an apparent ``concept'' inside a model is real rather than an artifact of sequence composition.

By Sarwan Ali