arXiv:2606. 07368v1 Announce Type: cross Abstract: Automated mitosis detection is a well-established task in computational pathology.
Mitotic figure (MF) analysis supports tumor grading and prognostic assessment, but automated models remain sensitive to differences in tissue type and image acquisition. We present MiTHras, a task-spe...
The study introduces MitPro, an AI tool that guides pathologists to regions with high mitotic activity and highlights mitotic figures, aiming to reduce variability and time in tumour grading. In a retrospective paired reader study of 385 whole‑slide images across seven tumour types, AI assistance raised the intraclass correlation coefficient from 0.589 to 0.949 and cut median assessment time from 286.4 to 127.8 seconds. The tool also produced a slight increase in mitotic counts, aligning with the detection of more active hotspots, while the frequency of score changes matched typical inter‑pathologist variation.
The paper introduces CoPath, a lightweight framework for diagnosing peripheral neuroblastic tumors (pNTs) from whole-slide images. CoPath combines CoHisNet, a multi‑scale feature‑fusion network that replaces traditional MLPs with Kolmogorov‑Arnold Network layers for efficient nonlinear modeling, and PathVote, which aggregates patch‑level predictions using pathology‑informed priors. Experiments on a private pNT cohort and the public BreakHis dataset show that CoPath matches or surpasses existing classifiers while reducing computational complexity.
arXiv:2609.24736v1 Announce Type: cross Abstract: Mitotic figure (MF) analysis supports tumor grading and prognostic assessment, but automated models remain sensitive to differences in tissue type an...
arXiv:2606. 12346v1 Announce Type: cross Abstract: Hematoxylin and eosin (H&E) staining is the cornerstone of histopathology, yet scalable, quantitative analysis of H&E whole-slide images (WSIs) remains a central challenge in computational pathology.
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
arXiv:2607. 00385v1 Announce Type: cross Abstract: Automated malaria diagnosis from blood smear microscopy is a critical challenge in global health AI; in resource-limited settings, the scarcity of expert microscopists remains the primary bottleneck to timely and accurate diagnosis.
arXiv:2609.00704v1 Announce Type: new Abstract: Functional tissue units (FTUs), including tertiary lymphoid structures (TLSs), blood vessels, and glands, encode localized immune, vascular, and epithe...
arXiv:2607. 00385v2 Announce Type: replace-cross Abstract: Automated malaria diagnosis from blood smear microscopy is a critical global health AI challenge; expert scarcity remains the primary diagnostic bottleneck.
The paper introduces a dual‑input, multi‑task learning framework that jointly segments and classifies bone tumors by applying bidirectional cross‑modal attention between a lesion crop and the full radiograph. Using a YOLO‑based detector and a dual‑stream DenseNet121 architecture, the model fuses fine‑grained lesion detail with global anatomical context through a novel cross‑modal attention fusion strategy and hierarchical multi‑scale feature fusion. On the multi‑institutional Bone Tumor X‑ray Radiograph Dataset, the approach outperforms single‑input baselines, achieving a Dice coefficient of 0.896 and a macro‑averaged F1‑score of 0.928, with an AUC of 0.999 for malignant osteosarcoma.
RACR-MIL is a weakly‑supervised method for grading squamous cell carcinoma (SCC) from whole‑slide images, using an attention‑based multiple‑instance learning framework. It introduces a hybrid WSI graph to capture local tissue context and non‑local phenotypic dependencies, and applies rank‑ordering constraints on attention to prioritize higher‑grade tumor regions, mirroring pathologists’ diagnostic reasoning. The approach achieves state‑of‑the‑art performance, improving SCC grading accuracy by 3–9% over existing methods and up to 10% in tumor localization, and a pilot study showed pathologists reported increased grading efficiency in 60% of cases.
arXiv:2602. 02124v2 Announce Type: replace-cross Abstract: Drug-induced toxicity is a leading cause of preclinical and early-clinical failure, making early detection critical.