arXiv AI

NeuroRefiner: Morphology-Aware Multi-Agent Refinement for 3D Fluorescence Microscopy Neuron Segmentation

arXiv:2608. 09636v1 Announce Type: cross Abstract: Accurate 3D neuron segmentation in fluorescence microscopy is critical for neuroscience.

arXiv Computer Vision
Aug 27

Steer the Sampling, Not the Kernel Grid: Geometry-Guided Sampling Operator for Volumetric Segmentation

The paper introduces a geometry‑guided sampling operator that directs feature sampling rather than altering convolution kernels in 3D encoder‑decoder networks. By predicting local orientations and bounded step sizes, the operator samples symmetrically around each voxel, generating compact geometric and boundary cues that improve fine‑structure segmentation. Replacing stride‑1 and stride‑2 operations in a 3D U‑Net yields consistent gains on BraTS, MSD Hepatic Vessel, and TDSC‑ABUS datasets, with better boundary metrics and fewer parameters, and the operator can be integrated into other backbones without architectural changes.

By Sizhe Wang, Himashi Peiris, Zhaolin Chen
arXiv AI
Sep 25

A Multimodal 3D Foundation Model for Light Sheet Fluorescence Microscopy Enables Few-Shot Segmentation, Classification, and Deblurring

The paper presents a 3D foundation model for light sheet fluorescence microscopy (LSM) that is pretrained on a large curated set of 3D images from various organisms, stains, and imaging protocols. By jointly optimizing for masked reconstruction and image‑text alignment, the model learns transferable volumetric representations that dramatically reduce the need for annotated data. The pretrained backbone enables efficient few‑shot adaptation to downstream tasks such as segmentation, classification, and deblurring, consistently outperforming baselines according to standard metrics and expert evaluation.

By Adina Scheinfeld, Haotan Zhang, Shang Mu, Rudolf L. M. van Herten, Lucas Stoffl, Ali Erturk, Zhuhao Wu, Johannes C. Paetzold
arXiv Machine Learning
Sep 16

NeuroTS-Net: Multi-Class Semantic Segmentation of Pediatric Brain Tumors in Multi-Modal MRI

NeuroTS-Net is a 3‑D encoder‑decoder CNN designed for multi‑class semantic segmentation of pediatric brain tumors in multi‑modal MRI. It uses a dual‑scale raw‑detail stream, adaptive low‑resolution context selection, and detail‑preserving multipath downsampling to maintain fine intensity and boundary information while modeling broader tumor context. Trained on the BraTS 2026 pediatric dataset, it outperformed nnU‑Net and MedNeXt, achieving Dice scores of 0.938/0.937 on internal validation and 0.927/0.926 on the official challenge set.

By Darius Peteleaza, Razvan-Gabriel Dumitru, Bogdan Neamtu, Arpad Gellert, Mariana Sandu, Claudiu Matei