arXiv AI By Iker Moran-Cavero, Monica Hernandez, Elvira Mayordomo, Naiara Artiaga, Beatriz Pardi\~nas, Beatriz Cordon, Elena Garcia-Martin

Spatial Normalization for Cross-Domain Retinal Layer Segmentation in Optical Coherence Tomography

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arXiv:2607. 16065v1 Announce Type: cross Abstract: Retinal layer segmentation in Optical Coherence Tomography (OCT) is a fundamental step for extracting quantitative biomarkers of retinal structure.

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arXiv AI
Aug 3

DualDiT: A Conditional Dual-Output Diffusion Transformer for Joint OCT Image and Segmentation Mask Generation

arXiv:2607. 29337v1 Announce Type: cross Abstract: Background and Objective: Generating realistic medical images with anatomically accurate segmentation masks helps address the shortage of annotated data in medical imaging, particularly in optical coherence tomography (OCT) of mouse eyes, where manual retinal layer delineation is labour-intensive due to tiny structures and required expertise, resulting in scarce datasets.

By Fernando Garc\'ia-Torres, Roc\'io del Amor, Sandra Morales, \'Alvaro Barroso, Peter Heiduschka, Bj\"orn Kemper, Valery Naranjo
arXiv Computer Vision
Aug 28

Automated 2D and 3D Segmentation of AMD and DME Lesions in OCT

This study presents four deep‑learning pipelines—two‑dimensional and three‑dimensional—for segmenting age‑related macular degeneration (AMD) and diabetic macular edema (DME) lesions in optical coherence tomography (OCT) images. The models achieve Dice scores between 0.76 and 0.82 and demonstrate strong volumetric and surface calibration (r_vol, r_surf ≥ 0.97) on an in‑domain validation set. Generalization was assessed on the OLIVES clinical cohort using proxy metrics such as biomarker AUROC, central subfield thickness correlation, and longitudinal concordance, showing that the predictions still track clinical biomarkers outside the training distribution, albeit with reduced strength.

By Lucia Sundberg, Zhihao Zhao, M. Ali Nasseri
arXiv Computer Vision
6d ago

Cross-Modality Structural Guidance in 3D Latent Diffusion for Robust FLAIR Super-Resolution

The paper introduces MR‑DiffuSR, a 3‑D latent diffusion framework that uses high‑resolution T1w structural priors to guide super‑resolution of thick‑slice FLAIR MRI scans. By applying cross‑modality structural swin attention and a mixed‑scale degradation strategy, the method avoids hallucinations and remains robust across varying slice thicknesses. On ADNI datasets, MR‑DiffuSR outperforms CNN and 2‑D diffusion baselines, achieving high PSNR, SSIM, and low LPIPS, and maintains strong white‑matter hyperintensity segmentation performance even at 7 mm equivalent slice thickness.

By Haoyu Lan, Jiazhen Zhang, John Onofrey, Bino Varghese, Nasim Sheikh-Bahaei, Arthur W. Toga, Jeiran Choupan