arXiv Computation and Language

Language Impairment as a Lens onto Large Language Models

The paper introduces a mechanistic interpretability framework inspired by aphasia to probe large language models (LLMs). Using classifier‑guided lesioning and continuous activation steering, the authors induce aphasia‑like breakdowns and find that language functions can be isolated to discrete structural circuits and continuous vectors, yet these functions are densely entangled with significant overlap across different aphasic profiles. While steering generalizes across downstream tasks, structural lesioning shows asymmetric constraints, highlighting the densely entangled architecture of LLMs that can be mapped through clinically‑informed interventions.

arXiv Machine Learning
Aug 14

Perturbation-based Regional Interpretability through Subtraction Mapping (PRISM): naming-error dissociations in language models and post-stroke aphasia

arXiv:2608. 12717v1 Announce Type: new Abstract: Mechanistic interpretability of large language models lacks spatially resolved, falsifiable tools for testing whether internal components are specialized for distinct cognitive operations.

By Xiang Guan, Roger D. Newman-Norlund, Yong Yang, Saeed Ahmadi, Regan Willis, Nadra Salman, Kalil Warren, Srihari Nelakuditi, Chris Rorden, Leonardo Bonilha, Julius Fridriksson
arXiv Computation and Language
Oct 21

Can Language Models Get "Aphasia" From Neuronal Ablation?

The study investigates how progressive neuronal loss affects language models by systematically ablating computational units in LSTM and Transformer architectures. LSTMs show a gradual decline in syntactic and semantic abilities, while Transformers exhibit a threshold-like collapse under MLP ablation and a smoother sigmoid-like decline under attention-head ablation. These distinct failure modes mirror different aphasic syndromes, suggesting that architecture-dependent degradation patterns can provide computational insights into neurodegenerative diseases.

By Pratik Worah, Randall Bateman
arXiv AI
Jun 2

A Monosemantic Attribution Framework for Stable Interpretability in Clinical Neuroscience Transformer-Based Language Models

arXiv:2601. 17952v2 Announce Type: replace-cross Abstract: Interpretability remains a key challenge for deploying language models (LM) in clinical settings such as progression diagnosis of Alzheimer disease, where early and trustworthy predictions are essential.

By Michail Mamalakis, Tiago Azevedo, Cristian Cosentino, Chiara D'Ercoli, Subati Abulikemu, Zhongtian Sun, Richard Bethlehem, Pietro Lio
arXiv Machine Learning
Aug 10

Recovering Lesion Parameters from Aphasic Picture Naming Error Profiles in Large Language Models

arXiv:2608. 06429v1 Announce Type: cross Abstract: Interpretability methods for large language models (LLMs) describe internal state but do not directly test whether that state is causally sufficient to produce the observed behavior.

By Yong Yang, Roger Newman-Norlund, Xiang Guan, Saeed Ahmadi, Regan Willis, Nadra Salman, Kalil Warren, Sophie Arheix-Parras, Srihari Nelakuditi, Leonardo Bonilha, Christopher Rorden, Rutvik H. Desai, Julius Fridriksson
arXiv AI
Jul 2

NeuroCogMap Reveals Cognitive Organization of Large Language Models

arXiv:2607. 00397v1 Announce Type: cross Abstract: Understanding how complex cognitive functions are organized within artificial systems is central to interpreting large language models (LLMs) and relating them to biological cognition.

By Zhongxiang Sun, Haolang Lu, Qiang Ma, Qi Li, Qipeng Wang, Liang Pang, Chenyu Liu, Qiankun Li, Hao Sun, Kun Wang, Yi Zeng, Jun Xu, Guoqi Li, Ji-Rong Wen
arXiv AI
Oct 12

Neural networks are more modular than single neurons suggest

The paper argues that neural networks can exhibit modular organization even when individual neurons are not specialized. It introduces a nested hierarchy of modularity—unit-level, orthogonal, and linear—and shows that many vision, language, and RNN models lack unit-level modularity but still display clear functional modularity at the subspace level. The authors demonstrate that these subspaces can be causally validated through ablation and align with brain data, revealing distinct content/style or syntax/semantics separations.

By Shreya Saha, Benjamin Bergen, Meenakshi Khosla
arXiv AI
Jul 14

Lesioned Multimodal Language Models Reproduce Aphasic Picture-Naming Patterns

arXiv:2607. 11621v1 Announce Type: new Abstract: Aphasia following stroke commonly produces systematic naming errors with characteristic profiles, but whether general-purpose language models not designed for clinical simulation can reproduce these patterns remains untested.

By Yong Yang, Xiang Guan, Sophie Arheix-Parras, Saeed Ahmadi, Roger Newman-Norlund, Leonardo Bonilha, Christopher Rorden, Julius Fridriksson, Rutvik H. Desai, Srihari Nelakuditi
arXiv AI
Oct 16

Decomposing Brain-LLM Alignment with Interpretable Semantic Representations

The study investigates how a large language model (LLaMA2‑7B) aligns with human brain activity during naturalistic language comprehension by using SCRIBE, an interpretable semantic representation of 65 neurocognitively grounded properties. Variance partitioning on fMRI data from seven participants reveals that shared variance between LLaMA2‑7B and SCRIBE dominates across the brain, yet both representations also contribute unique variance. Further analysis shows that concrete semantic properties correlate more strongly with shared variance, while abstract properties do not show increased unique variance, and ablation experiments demonstrate that multiple semantic dimensions cumulatively influence both shared and unique brain-predictive variance.

By Camila Kolling, Mariya Toneva