RACR-MIL is a weakly‑supervised method for grading squamous cell carcinoma (SCC) from whole‑slide images, using an attention‑based multiple‑instance learning framework. It introduces a hybrid WSI graph to capture local tissue context and non‑local phenotypic dependencies, and applies rank‑ordering constraints on attention to prioritize higher‑grade tumor regions, mirroring pathologists’ diagnostic reasoning. The approach achieves state‑of‑the‑art performance, improving SCC grading accuracy by 3–9% over existing methods and up to 10% in tumor localization, and a pilot study showed pathologists reported increased grading efficiency in 60% of cases.
arXiv:2505.03380v2 Announce Type: replace Abstract: Accurate delineation of tumors and surrounding organs-at-risk is essential for radiotherapy, surgery and treatment response assessment, yet remains...
arXiv:2606. 27579v1 Announce Type: cross Abstract: Accurate assessment of tumor proportion score (TPS) in non-small cell lung cancer (NSCLC) is critical for treatment planning and prognosis.
arXiv:2609.00396v1 Announce Type: new Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
arXiv:2606. 00092v1 Announce Type: cross Abstract: Weakly-supervised classification of whole-slide images with attention-based multiple instance learning (ABMIL) on top of foundation features now reaches near-saturation on Camelyon16 slide-level performance, but the corresponding attention maps are an imperfect localization signal: in clinical interpretation, a model that classifies correctly without firing on the actual lesion is hard to trust.
The paper introduces a dual cross‑attention deep learning framework for automated grading of Cervical Intraepithelial Neoplasia (CIN) and prediction of Swede scores, using a newly released BUET Multi‑Center Colposcopy Dataset. The architecture fuses paired multimodal cervigrams and employs a custom composite loss to handle class imbalance, achieving 71.85% accuracy and 86.23% AUC‑ROC for three‑class CIN grading, and AUC‑ROC values between 75.7% and 88.4% for individual Swede score components. The total predicted Swede Score has a mean absolute error of 1.489, indicating potential for AI‑assisted colposcopy screening in resource‑limited settings.
The paper introduces a dual‑input, multi‑task learning framework that jointly segments and classifies bone tumors by applying bidirectional cross‑modal attention between a lesion crop and the full radiograph. Using a YOLO‑based detector and a dual‑stream DenseNet121 architecture, the model fuses fine‑grained lesion detail with global anatomical context through a novel cross‑modal attention fusion strategy and hierarchical multi‑scale feature fusion. On the multi‑institutional Bone Tumor X‑ray Radiograph Dataset, the approach outperforms single‑input baselines, achieving a Dice coefficient of 0.896 and a macro‑averaged F1‑score of 0.928, with an AUC of 0.999 for malignant osteosarcoma.
arXiv:2610.17603v1 Announce Type: cross Abstract: Background: Five-year survival prediction from hematoxylin-and-eosin whole-slide images could support risk stratification, but the task is weakly sup...
arXiv:2610.15669v2 Announce Type: replace-cross Abstract: Weak bag-level labels are widely available in computational pathology, whereas reliable instance-level annotations for whole-slide images rem...
arXiv:2502.02707v5 Announce Type: replace Abstract: Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervis...
The paper introduces Order-Aware Slab Multiple Instance Learning (OAS‑MIL) for predicting perineural invasion (PNI) in intrahepatic cholangiocarcinoma using preoperative T2‑weighted MRI. It treats each tumor‑centered MRI crop as an ordered sequence of overlapping 2.5D slabs, extracting slab‑level features with a shared encoder and aggregating them through both permutation‑invariant set‑attention and bidirectional sequence‑attention branches. In five‑fold patient‑level cross‑validation, OAS‑MIL achieved a mean AUROC of 0.770, outperforming volumetric and MIL baselines, indicating that axial order provides a useful inductive bias for weakly supervised PNI prediction.
The paper introduces Order‑Aware Slab Multiple Instance Learning (OAS‑MIL), a weakly supervised method that predicts perineural invasion (PNI) risk in intrahepatic cholangiocarcinoma using preoperative T2‑weighted MRI. Tumor‑centered MRI crops are split into ordered 2.5D slabs, and a shared encoder extracts features that are aggregated through both permutation‑invariant set‑attention and bidirectional sequence‑attention branches. In five‑fold patient‑level cross‑validation, OAS‑MIL achieved a mean AUROC of 0.770, outperforming volumetric and other MIL baselines, indicating that preserving axial order improves non‑invasive PNI prediction.
arXiv:2610.07694v1 Announce Type: new Abstract: The integrative analysis of histopathological Whole-Slide Images (WSIs) and transcriptomic profiles holds significant promise for cancer survival predi...