RACR-MIL is a weakly‑supervised method for grading squamous cell carcinoma (SCC) from whole‑slide images, using an attention‑based multiple‑instance learning framework. It introduces a hybrid WSI graph to capture local tissue context and non‑local phenotypic dependencies, and applies rank‑ordering constraints on attention to prioritize higher‑grade tumor regions, mirroring pathologists’ diagnostic reasoning. The approach achieves state‑of‑the‑art performance, improving SCC grading accuracy by 3–9% over existing methods and up to 10% in tumor localization, and a pilot study showed pathologists reported increased grading efficiency in 60% of cases.
By Anirudh Choudhary, Mosbah Aouad, Krishnakant Saboo, Angelina Hwang, Jacob Kechter, Blake Bordeaux, Puneet Bhullar, David DiCaudo, Steven Nelson, Nneka Comfere, Emma Johnson, Olayemi Sokumbi, Jason Sluzevich, Leah Swanson, Dennis Murphree, Aaron Mangold, Ravishankar Iyer
arXiv:2609.09189v1 Announce Type: cross
Abstract: High classification accuracy alone is insufficient for clinical image analysis, where calibrated confidence and reliable uncertainty estimates are es...
By Nisreen Albzour, Sarah S. Lam
OncoVision is a privileged‑information training framework that learns from mammography images and clinical data during training but performs inference using only mammographic images. It employs an attention‑based encoder‑decoder to jointly segment masses, calcifications, axillary findings, and breast tissue, and predicts ten structured clinical features such as BI‑RADS. Two late‑fusion strategies (Independent and Dependent) integrate imaging, radiomic, and clinical information to improve diagnostic precision, and a retrospective multi‑reader study showed higher diagnostic confidence, reduced reading time, and segmentation accuracy comparable to or better than radiologists.
By Istiak Ahmed, Galib Ahmed, K. Shahriar Sanjid, Md. Tanzim Hossain, Md. Nishan Khan, Md. Misbah Khan, Md. Arifur Rahman, Sheikh Anisul Haque, Sharmin Akhtar Rupa, Mohammed Mejbahuddin Mia, Mahmud Hasan Mostofa Kamal, Md. Mostafa Kamal Sarker, M. Monir Uddin
arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.
By Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, Minfeng Xu
The paper introduces the Cross‑Modal Triage Network (CMTN), a multimodal deep‑learning model that fuses a Swin Transformer V2 visual encoder with a PubMedBERT text encoder to perform severity‑based triage, pathology detection, and generate visual explanations for chest radiographs. Trained on 34,639 image‑text pairs from MIMIC‑CXR‑JPG, the CMTN achieves high ordinal agreement with reference labels (QWK = 0.9341) and excellent pathology detection (macro‑AUROC = 0.9970) while operating with 34 ms latency. However, a blinded clinical audit revealed low agreement with expert radiologists (QWK = 0.1399) and only modest spatial‑semantic concordance in heatmaps, underscoring the gap between algorithmic performance and clinical judgment.
By Zinah Ghulam, Richa Mittal, Eranga Ukwatta
The paper introduces FFM-CP, a framework that fuses multiple pathology vision‑language foundation models for few‑shot learning. It aligns heterogeneous representations with an Orthogonal Procrustes transformation, then uses a unified graph to refine support‑image features and class prototypes across backbones. Experiments on six histopathology datasets show that FFM‑CP outperforms the best single adapted model in 50 of 54 few‑shot comparisons.
By Anh-Tien Nguyen, Trung DQ. Dang, Nghiem Tuong Diep, Bui Ngoc Han Nguyen, Tan-Ha Mai, Miriam Cindy Maurer, Phuong Hoa Nguyen, Thi Thuy Uyen Nguyen, Youngjun Park, Daniel Sonntag, Duy Minh Ho Nguyen, Anne-Christin Hauschild
arXiv:2610.08528v1 Announce Type: cross
Abstract: Clinical diagnosis is inherently a structured reasoning process, yet existing deep learning models often bypass this structure by mapping image featu...
By Asim Khan, Samee Ullah Khan, Dwarikanath Mahapatra
arXiv:2609.15225v1 Announce Type: new
Abstract: Objective: To develop an intelligent framework, termed CUA-Net, for the automated classification of congenital uterine anomalies (CUA) without requirin...
By Yueyue Xu, Yuhao Huang, Jiaxiao Deng, Yuanji Zhang, Haoming Zhang, Jiajia Qu, Shiying Zheng, Xiaomei Tang, Haining Chen, Chengcai Chen, Yiyi Wu, Xin Yang, Dong Ni
arXiv:2610.34529v1 Announce Type: cross
Abstract: Background/Objectives: Rapid differentiation of ischemic and hemorrhagic stroke subtypes is vital for acute management. Although current deep learnin...
By Tansel Uyar
arXiv:2610.17603v1 Announce Type: cross
Abstract: Background: Five-year survival prediction from hematoxylin-and-eosin whole-slide images could support risk stratification, but the task is weakly sup...
By Hikmat Khan, Metin N. Gurcan, Anil Parwani, Wendy L. Frankel, Wei Chen, Muhammad Khalid Khan Niazi
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
MIST is a multimodal survival prediction framework that fuses whole-slide images and genomic profiles by representing genomic features as tokens that query histology context tokens derived from a foundation model. The architecture enriches molecular information with histology context before survival prediction, avoiding late-stage merging of separately encoded modalities. Training incorporates discrete-time survival prediction, genomic feature masking, WSI dropout, and contrastive alignment, and demonstrates improved external C-index across colon, renal, lung, and glioblastoma cohorts compared to standard fusion baselines.
By Muhammet Sami Yavuz, Sabri Mustafa Kahya, Richard R. Chen, Jana Lipkova, Benedikt Wiestler