arXiv:2608. 05095v1 Announce Type: new Abstract: Agents for long term reasoning require a memory that can be efficiently and effectively updated over time, as new facts and external feedback continue to arrive.
By Xiawei Yue, Boran Wang, Xiaoqing Zhang, Shuxin Zheng, Ziwei Zhang
Agents for long term reasoning require a memory that can be efficiently and effectively updated over time, as new facts and external feedback continue to arrive. Recently, graph memory has been adopted to offer structural organization for multi-hop retrieval and reasoning.
arXiv:2610.11920v1 Announce Type: new
Abstract: For persistent and personalized conversational agents, memory systems can enable them to remember, update, and reason over long histories by storing pa...
By Yichen Liu, Chunfeng Yuan, Haowei Liu, Wenjuan Li, Zefeng Lin, Bing Li, Xu Chen, Weiming Hu
arXiv:2608.21810v1 Announce Type: cross
Abstract: Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal...
By Md Asaduzzaman Jabin, Khoa Le, Lin Zhao, Tianming Liu
ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.
By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini
PIA is a personal intelligence agent that works alongside a consumer health agent to convert health conversations into structured clinical records and to transform those records into a synthesized understanding of the user. It uses a memory system with four controls—extraction, memory, retrieval, and understanding—each supported by a health module that includes a schema, medical alias dictionary, knowledge graph, and temporal rules. The agent demonstrates that deeper memory injection—from simple recall to a health snapshot to a causal trajectory—yields progressively richer answers, while also revealing challenges such as missing self‑reported data, the influence of question phrasing, and the presence of structural noise in causal links.
By Jeonghun Yoon, Dongchan Kim, Hongyeon Yu, Young-Bum Kim, Jaegul Choo
arXiv:2603. 03292v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields.
By Wenhao Wu, Zhentao Tang, Yafu Li, Shixiong Kai, Mingxuan Yuan, Zhenhong Sun, Chunlin Chen, Zhi Wang
arXiv:2609.22239v1 Announce Type: new
Abstract: Ambient AI is increasingly adopted in healthcare to automatically generate clinical notes from patient-clinician conversations, with the potential to s...
By Jakir Hossain, Yi-Fei Zhao, Hongjian Wang, Minmei Shih, Katie Leigh Mullen, Ahmad P. Tafti, Leming Zhou, Manoj Purohit, William Hogan, Jay Zeng, Elizabeth Skidmore, Yanshan Wang
The paper introduces STAM, a state‑transition‑aware memory framework for large language model agents that process clinical records. STAM records changes in a patient’s state as new entries arrive, using semantic retrieval and typed clinical relations to separate current information (Active) from superseded or resolved information (History). During retrieval, a query‑dependent gate selects the appropriate historical memory, enabling accurate question answering and state‑maintenance diagnostics across four longitudinal clinical benchmarks.
By Maryam Haghifam, Zahra Rajabi, Yizhou Sun, Carlos Morato
arXiv:2604. 06684v2 Announce Type: replace Abstract: Clinical reasoning over electronic health records (EHRs) is a fundamental yet challenging task in modern healthcare.
By Yue Fang, Weibin Liao, Yuxin Guo, Jiaran Gao, Hongxin Ding, Jinyang Zhang, Xinke Jiang, Zhibang Yang, Junfeng Zhao, Yasha Wang, Liantao Ma
REFINE is a framework that refines medical concept representations by creating patient‑specific temporal graphs from a global text‑attributed knowledge graph. It uses a reinforcement learning policy to allocate a personalized graph expansion budget for each observed code, then processes the resulting graph with a heterogeneous GNN and a frozen LLM that refines representations via graph‑aware soft prompts. Experiments on MIMIC‑III and MIMIC‑IV demonstrate that REFINE consistently improves various EHR prediction backbones, surpasses strong baselines, and shows robust gains across ablation studies, KG selection, and data insufficiency scenarios.
By Mohsen Nayebi Kerdabadi, Arya Hadizadeh Moghaddam, Dongjie Wang, Zijun Yao
arXiv:2608.29528v1 Announce Type: new
Abstract: Longitudinal clinical agents must maintain an evolving patient state from evidence distributed across visits, time points, and specialties. However, ho...
By Hei Ting (Una), Chan, Chenwei Wu, Xueshen Liu, Boyuan Zheng, Liyue Shen, Jiasi Chen, Z. Morley Mao