arXiv:2510.03536v3 Announce Type: replace-cross
Abstract: Multi-turn medical question answering (QA) aims to model realistic clinical diagnosis, where a doctor gathers patient information across mult...
By Zhaohan Meng, Zaiqiao Meng, Siwei Liu, Hao Xu, Ke Yuan, Iadh Ounis
arXiv:2608.29528v1 Announce Type: new
Abstract: Longitudinal clinical agents must maintain an evolving patient state from evidence distributed across visits, time points, and specialties. However, ho...
By Hei Ting (Una), Chan, Chenwei Wu, Xueshen Liu, Boyuan Zheng, Liyue Shen, Jiasi Chen, Z. Morley Mao
arXiv:2607. 22566v1 Announce Type: new Abstract: MedLoCoMo is a Medical Long-Context Memory benchmark for patient-specific clinical reasoning over multi-admission medical dialogue.
By Zeyu Zhang, Ziqing Wang, Kaize Ding
arXiv:2607. 12893v1 Announce Type: new Abstract: Long-term memory has become a foundational capability for LLM-based agents that accompany users across extended, multi-session interactions.
By Xixuan Hao, Zeyu Zhang, Zehao Lin, Yihang Sun, Ziliang Guo, Xichong Zhang, Yuxuan Liang, Feiyu Xiong, Zhiyu Li
arXiv:2608.21810v1 Announce Type: cross
Abstract: Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal...
By Md Asaduzzaman Jabin, Khoa Le, Lin Zhao, Tianming Liu
PIA is a personal intelligence agent that works alongside a consumer health agent to convert health conversations into structured clinical records and to transform those records into a synthesized understanding of the user. It uses a memory system with four controls—extraction, memory, retrieval, and understanding—each supported by a health module that includes a schema, medical alias dictionary, knowledge graph, and temporal rules. The agent demonstrates that deeper memory injection—from simple recall to a health snapshot to a causal trajectory—yields progressively richer answers, while also revealing challenges such as missing self‑reported data, the influence of question phrasing, and the presence of structural noise in causal links.
By Jeonghun Yoon, Dongchan Kim, Hongyeon Yu, Young-Bum Kim, Jaegul Choo
The paper introduces BRIE, a scalable framework that automatically creates question–answer pairs from longitudinal electronic health record notes, validated by nineteen clinicians. It offers a continuously maintainable benchmark for evaluating large language models in clinical settings, addressing limitations of manual, costly, and quickly outdated existing benchmarks. Experiments across nine LLMs and five inference strategies reveal that even state‑of‑the‑art systems often miss clinically important information, especially for synthesis‑heavy queries.
The paper introduces BRIE, a continuously maintainable benchmark for evaluating large language models (LLMs) in electronic health record (EHR) information retrieval. It presents a scalable framework that automatically generates question–answer pairs from longitudinal EHR notes, validated by nineteen clinicians. The benchmark allows assessment of multiple inference strategies and highlights that state‑of‑the‑art LLMs often miss clinically important information, especially when synthesis across documents is required.
By Jordan L. Cahoon, Chloe O. Stanwyck, Sulaiman Somani, Philip Chung, Kevin R Keet, Kameron C. Black, Andrea T. Fisher, Sarita Khemani, Jerry Liu, Stephen Ma, Saloni K. Maharaj, Rita M. Pandya, Eduardo Perez-Guerrero, Priyanka Pillai, Lisa Shieh, David J. H. Wu, James Xie, James C. McAvoy, Teresa Nguyen, Jessica Tran, Lucy Yin, Bridget Lin, Alison Callahan, Jason A. Fries, Nigam H. Shah, Emily Alsentzer
arXiv:2609.37587v1 Announce Type: cross
Abstract: Longitudinal electronic health record (EHR) modeling requires integrating new visits with an expanding patient history. Yet the continual accumulatio...
By Zijie Meng, Xiwei Dai, Yingying Zhang, Jian Wu, Xian Wu, Zuozhu Liu
arXiv:2608. 03463v1 Announce Type: new Abstract: Long-term memory is essential for LLM-based agents to sustain interactions and reliably leverage distant history.
By Yuxin Liao, Le Wu, Min Hou, Hao Liu, Han Wu, Zishu Wang
arXiv:2610.00562v1 Announce Type: cross
Abstract: Longitudinal clinical reasoning requires large language models (LLMs) to identify and integrate relevant evidence distributed across extended patient...
By Taye Akinrele, Noorbakhsh Amiri Golilarz, Subash Neupane, Sudip Mittal, Shahram Rahimi
arXiv:2607. 09322v1 Announce Type: new Abstract: In this work, we introduce LongMedBench, a real-world EHR-based benchmark for long-horizon clinical decision-making.
By Yanzhen Chen, Zihan Xu, Xiaocheng Zhang, Zhiting Fan, Weiqi Zhai, Hongxia Xu, Zuozhu Liu