InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
The paper introduces FreNet, a feature reconfiguration framework that incorporates visual priors for medical lesion segmentation. FreNet performs pixel‑level reconfiguration before encoding using an Implicit Prior Neural Network (IPNN) that leverages SAM, and feature‑level reconfiguration during encoding via a Dual‑domain Feature Reconfiguration (DFR) module, which includes a Frequency Decoupling Module (FDM) and a Spatial Localization Module (SLM). Experiments on nine benchmarks across three imaging modalities show that FreNet outperforms state‑of‑the‑art methods, achieving a 5.0% Dice improvement over the best baseline on the ETIS dataset and a 7.2% improvement over SAM.
By Yinan Liu, Jiankang Hong, Zhen Gao, Ye Lu
Feature Reconfiguration With Visual Prior for Medical Lesion Segmentation proposes FreNet, a framework that reconfigures images and features before and during encoding to improve lesion segmentation. It introduces an Implicit Prior Neural Network that uses a visual prior from SAM to suppress background responses, and a Dual-domain Feature Reconfiguration module that decouples features in frequency and spatial domains to better handle diverse lesion morphology. Experiments on nine benchmarks across three imaging modalities show FreNet outperforms state‑of‑the‑art methods, achieving a 5.0% Dice improvement over the best prior method on the ETIS dataset.
arXiv:1812.00877v2 Announce Type: replace-cross
Abstract: Segmentation of skin lesion boundaries in dermoscopic imaging is an important prerequisite step for computer-aided diagnosis of malignant mel...
By Glib Kechyn
arXiv:2606. 26712v1 Announce Type: cross Abstract: Skin lesion segmentation is a key task in computer-aided dermatological diagnosis, where accuracy directly impacts downstream analysis and disease classification.
By Jingjun Gu, Chaojie Shen, Yifeng Cao, Wei Zhang, Yiliu Li, Aobo Fan
arXiv:2608. 15537v1 Announce Type: cross Abstract: Accurate boundary delineation remains a persistent challenge in dermoscopic image segmentation because of blurred lesion margins, heterogeneous textures, and complex background artifacts.
By Wang Jiangtao, Nur Intan Raihana Ruhaiyem, Fu Panpan, Yang Yu, Huang Yan
arXiv:2509.22404v2 Announce Type: replace
Abstract: Anatomical understanding, which is the ability to identify, localize, or segment anatomical structures, is critical in medical image analysis; howe...
By Yiwei Li, Yikang Liu, Jiaqi Guo, Lin Zhao, Zheyuan Zhang, Xiao Chen, Boris Mailhe, Ankush Mukherjee, Terrence Chen, Shanhui Sun
arXiv:2603. 12514v2 Announce Type: replace-cross Abstract: Accurate detection and localization of traumatic injuries in abdominal CT remain challenging because voxel-level annotations are limited and expensive to obtain.
By Shivam Chaudhary, Sheethal Bhat, Andreas Maier
arXiv:2608.22619v1 Announce Type: cross
Abstract: Generative segmentation provides an alternative to direct pixel-wise prediction by operating on learned latent representations, but effective image-t...
By Md Maklachur Rahman, Md Hasan Al Banna, Saraf Anjum, Mahmudul Hasan, Tracy Hammond
arXiv:2512. 21414v2 Announce Type: replace-cross Abstract: Recent tool-use frameworks powered by vision-language models (VLMs) improve image understanding by grounding model predictions with specialized tools.
By Christina Liu, Alan Q. Wang, Joy Hsu, Jiajun Wu, Ehsan Adeli
arXiv:2607. 24453v1 Announce Type: cross Abstract: Learning from minimal human supervision is a long-standing goal in medical image analysis, where dense expert annotations are costly.
By Mingzhi Xu, Yizhe Zhang
arXiv:2606. 19824v1 Announce Type: cross Abstract: Accurate segmentation of thin, tortuous anatomical structures, such as retinal vessels, cerebral vasculature, and facial wrinkles, remains challenging due to low contrast, frequent discontinuities, and severe class imbalance.
By Junho Moon, Haejun Chung, Ikbeom Jang