ConPro introduces a self‑supervised pretraining method for vessel segmentation in digital subtraction angiography (DSA) by using a contrast projection target— the normalized drop of each pixel below its temporal median. On the DIAS and DSCA datasets, ConPro outperforms training from scratch across 10%, 20%, and 50% labeled data, and it is the best among compared methods on DSCA at 20% and 50% labels. When combined with semi‑supervised training, ConPro‑derived weights boost the UniMatch baseline by 0.5–2.0 Dice points and 0.9–2.3 clDice points, achieving 75.4 Dice on DIAS and 81.3 on DSCA.
By Xinge Guo, Yuanhao Wang, Liqi Shu, Yang Liu, Min Xu
The paper proposes a two‑stage learning framework for multi‑organ segmentation that handles partially annotated datasets and domain shifts. First, the model learns accurate segmentations from available annotations to build robust feature representations. Second, it introduces learnable organ prototypes and a Sinkhorn‑triplet loss to enforce organ‑wise feature consistency across datasets, keeping embeddings of the same organ close while separating different organs, even when annotations are missing.
By Dakini Mallam Garba, Salim Abdou Daoura
The paper introduces SSS, a semi‑supervised framework that builds on the Vision Foundation Model SAM‑2 to improve medical image segmentation. It combines a weak‑to‑strong consistency regularization with a Discriminative Feature Enhancement mechanism and a prompt generator that uses Physical Constraints with a Sliding Window to supply prompts for unlabeled data. Experiments on the ACDC and BHSD datasets show that SSS outperforms prior methods, achieving a 53.15 Dice score on BHSD, a +3.65 improvement over the state of the art.
By Hongjie Zhu, Xiwei Liu, Rundong Xue, Zeyu Zhang, Yong Xu, Daji Ergu, Ying Cai, Yang Zhao
DART is a new RGB‑D pretraining method for surgical vision foundation models that incorporates pseudo‑labeled depth maps as a pixel‑space reconstruction target during training. By adding a depth reconstruction head to DINOv2’s masked iBOT framework, DART improves representation quality without affecting downstream RGB‑only fine‑tuning or inference. Across eight surgical benchmarks—including segmentation, depth estimation, and image‑level recognition—DART outperforms both natural‑image and in‑domain baselines, demonstrating that geometric pseudo‑labels can strengthen foundation model pretraining without extra labels or inference cost.
By John J. Han, Adam Schmidt, Muhammad Abdullah Jamal, Jie Ying Wu, Omid Mohareri
The paper presents a two‑pipeline framework for retinal fundus analysis that combines four‑class disease classification with vessel segmentation. It fine‑tunes eight ImageNet‑pretrained CNNs on the FIVES dataset, applies five gradient‑based explanation methods to assess model interpretability, and benchmarks ten U‑Net variants—including transformer‑based and attention‑enhanced architectures—on the FIVES and DRIVE datasets. The best classification results come from ResNet101 (94.17% accuracy), while the strongest segmentation performance is achieved by Attention U‑Net with a ResNet101V2 backbone, improving DRIVE IoU from 60.80% to 64.83%.
By Fatema Tuj Johora Faria, Mukaffi Bin Moin, Pronay Debnath, Asif Iftekher Fahim, Faisal Muhammad Shah
ReG-SAM is a SAM-based framework designed for 2D vessel segmentation in medical images. It introduces reference graph prompt embeddings (GPEs) and vascular prototype embeddings (VPEs) to capture global spatial and fine-grained modality-specific vessel features, respectively. By building a modality-wise vascular database and learning these embeddings from reference masks, ReG-SAM consistently outperforms existing baselines across 19 datasets, especially on thin vessels.
By Donghang Lyu, Zichen Zhang, Oleh Dzyubachyk, Marius Staring
arXiv:2603. 18846v3 Announce Type: replace-cross Abstract: Foundation models are used to extract transferable representations from large amounts of unlabeled data, typically via self-supervised learning (SSL).
By Samuel Ofosu Mensah, Camila Roa, Kerol Djoumessi, Philipp Berens
GazeRefine is a training‑free framework that uses eye‑gaze data as an inference‑time prompt for zero‑shot medical image segmentation. It converts sparse, duration‑weighted fixations into foreground and background priors that initialize semantic prototypes in a frozen DINOv3 feature space, then iteratively refines these prototypes through discrimination, affinity propagation, and anchoring to the gaze guidance. The method achieves strong results on colonoscopy polyp segmentation and competitive performance on prostate MRI, demonstrating that gaze‑guided prototype refinement can enable segmentation without dense expert annotations or model fine‑tuning.
By Mohammed Oussama Benyahia, Marouane Tliba, Mohamed Amine Kerkouri, Taifour Yousra, Bin Wang, Max Bengtsson, Gorkem Durak, Elif Keles, Zuheng Ming, Marek Penhaker, Azeddine Beghdadi, Ulas Bagci, Aladine Chetouani
arXiv:2606. 05107v1 Announce Type: cross Abstract: We propose a label-free approach to adapt powerful but generic vision foundation models to specialized scientific domains.
By Elouan Gard\`es, Seung Eun Yi, Kartik Ahuja, Th\'eo Moutakanni, Huy V. Vo, Piotr Bojanowski, Wolfgang M. Pernice, Lo\"ic Landrieu, Camille Couprie
The paper introduces Spatial‑FAD, a few‑shot medical anomaly detection framework that fuses Vision‑Language Model (CLIP) semantics with spatial priors from Vision Foundation Models (DINO). A VFM‑enhanced adapter injects structural affinity into CLIP features, while a sliding‑window aggregation produces high‑resolution embeddings for finer lesion localization. Prototype‑enhanced support memory further improves efficiency and performance, yielding significant gains on Liver CT, Retinal OCT, and Brain MRI datasets, notably an 11.4% Dice improvement in 4‑shot scenarios.
By Juzheng Miao, Yuchen Yuan, Cheng Chen, Pheng-Ann Heng
arXiv:2509.22404v2 Announce Type: replace
Abstract: Anatomical understanding, which is the ability to identify, localize, or segment anatomical structures, is critical in medical image analysis; howe...
By Yiwei Li, Yikang Liu, Jiaqi Guo, Lin Zhao, Zheyuan Zhang, Xiao Chen, Boris Mailhe, Ankush Mukherjee, Terrence Chen, Shanhui Sun
arXiv:2607.10851v2 Announce Type: replace
Abstract: Medical image classification models are ideally expected to identify diagnostically relevant regions while making predictions, yet standard classif...
By Tonmoy Hossain, Atiqur Rahman, Farhana Hossain Swarnali, Miaomiao Zhang