arXiv AI

HDDPM: Heteroscedastic Denoising Diffusion Probabilistic Model for Quantitative Low-Count Brain PET Recovery

arXiv:2606. 28513v1 Announce Type: cross Abstract: Positron emission tomography (PET) seeks to balance diagnostic quality with ra-diation dose.

arXiv Computer Vision
Sep 16

Efficient 3D Whole-Body PET Image Denoising via Conditional Rectified Flow With Optimized Sampling Strategy

The paper introduces a one‑pass conditional 3D rectified flow (3D Flow) framework for denoising whole‑body PET images, employing an optimized non‑uniform sampling strategy and a linear‑interpolant velocity‑matching objective. It reconstructs a full 3D volume in about 30 seconds, dramatically faster than multi‑hour 3D diffusion models, while maintaining high global image quality and lesion conspicuity even at ultra‑low doses (down to 1/100 of standard). Zero‑shot transfer tests on independent clinical data demonstrate robust performance across datasets and unseen dose levels.

By Jiale Shen, Guolin Wang, Chenhao Wang, Xinhui Su, Wei Luo, Feng Yu
arXiv Machine Learning
Jul 15

GenDiff: A Dose and Anatomy Aware Diffusion Model with Structural Prior Refinement for Low-Dose CT Reconstruction and Generalization

arXiv:2607. 11941v1 Announce Type: cross Abstract: Computed tomography (CT) is a critical imaging modality for clinical diagnosis, but reducing radiation dose inevitably introduces severe noise and structured artifacts that degrade image quality.

By Md Imam Ahasan, Guangchao Yang, A F M Abdun Noor, Kah Ong Michael Goh, S. M. Hasan Mahmud, Md Mahfuzur Rahman
arXiv AI
Aug 6

Delta-Diffusion: Modeling Longitudinal Brain Amyloid-PET Trajectories via Conditional Poisson Diffusion Bridge

arXiv:2606. 22216v2 Announce Type: replace-cross Abstract: While longitudinal brain PET imaging is the gold standard for quantifying the spatiotemporal accumulation of Beta-amyloid, its widespread clinical utility is constrained by high operational costs and cumulative radiation risks.

By Yongheng Sun, Minhui Yu, Mengqi Wu, Maureen Kohi, Mingxia Liu
arXiv AI
Aug 3

Dense Temporal Contrast Synthesis via Conditioned Latent Transport

arXiv:2607. 29394v1 Announce Type: cross Abstract: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer management, but reliance on gadolinium-based contrast agents (GBCAs) restricts use in contraindicated populations, prolongs scan protocols, and presents environmental toxicity concerns.

By Smriti Joshi, Apostolia Tsirikoglou, Daniel M. Lang, Richard Osuala, Noah M\'arquez Varaa, Alejandro Guzman, Grzegorz Skorupko, Sebastian Ibarra Arregui, Lidia Garrucho, Akane Ohashi, Dimitra Ntoula, Eugen Divjak, O\u{g}uz Lafc{\i}, Jan C. Peeken, Julia A. Schnabel, Fredrik Strand, Oliver Diaz, Karim Lekadir
arXiv Computer Vision
Sep 3

Physics-Driven Independent Pair Generation for Iterative Self-Supervised Low-Dose CT Denoising

The paper introduces a physics‑driven, cross‑domain iterative framework for self‑supervised low‑dose CT denoising. It first uses a learned sinogram prior and the LDCT noise model to separate Poisson and Gaussian noise components, then applies binomial and Gaussian data thinning to create two training pairs with independent noise realizations. These pairs train an image‑domain network whose outputs are forward‑projected to refine the prior, yielding consistent performance gains over existing self‑supervised baselines and comparable results to supervised methods.

By Xianlei Han, Shaoyu Wang, Jiancheng Fang, Weiwen Wu, Qiegen Liu
arXiv AI
Aug 11

Toward CT-Equivalent Image Quality in Low-Dose Radiotherapy Planning: Conditional Diffusion-Based CBCT-to-CT Synthesis and the Impact of CBCT Input Representation

arXiv:2608. 08919v1 Announce Type: cross Abstract: During standard radiotherapy planning, repeated CT acquisitions are often required for patient registration, verification, and adaptive planning, resulting in increased cumulative X-ray dose.

By Alzahra Altalib, Chunhui Li, Christopher Hamill Taylor, Sankar Pillai, Alessandro Perelli