The paper introduces Colorist, a data‑augmentation method that uses classical statistical color matching to generate domain‑shifted medical images. By applying global mean‑standard‑deviation matching in RGB space, Colorist creates structurally intact variations without neural networks, outperforming deep generative models in fidelity and color alignment. Across multiple medical imaging datasets, it boosts balanced accuracy by up to 9% over state‑of‑the‑art domain‑generalization regularizers and 13% over no augmentation, while reducing computational cost and preserving anatomical structure.
By Sebastian Doerrich, Francesco Di Salvo, Shyam Nandan Rai, Marco Lents, Christian Ledig
arXiv:2607. 03253v1 Announce Type: cross Abstract: As hematoxylin & eosin (H&E) staining constitutes the primary entry point in routine diagnostic workflows, computer-aided diagnosis from whole-slide H&E images is of particular clinical relevance.
By Ivica Kopriva, Dario Sitnik, Arijana Pacic, Karolina Krstanac, Irena Veliki Dalic, Marijana Popovic Hadzija
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
arXiv:2407. 13632v2 Announce Type: replace-cross Abstract: Deploying deep learning-based imaging tools across various clinical sites poses significant challenges due to inherent domain shifts and regulatory hurdles associated with site-specific fine-tuning.
By Abhijeet Parida, Antonia Alomar, Zhifan Jiang, Pooneh Roshanitabrizi, Austin Tapp, Maria Ledesma-Carbayo, Ziyue Xu, Syed Muhammed Anwar, Marius George Linguraru, Holger R. Roth
arXiv:2609.00984v1 Announce Type: cross
Abstract: Virtual staining aims to computationally generate target-stained histopathological images while reducing the cost and time associated with convention...
By Baoshun Wang, Weiping Lin, Linwu Wang, Yihuang Hu, Baptiste Magnier, Liansheng Wang
arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.
By Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, Minfeng Xu