ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.
By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini
arXiv:2606. 29746v1 Announce Type: new Abstract: Navigating the deluge of heterogeneous medical data, from academic literature (PubMed) to clinical guidelines (Web) and private knowledge bases, remains a critical bottleneck for evidence-based medicine.
By Maolin Liu, Fanyu Xu, Ruoqing Xu, Jiahang Zhang, Hao Wang, Rui Wang
Navigating the deluge of heterogeneous medical data, from academic literature (PubMed) to clinical guidelines (Web) and private knowledge bases, remains a critical bottleneck for evidence-based medicine. While commercial black-box tools lack transparency, standard open-source RAG implementations frequently suffer from reasoning drift when handling complex, long-tail queries.
arXiv:2607. 06452v1 Announce Type: cross Abstract: Biomedical question answering requires not only accurate extraction of information from scientific literature but also reliable integration of evidence across multiple documents.
By Taeyun Roh, Eunha Lee, Wonjune Jang, Sohyun Chung, Junha Jung, Jaewoo Kang
arXiv:2601. 04524v2 Announce Type: replace Abstract: Understanding biomedical experiments provides a foundation for downstream tasks, e.
By Haofei Hou, Shunyi Zhao, Fanxu Meng, Kairui Yang, Lecheng Ruan, Qining Wang
arXiv:2607. 20926v1 Announce Type: new Abstract: Scientific research involves complex information-seeking and reasoning workflows across heterogeneous sources.
By Yinhao Tang, Youqing Fang, Yanan Sun, Wenran Liu, Weiming Zhang, Bin Liu, Kuikun Liu, Wenwei Zhang, Kai Chen