arXiv:2606. 29746v1 Announce Type: new Abstract: Navigating the deluge of heterogeneous medical data, from academic literature (PubMed) to clinical guidelines (Web) and private knowledge bases, remains a critical bottleneck for evidence-based medicine.
By Maolin Liu, Fanyu Xu, Ruoqing Xu, Jiahang Zhang, Hao Wang, Rui Wang
arXiv:2606. 08093v1 Announce Type: new Abstract: Pathology is the cornerstone of modern medicine, where accurate decision-making relies heavily on evidence-based practices.
By Zhe Xu, Zhengyu Zhang, Zhiyuan Cai, Jiahao Xu, Yijie Lin, Ziyi Liu, Junlin Hou, Hongyi Wang, Yuxiang Nie, Ling Liang, Yihui Wang, Yingxue Xu, Ronald Cheong Kin Chan, Li Liang, Hao Chen
PathPocket is a multimodal AI co‑pilot that grounds pathology decision‑making in evidence. It builds the largest pathology evidence corpus (≈110,472 documents) and a hypergraph of 4.55 million entities and 7.10 million relations to support traceable reasoning. The system handles text and multimodal queries, including ROI and gigapixel whole‑slide images, and outperforms current state‑of‑the‑art models on a benchmark of over 200,000 real‑world cases, improving pathologists’ diagnostic accuracy and confidence.
By Zhe Xu, Zhengyu Zhang, Zhiyuan Cai, Jiahao Xu, Yijie Lin, Ziyi Liu, Junlin Hou, Hongyi Wang, Yuxiang Nie, Yihui Wang, Jiabo Ma, Ling Liang, Yingxue Xu, Zhengrui Guo, Guanghao Wu, Danyi Li, Ziqi Zhou, Donglin Tan, Zhijian Cen, Ying Tan, Xiaolin Liu, Qi Xie, Xiaoying Tang, Xi Peng, Cheng Deng, Lijuan Qu, Ronald Cheong Kin Chan, Li Liang, Hao Chen
ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.
By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini
arXiv:2608. 11420v1 Announce Type: new Abstract: Medical diagnostic reasoning is a high-impact use case for LLMs that carries significant implications for the health and wellbeing of users.
By Del Coburn, Scott Sanner, Dan Silver
arXiv:2607. 24850v2 Announce Type: replace-cross Abstract: Recent advances in large language models (LLMs) have enabled search agents to autonomously tackle complex tasks across extended search and reasoning horizons.
By Lang Mei, Xiaohan Yu, Chong Chen, Liyan Liu, Xiangnan Chen, Jinchao Ma, Chao Feng, Li Huang, Siyu Mo, Sichen Kang, Yunkun Xu, Zhihan Yang, Zhujun Xue, Jingren Zhang, Qing He, Yingdi Huang, Hao Jiang, Ziao Ma, Zewei Pan, Minhao Sun, Zhuo Tao, Jinzhao Xiao, Gangtao Xin, Huanyao Zhang, Wenjian Zhang, Jiangshan Zhang, Guojie Zhu, Fangzhou Zou, Jiaxin Mao, Wentao Zhang
The paper introduces Biomedica, an open-source dataset sourced from PubMed Central that includes over 6 million scientific articles and 24 million image‑text pairs, along with 27 metadata fields and expert human annotations. To facilitate use, the authors provide scalable streaming and search APIs via a web server. They demonstrate the dataset’s value by training embedding models, chat‑style models, and retrieval‑augmented chat agents, all of which outperform previous open systems in their categories.
By Alejandro Lozano, Min Woo Sun, James Burgess, Jeffrey J. Nirschl, Christopher Polzak, Yuhui Zhang, Liangyu Chen, Jeffrey Gu, Ivan Lopez, Josiah Aklilu, Anita Rau, Austin Wolfgang Katzer, Collin Chiu, Orr Zohar, Xiaohan Wang, Alfred Seunghoon Song, Chiang Chia-Chun, Robert Tibshirani, Serena Yeung-Levy
DataSTORM is an LLM‑based agentic system designed to conduct deep research over large‑scale structured databases and internet sources. It applies principles of Exploratory Data Analysis and Data Storytelling to frame research as a thesis‑driven analytical process, iteratively generating hypotheses, performing quantitative reasoning, and crafting coherent narratives. Evaluations on InsightBench and a new ACLED‑based dataset show that DataSTORM surpasses existing systems, achieving significant improvements in insight‑level recall and summary‑level scores.
By Shicheng Liu, Yucheng Jiang, Sajid Farook, Camila Nicollier Sanchez, David Fernando Castro Pena, Monica S. Lam
arXiv:2606. 05241v1 Announce Type: cross Abstract: Public benchmarks enable fair and reproducible evaluation of LLM reasoning, but they become fragile for deep research agents that actively search the web during inference.
By Yongjie Wang, Xinyue Zhang, Kunhong Yao, Zhiwei Zeng, Kaisong Song, Jun Lin, Zhiqi Shen
arXiv:2607. 15280v1 Announce Type: new Abstract: Sequential diagnosis requires balancing diagnostic accuracy against resource costs through iterative information gathering.
By Shaoting Tan, Ning Liu, Yuntao Du, Shuyue Wei, Wu Shuai, Qian Li, Yanyu Xu, Wei Zhang, Lizhen Cui, Haitao Yuan
arXiv:2609.27297v2 Announce Type: replace
Abstract: Agentic science envisions many autonomous agents investigating concurrently while building on a shared, evolving body of scientific knowledge. This...
By Yuan Huang, Sihan Hu, Hongyu Gu, Chao Ma, Jiaxing Zhang, Zhiyong Zou, Caiyu Fan, Yan Xiao, Mingjun Xu, Chenyu Xie, Mingzhen Ju, Zhehao Ma, Qi Zhang, Baozong Wang, Yu Li, Zhiyuan Yao, Ruoxue Liao, Xinyu Li, Linfeng Zhang, Kun Chen, Weinan E
arXiv:2605. 06177v2 Announce Type: replace Abstract: Reproducing and comparing deep research agents today is hard: the same backbone evaluated on the same benchmark can report different accuracies across papers because the harness and tool registry differ, and integrating a new model into a comparable evaluation surface costs weeks of model-specific engineering.
By Jinge Wu, Hongjian Zhou, Mingde Zeng, Jiayuan Zhu, Junde Wu, Jiazhen Pan, Ayush Noori, Sean Wu, Honghan Wu, Fenglin Liu, David A. Clifton