Observer Choice and Threshold Selection in Retinal Vessel Segmentation: A Subject-Separated Evaluation

The study investigates how the choice of annotation used to set a segmentation threshold influences retinal vessel segmentation performance. Using all 28 CHASE DB1 images and two human observers, the authors fit random forests and Extra Trees models, then compare five threshold policies—including fixed, observer‑tuned, mean‑observer, and maximin tuning—on the same score maps. Results show that maximin tuning alters thresholds in most fits but yields negligible changes in worst‑observer Dice scores, suggesting no accuracy advantage in this cohort.

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• computer-vision