arXiv:2607. 03009v1 Announce Type: new Abstract: Background: Foundation models (FMs) trained on large-scale unlabeled physiological data have emerged as a promising paradigm for medical artificial intelligence.
By Beatrice Zanchi, Giuliana Monachino, Alvise Dei Rossi, Luigi Fiorillo, Georgia Sarquella-Brugada, Giulio Conte, Francesca Dalia Faraci
arXiv:2606. 02605v1 Announce Type: cross Abstract: Coronary artery stenosis is a common cardiovascular disease, with severe, untreated cases posing significant risks of heart attack.
By Nikola Cenikj, \"Ozg\"un Turgut, Alexander M\"uller, Alexander Steger, Jan Kehrer, Marcus Brugger, Daniel Rueckert, Philip M\"uller
arXiv:2607. 16323v1 Announce Type: cross Abstract: Electrocardiography (ECG) is an inexpensive, standard-of-care test for cardiac symptoms, but front-line triage often lacks immediate access to definitive imaging such as echocardiography (ECHO) or cardiac magnetic resonance (CMR).
By Alexander Selivanov, Friederike Jungmann, Jan Kehrer, Karl-Ludwig Laugwitz, Eimo Martens, Daniel Rueckert
ECGQuest is a new benchmark that evaluates language models on the contextual knowledge required for electrocardiogram interpretation, featuring 10,904 True/False questions derived from 23 ECG references and 2003‑2025 Computing in Cardiology proceedings. The study tested 23 commercial and open‑source models, finding that zero‑shot accuracy ranged from 49.5% to 74.4% and that fine‑tuning with Low‑Rank Adaptation improved all open‑source models by 6.5–14.1%, with the best fine‑tuned model achieving 76.3% accuracy and a five‑model ensemble reaching 78.5%. ECGQuest demonstrates that parameter‑efficient fine‑tuning can enable smaller models to compete with larger commercial ones on ECG‑specific tasks.
By Mohammadsina Hassannia, Matthew A. Reyna, Reza Sameni
arXiv:2608. 05893v1 Announce Type: new Abstract: Electrocardiography (ECG) is one of the most widely used non-invasive tools for diagnosing cardiovascular disease, but transforming multi-lead ECG recordings into reliable clinical reports remains challenging.
By Akanta Das, Tasinul Islam Ahon, Ahmed Mahir Sultan Rumi, Md Mahbubur Rahman, Tausif Amim Shadly, Tanzima Hashem
The study investigates whether ECG representations derived from a β-variational autoencoder (VAE) can distinguish patients with myocardial scar (LGE+) from those without (LGE-) using routine ECG data. In a cohort of 300 cardiomyopathic patients, the β-VAE achieved an AUC of 0.577 (sensitivity 0.775) with Gradient Boosting, while the foundation ECGx.AI model reached an AUC of 0.686 with Random Forest. Dynamic Time Warping reconstruction errors differed significantly between classes in most leads and improved classification to an AUC of 0.643 with Logistic Regression, suggesting these errors could serve as markers of scar-related ECG changes.
By Shayan Sharifi, Riccardo Treu, Ilaria Gandin, Federico Garoia, Marco Merlo, Giulia Cisotto