ECGQuest is a new benchmark that evaluates language models on the contextual knowledge required for electrocardiogram interpretation, featuring 10,904 True/False questions derived from 23 ECG references and 2003‑2025 Computing in Cardiology proceedings. The study tested 23 commercial and open‑source models, finding that zero‑shot accuracy ranged from 49.5% to 74.4% and that fine‑tuning with Low‑Rank Adaptation improved all open‑source models by 6.5–14.1%, with the best fine‑tuned model achieving 76.3% accuracy and a five‑model ensemble reaching 78.5%. ECGQuest demonstrates that parameter‑efficient fine‑tuning can enable smaller models to compete with larger commercial ones on ECG‑specific tasks.
arXiv:2607. 16323v1 Announce Type: cross Abstract: Electrocardiography (ECG) is an inexpensive, standard-of-care test for cardiac symptoms, but front-line triage often lacks immediate access to definitive imaging such as echocardiography (ECHO) or cardiac magnetic resonance (CMR).
arXiv:2607. 20814v1 Announce Type: new Abstract: The electrocardiogram (ECG) is a cornerstone of cardiac as- sessment, yet clinical deployment of deep learning models remains con- strained by limited interpretability and the hallucination risk of large language models (LLMs).
arXiv:2608. 05893v1 Announce Type: new Abstract: Electrocardiography (ECG) is one of the most widely used non-invasive tools for diagnosing cardiovascular disease, but transforming multi-lead ECG recordings into reliable clinical reports remains challenging.
arXiv:2608. 09053v1 Announce Type: cross Abstract: Cardiologists interpret electrocardiograms by localizing waveform components, measuring rhythm and interval patterns, and translating these structured observations into diagnostic evidence.
arXiv:2607. 27404v1 Announce Type: new Abstract: Existing benchmarks for electrocardiogram foundation models primarily evaluate downstream predictive performance, providing limited insight into whether their internal representations can be faithfully decomposed, clinically interpreted, or reproduced across independent analyses.
arXiv:2605. 29977v2 Announce Type: replace-cross Abstract: High-fidelity ECG interpretation is increasingly reliant on massive foundation models, yet their deployment in clinical edge-care remains hindered by extreme computational demands.
arXiv:2608. 03597v1 Announce Type: new Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased risks of stroke, heart failure, and mortality.
arXiv:2608. 19297v1 Announce Type: new Abstract: While multimodal large language models (MLLMs) excel in medical applications, most of them favor static images or short-term signals.
Cardiologists interpret electrocardiograms by localizing waveform components, measuring rhythm and interval patterns, and translating these structured observations into diagnostic evidence. Whether this expert reading process can serve as an effective prior for ECG agents remains unclear.
The study demonstrates that contrastive pre‑training of ECG representations using cardiac magnetic resonance (CMR) imaging data can enhance ECG‑based detection of Chagas disease. By aligning an ECG encoder with a CMR embedding space from 63,193 paired UK Biobank examinations, the authors achieved higher AUROC and sensitivity metrics on CODE‑15%, SaMi‑Trop, and PhysioNet/CinC 2025 Challenge datasets compared to an unaligned baseline. The approach shows that imaging‑supervised ECG representations generalize across different populations and resource‑constrained settings.
Multimodal large language models (LLMs) are increasingly adopted to interpret 12-lead ECG images, though the interpretations often lack validation. However, ECG image understanding significantly differs from general images as it depends on precise waveform morphology, lead relationships and accurate interval measurements.
NeuroECG is a deep learning framework that repurposes a pretrained ECG foundation model to predict neurological outcomes after cardiac arrest without using electroencephalography (EEG). The model fine‑tunes the backbone with a gradual unfreezing strategy on single‑channel bedside ECG, aggregates multiple ECG segments via quantile pooling and PCA, and achieves an AUROC of 0.7333 using ECG alone. When combined with static clinical covariates, NeuroECG improves performance to an AUROC of 0.8077 and an AUPRC of 0.8970, demonstrating that bedside ECG can serve as a low‑cost, auxiliary prognostic tool in an EEG‑free setting.