The paper introduces the first adaptation of the MedSAM2 foundation model for interactive 3D segmentation of interstitial lung disease (ILD) on thoracic CT scans. It evaluates three fine‑tuning strategies and four prompt types—bounding‑boxes, points, lassos, and scribbles—finding that full model fine‑tuning yields the best performance, improving Dice scores by 4.7 percentage points over the baseline. A proof‑of‑concept workflow is presented where MedSAM2 is first initialized with an automatic prior and then refined by radiologist prompts, with all resources released on GitHub.
arXiv:2608. 00195v1 Announce Type: cross Abstract: High-resolution 3D segmentation of hip and shoulder anatomy from CT and MRI is essential for surgical planning, yet frozen segmentation models often fail under domain shift.
arXiv:2606. 04705v1 Announce Type: cross Abstract: Semantic segmentation in medical imaging is a critical yet challenging task due to data scarcity and high variability across modalities.
arXiv:2606. 28392v1 Announce Type: cross Abstract: Accurate lesion segmentation in PET/CT is critical for oncology, yet remains challenging because physiologic tracer uptake and artifacts can mimic malignant signal.
arXiv:2606. 15611v1 Announce Type: cross Abstract: Organ segmentation from PET/CT is critical for quantitative analysis and radiotherapy planning in oncology.
The paper introduces an anatomy-aware, promptable segmentation model for whole-body lesion detection in FDG and PSMA PET/CT scans, tailored for the AUTOPET V challenge. The approach builds on nnU-Net, employing a two-stage training process: an initial pre-training phase for strong baseline segmentation and an online interactive phase that refines predictions using scribble prompts. Anatomical context is integrated via organ supervision with a shared head predicting both lesions and organs, reducing false positives, while a tracer classifier directs studies to either a combined FDG+PSMA model or a PSMA-specific model. Cross-validation results show that organ-supervised training yields the most stable performance, the interactive stage consistently improves Dice scores, and PSMA-specific training delivers the best tracer-wise results.
Organ segmentation from PET/CT is critical for quantitative analysis and radiotherapy planning in oncology. To ease the high annotation cost of PET/CT segmentation, semi-supervised learning (SSL) provides a practical and effective solution for developing deep models with limited labeled data.
arXiv:2607. 01001v1 Announce Type: cross Abstract: Radiomics is the established approach for CT-based lung cancer phenotyping, yet comparisons with foundation models rarely isolate contributions of feature extractor, classification head, and segmentation choice, or test cross-cohort robustness.
In clinical oncology studies, metastatic cancer is commonly evaluated using "Response Evaluation Criteria in Solid Tumors" (RECIST), in which the diameter of up to five lesions is measured and followed over the course of treatment. However, RECIST shows limited correlation with overall survival.
arXiv:2607. 25164v1 Announce Type: cross Abstract: A CT examination captures multiple organs, but many biomedical questions concern abnormalities, prognosis, or longitudinal change in a specific organ.
arXiv:2608. 05960v1 Announce Type: cross Abstract: Routine CT interpretation is inherently comprehensive, capturing incidental findings across the entire scan volume.
The paper introduces an unsupervised domain adaptation framework that aligns redundancy-reducing features to enable accurate 3D segmentation of cone-beam CT (CBCT) without target-domain annotations or inference-time adaptation. The method is architecture-agnostic, working with both CNN-based and ViT-based foundation models, and is evaluated on two liver segmentation benchmarks for interventional vascular procedures and radiation therapy. Results show that even large pretrained segmentation networks need explicit feature-space bridging to generalize across diagnostic CT and CBCT, and the proposed approach consistently outperforms existing pretrained foundation models and UDA strategies.
arXiv:2509. 25594v2 Announce Type: replace-cross Abstract: Medical image segmentation is fundamental to clinical decision-making, yet existing models remain fragmented.