arXiv:2609.15161v1 Announce Type: cross
Abstract: Large language model (LLM) driven multi-agent systems have shown promise in complex clinical reasoning, yet existing approaches rely on static strate...
By Dongsheng Shi, Yue Li, Xin Yi, Linlin Wang
arXiv:2607. 15314v1 Announce Type: new Abstract: Healthcare spans high-stakes communication, expert reasoning, and workflow execution, yet specialized LLMs that cover these use cases together remain limited.
By actAVA AI, :, Haolin Chen, Leon Qi, Steve Brown, Deon Metelski, Tao Xia, Joonyul Lee, Qixuan Wang, Kevin Riley, Frank Wang, Weiran Yao
The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.
By Wenliang Li, Rui Yan, Xu Zhang, Li Chen, Hongji Zhu, Jing Zhao, Junjun Li, Mengru Li, Wei Cao, Zihang Jiang, Wei Wei, Kun Zhang, Shaohua Kevin Zhou
arXiv:2608.21864v1 Announce Type: cross
Abstract: The current progress of Clinical Vision Large Language Models (C-VLLMs) has substantially improved digital diagnostics, still these frameworks often...
By Md Asaduzzaman Jabin, Zihao Wu, Tianming Liu
arXiv:2607. 09521v1 Announce Type: new Abstract: Does every cancer patient truly need a complete diagnostic workup for accurate survival prediction?
By Chongyu Qu, Can Cui, Zhengyi Lu, Junchao Zhu, Tianyuan Yao, Junlin Guo, Juming Xiong, Yanfan Zhu, Yuechen Yang, Bennett A. Landman, Yuankai Huo
arXiv:2608. 11420v1 Announce Type: new Abstract: Medical diagnostic reasoning is a high-impact use case for LLMs that carries significant implications for the health and wellbeing of users.
By Del Coburn, Scott Sanner, Dan Silver
ClinicalReTrial is a multi‑agent AI system that treats clinical trial protocol optimization as an iterative redesign problem on textual documents. It combines failure diagnosis, safety‑aware modifications, and candidate evaluation within a closed‑loop, reward‑driven framework, using a predictive model as a simulation environment for low‑cost, dense feedback. The system achieves a 56.7% conversion of failed protocols to predicted successes, with a 7.4% average success probability increase at a negligible cost, and its redesign patterns align with real‑world expert changes.
By Sixue Xing, Kerui Wu, Xuanye Xia, Haoyu He, Meng Jiang, Jintai Chen, Tianfan Fu
arXiv:2605. 09366v3 Announce Type: replace Abstract: Transforming neuroimaging data into clinically actionable biomarkers is a knowledge-intensive and labor-intensive process.
By Keqi Han, Songlin Zhao, Yao Su, Xiang Li, Yixuan Yuan, Lifang He, Carl Yang
arXiv:2603. 25821v3 Announce Type: replace-cross Abstract: We present Doctorina MedBench, an evaluation framework for agent-based medical AI based on the simulation of physician-patient interactions.
By Anna Kozlova, Stanislau Salavei, Pavel Satalkin, Hanna Plotnitskaya, Sergey Parfenyuk, Andy Nkansah
arXiv:2607. 11175v1 Announce Type: new Abstract: The growing ability of large language models and vision language models to jointly interpret and reason over images and text is reshaping medical agents, moving them from task specific predictors toward autonomous systems that perceive, reason, plan, remember, and act in clinical environments.
By Chunzheng Zhu, Lei Tian, Bohan Tan, Ziqi Zhou, Yuxuan Sun, Yijun Wang, Chengchao Lv, Yilin Wen, Yijun He, Jinghao Lin, Yihang Chen, Cheewei Tan, Qianshan Wei, Lei Zhao, Bin Pu, Kenli Li, Yuan Xue, Jianxin Lin
arXiv:2606. 02812v1 Announce Type: new Abstract: Modeling patient trajectories from longitudinal electronic health records (EHRs) requires reasoning over sparse, noisy, and long-context multimodal sequences.
By Sihang Zeng, Matthew Thompson, Ruth Etzioni, Meliha Yetisgen
arXiv:2606. 16721v1 Announce Type: new Abstract: Medical diagnosis and treatment are dynamic processes in which patient states evolve over time and clinical interventions alter future outcomes.
By Ke Liu, Mengxuan Li, Yanyi Bao, Tianyun Zhang, Chong Chu, Jiajun Bu, Haishuai Wang