arXiv:2610. 40662v1 Announce Type: cross Abstract: HER2 status decides who receives HER2-targeted therapy.
Machine-generated by The Flow from the publisher's headline and feed description — not written or checked by a human. The full article lives at arXiv Machine Learning.
arXiv:2610.33081v1 Announce Type: new Abstract: Generalist segmenters such as Cellpose-SAM (CPSAM) outline cells accurately across stains but slowly; watershed detectors such as QuPath's are fast but...
arXiv:2608.22059v1 Announce Type: cross Abstract: Pretrained image encoders are central to medical image classification, where expert annotation is costly and task-specific cohorts are often limited....
arXiv:2602. 14010v2 Announce Type: replace-cross Abstract: Pathology foundation models (PFMs) generalize well across computational pathology tasks but remain costly for gigapixel whole-slide image analysis.
TAP-Path is a task‑adaptive compression framework that restructures a pretrained Virchow2 encoder for histopathology. It selectively removes transformer blocks, prunes patch tokens, and adds a lightweight gated task head, reducing parameters by 24.96% and FLOPs by 35.20% while maintaining high accuracy on a 32‑class benchmark. The method achieves competitive test metrics and improved rare‑class performance, with strong external validation on CPTAC samples.
The study evaluates 15 frozen hematology foundation-model embeddings across four single‑cell acquisition domains, finding that while in‑domain accuracy is near‑saturated (macro‑F1 0.98–0.997), cross‑dataset performance drops dramatically (34–72%) and model rankings shift. Probe‑dependent rank transfer is observed, with 1‑NN retrieval more stable than linear heads, yet neither reliably predicts target robustness. Calibration deteriorates off‑domain (ECE rises from 0.004 to 0.35), and exposure to internal cohorts confounds shift analysis; a training‑free pseudo‑label‑balanced feature normalization (CBR) modestly improves target‑prior robustness and calibration. whyItMatters":"The findings highlight that frozen hematology foundation models, though accurate in‑domain, may fail under realistic scanner, site, and class‑prior shifts, underscoring the need for comprehensive audits of accuracy, calibration, exposure, and robustness before clinical deployment."
DistillPath-KS16 is a 22‑million‑parameter ViT‑S/16 pathology encoder distilled from larger teachers ranging from 86 M to 1.1 B parameters. By training only on the teachers’ final class and patch tokens across 6,000 public slides, it avoids costly pretraining heads and large tile corpora, yet surpasses the kaiko baseline on EVA, HEST, and PLISM benchmarks. The strongest variant, DistillPath-KS16‑Virchow2, achieves a mean EVA score of 0.795—just 0.015 points below the top model—while being 29× smaller and 25× faster.