arXiv:2602. 14010v2 Announce Type: replace-cross Abstract: Pathology foundation models (PFMs) generalize well across computational pathology tasks but remain costly for gigapixel whole-slide image analysis.
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TAP-Path is a task‑adaptive compression framework that restructures a pretrained Virchow2 encoder for histopathology. It selectively removes transformer blocks, prunes patch tokens, and adds a lightweight gated task head, reducing parameters by 24.96% and FLOPs by 35.20% while maintaining high accuracy on a 32‑class benchmark. The method achieves competitive test metrics and improved rare‑class performance, with strong external validation on CPTAC samples.
LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.
arXiv:2608.28708v1 Announce Type: cross Abstract: Prospective silent trials provide an important bridge between retrospective validation of artificial intelligence (AI) models and their use in clinic...
arXiv:2607. 18218v1 Announce Type: cross Abstract: Foundation models have emerged as a driving force in computational pathology, with the potential to transform cancer diagnosis, prognosis, and treatment selection by learning transferable representations from large-scale histopathology data.
arXiv:2607. 22861v1 Announce Type: cross Abstract: Pathology foundation models (FMs) produce powerful tile-level representations which remain sensitive to scanner and staining variability, undermining deployment across laboratories.
Lumen is a pathology vision‑language model that aligns frozen unimodal foundation models (Virchow2 and BioMedBERT) using rank‑4 adapters and projection heads, training only 0.40% of the total parameters on the QUILT‑1M corpus. It achieves the highest mean chance‑corrected balanced accuracy (0.546) across nine zero‑shot patch benchmarks and demonstrates strong performance on lymph‑node metastasis detection, with AUROC scores of 0.964 internally and 0.955 externally. While it ranks third in cross‑modal retrieval, Lumen’s low‑parameter training yields competitive results at both patch and slide levels.