arXiv Machine Learning

Generative Augmentation of Raman Spectra for Glioma Classification

arXiv:2607. 10196v1 Announce Type: new Abstract: Access to sufficiently large biomedical datasets remains a major obstacle for machine learning in Raman spectroscopy-based diagnostics.

arXiv Machine Learning
Aug 28

MODIS: Multi-Omics Data Integration for Small and unpaired datasets

MODIS is a semi‑supervised framework for integrating multi‑omics data that are often unpaired, partially labeled, and scarce, such as in rare disease studies. It trains on a large reference database and a small target dataset simultaneously, using diagonal integration and class‑label alignment to handle class imbalance. The architecture combines variational auto‑encoders, a class classifier, and an adversarially trained modality classifier, with a regularized relativistic GAN loss for stable training, and demonstrates high accuracy on synthetic data and the TCGA cancer dataset.

By Daniel Lepe-Soltero, Thierry Arti\`eres, Ana\"is Baudot, Paul Villoutreix
arXiv Machine Learning
Jun 15

Machine Learning for Biomedical Raman Spectroscopy: From Spectral Acquisition to Clinical Translation

arXiv:2606. 14169v1 Announce Type: new Abstract: Raman spectroscopy provides label-free, chemically specific characterization of biological systems and has become an important tool for cancer diagnosis, molecular subtyping, microbiological identification, and intraoperative decision support.

By Bogdan Oancea, Ana Maria Seciu-Grama, Nicoleta Siminea, Laura Mihaela Stefan, Alice Stoica, Joel Sjoberg, Marian Necula, Ana-Maria Prelipcean, Corneliu Ovidiu Vrancianu, Eduard Milea, Andrei P\u{a}un, Ion Petre, Mihaela P\u{a}un
Hugging Face Trending Papers
Jun 17

A Controlled Benchmark of Quantum-Latent GAN Augmentation for Brain MRI

Medical image classification is often constrained by limited labeled data, motivating generative augmentation; recently, quantum generative models have been proposed for this purpose, frequently reporting accuracy gains. However, such claims are typically based on single training runs, do not match the parameter budgets of the quantum and classical generators, and do not characterize the data regime in which any benefit appears.

arXiv Computer Vision
Sep 25

Does DCGAN-Based Synthetic Augmentation Improve Brain Tumor MRI Classification? An Empirical Study

This study examined whether augmenting brain tumor MRI datasets with class‑specific DCGAN‑generated images improves classification performance. Using 7,200 scans across four tumor categories, a Swin Transformer classifier trained on real images alone achieved 96% accuracy, identical to the model trained with 500 synthetic images per class. Metrics such as macro F1 and ROC‑AUC showed no improvement, and FID scores indicated substantial distributional differences between real and synthetic images.

By Irhum Jawad Khan, Talha bin Aslam
arXiv Machine Learning
Sep 18

Sharpness-Aware Minimization (SAM) Improves Classification Accuracy of Bacterial Raman Spectral Data Enabling Portable Diagnostics

Sharpness-Aware Minimization (SAM) is applied to improve the generalization of machine learning models for classifying bacterial Raman spectra, a technique that could enable rapid, portable diagnostics for antimicrobial resistance. The study shows that SAM can increase classification accuracy by up to 10.5% on a single data split and by an average of 2.7% across multiple splits compared to the traditional Adam optimizer. These gains demonstrate SAM’s potential to enhance the clinical utility of AI-powered Raman spectroscopy tools.

By Kaitlin Zareno, Jarett Dewbury, Siamak K. Sorooshyari, Hossein Mobahi, Loza F. Tadesse