arXiv AI

BioHiCL: Hierarchical Multi-Label Contrastive Learning for Biomedical Retrieval with MeSH Labels

arXiv:2604. 15591v2 Announce Type: replace-cross Abstract: Effective biomedical information retrieval requires modeling domain semantics and hierarchical relationships among biomedical texts.

arXiv Machine Learning
Aug 6

Neighborhood-Aware Dual Biomedical Entity Linking

arXiv:2608. 04144v1 Announce Type: cross Abstract: Biomedical entity linking grounds mentions in clinical and scientific text to entities in a curated knowledge base (KB) with ontological structure, which supports downstream applications such as literature-scale information extraction and patient-record normalization.

By Yicheng Tao, Jie Liu
arXiv AI
Sep 3

BioELX: Context-Aware Cross-lingual Biomedical Entity Linking without Task-Specific Supervision

BioELX is a retrieve‑rerank framework for cross‑lingual biomedical entity linking that tackles two key problems: the English‑biased UMLS alias training data and the degradation caused by naïvely adding context. It fine‑tunes SapBERT_multi with Wikidata‑derived cross‑lingual alias supervision to create shared concept neighborhoods, and then reranks candidates using pretrained LLMs with mention‑anchored prompting to focus on the target mention. Experiments demonstrate state‑of‑the‑art performance on four benchmarks, improving Recall@1 by 4.8–18.2 percentage points without task‑specific annotations.

By Yi Wang, Corina Dima, Liangyu Zhong, Steffen Staab
arXiv Machine Learning
Aug 18

Retrieval-guided Twin Fusion with Similarity-aware Contrast for Molecule-Text Alignment

arXiv:2608. 16005v1 Announce Type: new Abstract: This paper studies the problem of molecule-text alignment, which aims to project molecules and their textual descriptions into a joint latent space for downstream tasks including molecule search and molecular property prediction.

By Shunshun Gu, Shengqi Qiu, Hang Zhou, Xiao Luo
arXiv AI
3d ago

Overview of BioASQ 2026: The fourteenth BioASQ Challenge on Large-Scale Biomedical Semantic Indexing and Question Answering

arXiv:2609.39975v1 Announce Type: cross Abstract: This paper presents an overview of the fourteenth edition of the BioASQ challenge, organized in the context of the Conference and Labs of the Evaluat...

By Anastasios Nentidis, Georgios Katsimpras, Anastasia Krithara, Martin Krallinger, Miguel Rodr\'iguez-Ortega, Eduard Rodriguez-L\'opez, Natalia Loukachevitch, Igor Rozhkov, Elena Tutubalina, Dimitris Dimitriadis, Vasiliki Patsiou, Grigorios Tsoumakas, George Giannakoulas, Alexandra Bekiaridou, Athanasios Samaras, Giorgio Maria Di Nunzio, Nicola Ferro, Stefano Marchesin, Marco Martinelli, Gianmaria Silvello, Georgios Paliouras
arXiv AI
Aug 28

MedFG-VQA: Low-Frequency Memory and Graph Attention for Lightweight Medical VQA

MedFG-VQA is a lightweight medical visual question answering framework that uses a memory bank to enhance low‑frequency DCT features and graph‑enhanced cross‑attention for visual‑textual alignment. It introduces Frequency‑Memory Fusion to retrieve and fuse low‑frequency information from a learnable memory bank, and Graph‑Aware Cross‑Attention to refine cross‑modal features via graph convolution. The authors also create SynMed‑VQA, a synthetic dataset of over 2 million QA pairs across nine imaging modalities, and show that MedFG‑VQA matches or outperforms larger models on several biomedical VQA benchmarks while keeping computational costs low.

By Haowen Gu, Gensheng Pei, Zeren Sun, Mingwu Ren, Xiangbo Shu, Yazhou Yao, Fumin Shen
arXiv Machine Learning
Aug 28

Modular Expert Merging for Biomedical Retrieval

The paper proposes a method called Modular Expert Merging for Biomedical Retrieval, which combines independently trained domain‑specialized experts instead of large mixed‑domain training. Experiments across four decoder‑only LLM families (0.6B‑7B) and twelve retrieval tasks from MTEB show that merging experts consistently outperforms mixed‑domain training. The authors also introduce a Synthesize‑Train‑Merge (STM) framework that generates hard negatives with a top‑tier LLM, fine‑tunes experts via LoRA, and merges them, achieving strong biomedical retrieval performance while retaining competitive general‑domain results.

By Sameh Khattab, Jean-Philippe Corbeil, Osman Alperen \c{C}inar-Kora\c{s}, Amin Dada, Julian Friedrich, Jiawei He, Douglas Teodoro, Jens Kleesiek
arXiv AI
Jul 13

TheBioCollection: Unified Pre-Training Scale LLM Corpus for Biology

arXiv:2607. 08803v1 Announce Type: cross Abstract: The push toward large language models for biology (BioLM) has created a need for training corpora that can endow models with a genuine understanding of biology.

By Hyunjin Seo, Hyeon Hwang, Gyubok Lee, Jay Shin, Jimin Park, Taesoo Kim, Sanghoon Lee, Hongjoon Ahn, Sungjun Han, Sangwon Jung
arXiv AI
6d ago

HCOE: Hyperbolic Clinical Ontology Embeddings from Biomedical Language Models

The paper introduces Hyperbolic Clinical Ontology Embeddings (HCOE), a method that transforms frozen BioBERT embeddings into a Poincaré ball to capture medical code hierarchies. HCOE employs ontology-guided contrastive learning and coarse‑to‑fine ontology‑path aggregation, leveraging ICD, CCS, and ATC hierarchies. Experiments on MIMIC‑IV demonstrate superior performance in clinical relation prediction, hierarchy transfer, and various predictive tasks such as mortality, readmission, medication recommendation, and rare drug prediction.

By Yixuan Li, Weihao Li, Ziyang Song
arXiv AI
Jun 8

MMBU: A Massive Multi-modal Biomedical Understanding Benchmark to Probe the Perception Capabilities of Vision-Language Models

arXiv:2606. 06696v1 Announce Type: cross Abstract: Vision and language models (VLMs) hold immense promise to transform biomedical imaging workflows, from detecting lesions in chest X-rays to profiling cellular features in microscopy.

By Ryan D'Cunha, Alejandro Lozano, Xiaoxiao Sun, Daniel Vela Jarquin, Min Woo Sun, Josiah Aklilu, James Burgess, Yuhui Zhang, Ryan Nayebi, Paola Avila, Robayo, Jin Ye, Ming Hu, Zhongying Deng, Junjun He, Xin Chen, Yue Yao, Robert Tibshirani, Jeffrey J. Nirschl, Serena Yeung-Levy