arXiv Machine Learning

Neighborhood-Aware Dual Biomedical Entity Linking

arXiv:2608. 04144v1 Announce Type: cross Abstract: Biomedical entity linking grounds mentions in clinical and scientific text to entities in a curated knowledge base (KB) with ontological structure, which supports downstream applications such as literature-scale information extraction and patient-record normalization.

arXiv Computation and Language
Sep 23

BELXTR: Biomedical Entity Linking via Contextualized Token Retrieval

BELXTR is a new biomedical entity linking model that uses a multi‑vector (late interaction) architecture to preserve token‑level matching information, unlike traditional embedding‑based approaches that compress mentions into a single vector. By extending the XTR model with a task‑specific training objective and active query expansion, BELXTR achieves state‑of‑the‑art performance on half of ten evaluated corpora, with an average 5‑percentage‑point gain in recall@1. The model shows especially strong results on cross‑species gene disambiguation, outperforming an LLM‑powered retrieve‑and‑rerank pipeline and approaching a specialized rule‑based system.

By Samuele Garda, Ulf Leser
arXiv AI
Sep 3

BioELX: Context-Aware Cross-lingual Biomedical Entity Linking without Task-Specific Supervision

BioELX is a retrieve‑rerank framework for cross‑lingual biomedical entity linking that tackles two key problems: the English‑biased UMLS alias training data and the degradation caused by naïvely adding context. It fine‑tunes SapBERT_multi with Wikidata‑derived cross‑lingual alias supervision to create shared concept neighborhoods, and then reranks candidates using pretrained LLMs with mention‑anchored prompting to focus on the target mention. Experiments demonstrate state‑of‑the‑art performance on four benchmarks, improving Recall@1 by 4.8–18.2 percentage points without task‑specific annotations.

By Yi Wang, Corina Dima, Liangyu Zhong, Steffen Staab
arXiv Computation and Language
Sep 10

OntologyAligner: Ontology-Aligned Retrieval and Hierarchy-Guided Large Language Model Reranking for Biomedical Ontology Normalization

arXiv:2609.10055v1 Announce Type: cross Abstract: Biomedical ontology normalization maps free-text expressions to standardized concepts, enabling consistent integration and analysis of biomedical dat...

By Jie Song, Zhichuan Xu, Ziyu Lu, Meng Xiao, Cheng Bi, Yuxin Zhang, Xin Zheng, Xiaoran Li, Qiongfang Cao, Hao Yang, Bairong Shen
arXiv AI
Sep 10

Building evidence-based knowledge bases from full-text literature for disease-specific biomedical reasoning

EvidenceNet is a disease‑specific dataset that transforms full‑text biomedical literature into structured evidence records and graph representations, preserving study design, provenance, and quantitative support. Using an LLM‑assisted pipeline, it extracts experimentally grounded findings, normalizes entities, scores evidence quality, and links related records via typed semantic relations. The released subsets—EvidenceNet‑HCC and EvidenceNet‑CRC—contain thousands of evidence records and richly connected graphs, with high extraction and relation‑type accuracy, enabling retrieval‑augmented question answering and graph‑based tasks such as link prediction and target prioritization.

By Chang Zong, Jinyu Chen, Sicheng Lv, Si-tu Xue, Huilin Zheng, Jian Wan, Lei Zhang
arXiv Machine Learning
Jun 2

GRASP: Plan-Guided Graph Retrieval with Adaptive Fusion and Reranking on Semi-Structured Knowledge Bases

arXiv:2605. 30237v2 Announce Type: replace-cross Abstract: Semi-structured knowledge bases (SKBs) embed textual documents in a typed graph of entities and relations, and underpin applications such as product search, academic paper search, and precision-medicine inquiries.

By Yicheng Tao, Yiqun Wang, Xiangchen Song, Xin Luo, Kai Liu, Jie Liu
arXiv Machine Learning
Sep 2

Hidden relationships in a document-derived property graph: top-k chunk embeddings and inverse-distance weighting over a dynamically evolving ontology

The paper introduces a second-pass method for uncovering hidden relationships in knowledge graphs extracted from text, without altering the original facts. By chunking documents and embedding each chunk once, the approach uses top‑k nearest‑neighbor queries and Shepard inverse‑distance weighting to score candidate node pairs, avoiding threshold issues inherent in cosine scoring. The technique is order‑independent, scalable, and has been implemented across multiple graph databases, demonstrating high edge fidelity with lower‑dimensional embeddings and a 25× speedup in top‑k computation.

By Bilge Kaan Karamete, Hunter Casten
arXiv Computation and Language
Sep 22

Custom Named Entity Recognition and Topic Classification for Global Health Publications

This thesis explores how to select and adapt NLP models for global health literature when annotated data and computational resources are scarce. It compares skip‑gram word2vec models trained on increasingly large specialized corpora with BioWordVec for semantic tag discovery, finding that larger coverage does not always yield more useful domain associations. The study also evaluates convolutional spaCy models versus a RoBERTa transformer for named entity recognition, noting a trade‑off between higher F1 scores and longer inference time, and investigates MiniLM few‑shot versus BART‑MNLI zero‑shot classification for multi‑label topic classification, highlighting practical constraints of inference cost. "whyItMatters":"The work provides empirical guidance on balancing model accuracy and resource demands for building knowledge systems in low‑resource global health settings."

By Genis Skura, Antoine Geissb\"uhler, Jean-Luc Falcone
arXiv AI
Sep 17

SNOMED CT Concept Recommendation from Masked Clinical Context

The paper introduces a benchmark for recommending SNOMED CT concepts from masked clinical contexts, using data from the SNOMED CT Entity Linking Challenge v1.2.1 derived from MIMIC-IV-Note. It evaluates several methods—including a popularity baseline, sparse TF‑IDF prototypes, dense embeddings, and retrieval‑augmented hybrids—finding that sparse TF‑IDF achieves the best performance with Recall@1 of 14.81% and Recall@10 of 33.43%. The study highlights that concept frequency and lexical context strongly influence recommendation quality, with many test pairs involving concepts unseen during training.

By Ali Noori
arXiv AI
Sep 15

Discovering Hierarchy-Grounded Domains with Adaptive Granularity for Clinical Domain Generalization

The paper introduces UdonCare, a hierarchy‑pruning method that iteratively partitions patients into latent domains using medical ontologies, aiming to improve domain generalization in clinical prediction tasks. It addresses challenges of missing domain labels and lack of clinical insight by discovering hierarchy‑grounded patient domains. Experiments on MIMIC‑III, MIMIC‑IV, and eICU datasets show UdonCare outperforms eight baseline methods across four prediction tasks with significant domain gaps.

By Pengfei Hu, Xiaoxue Han, Fei Wang, Yue Ning