arXiv:2606. 08483v1 Announce Type: new Abstract: Background: Consumer-facing large language models are now a common source of health information, and they interpret and personalize responses rather than retrieve them.
By Rahul Gorijavolu, Kaushik Madapati, Pritika Vig, Rawan Abulibdeh, Nikhil Jaiswal, Mahri Kadyrova, Zeamanuel Hailu Tesfaye, Charles Senteio, Paula Maurutto, Leo Anthony Celi
MIRA is a bilingual benchmark that evaluates whether large language models (LLMs) provide consistent medical information across different user phrasings, languages, and health literacy levels. It contains 4,320 prompts derived from 60 medically reviewed low‑risk health questions and reveals that models tend to omit key information and offer fewer concrete next steps when responding to low health‑literacy signals, a phenomenon termed Differential Information Dilution (DID). A knowledge‑guided mitigation prompt can reduce this dilution for most models, notably improving Claude and Qwen.
By Mengyu Xu, Qiaoxin Yang, Qianqian Wang, Xiwei Dai, Weiyi Wu, Chongyang Gao
arXiv:2608. 12138v1 Announce Type: cross Abstract: General-purpose large language models (LLMs) have recently been reported to match or exceed specialized clinical AI tools on medical benchmarks, but such comparisons draw on a narrow set of systems and on benchmarks developed largely in high-income settings.
By Praveen Reddy, Charuta Mandke, Suvrankar Datta, Sarah Khan, Siddharth Reddy Anthireddy, Shitij Arora, Vishal Singh
arXiv:2604. 14892v3 Announce Type: replace-cross Abstract: Evaluating medical AI systems using expert clinician panels is costly and slow, motivating the use of large language models (LLMs) as alternative adjudicators.
By Amy Rouillard, Sitwala Mundia, Linda Camara, Ziyaad Dangor, Michael Cameron Gramanie, Ismail Kalla, Shabir A. Madhi, Kajal Morar, Marlvin T. Ncube, Haroon Saloojee, Bruce A. Bassett
arXiv:2512. 01241v3 Announce Type: replace-cross Abstract: Large language models (LLMs) are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.
By David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain, Jessica Tran, Matthew Gwiazdon, Arjun Rustagi, Jenelle Jindal, Jacob M. Koshy, Vinay Kadiyala, Anup Agarwal, Bassman Tappuni, Brianna French, Sirus Jesudasen, Christopher V. Cosgriff, Rebanta Chakraborty, Jillian Caldwell, Susan Ziolkowski, David J. Iberri, Robert Diep, Rahul S. Dalal, Kira L. Newman, Kristin Galetta, J. Carl Pallais, Nancy Wei, Kathleen M. Buchheit, David I. Hong, Vartan Pahalyants, Ernest Y. Lee, Allen Shih, Tamara B. Kaplan, Vishnu Ravi, Sarita Khemani, Thomas A. Buckley, April S. Liang, Daniel Shirvani, Advait Patil, Nicholas Marshall, Kanav Chopra, Joel Koh, Adi Badhwar, Anastasia Perez, Austin J. Schoeffler, Mahbuba Tusty, Chase M. Walton, Liam G. McCoy, David J. H. Wu, Yingjie Weng, Sumant Ranji, Kevin Schulman, Nigam H. Shah, Jason Hom, Arnold Milstein, Arjun K. Manrai, Adam Rodman, Jonathan H. Chen, Ethan Goh
arXiv:2601. 17642v2 Announce Type: replace Abstract: Safety alignment in Large Language Models is critical for healthcare; however, reliance on binary refusal boundaries often results in over-refusal of benign queries or unsafe compliance with harmful ones.
By Zhihao Zhang, Liting Huang, Guanghao Wu, Preslav Nakov, Heng Ji, Usman Naseem
arXiv:2609.14819v1 Announce Type: cross
Abstract: Large language models (LLMs) have a growing range of applications in medicine, and their evaluation is critical for ensuring they provide benefit and...
By Suzannah E McKinney, Phuc Vu, Samuel A Justice, Christopher Humphries, Alyssa Pradhan, Timothy J Keyes, Bernardo C Bizzo, Keith J Dreyer, Sarah F Mercaldo, James M Hillis
arXiv:2507. 02983v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) hold significant promise for transforming digital health by enabling automated medical question answering.
By Mohammad Anas Azeez, Rafiq Ali, Ebad Shabbir, Zohaib Hasan Siddiqui, Gautam Siddharth Kashyap, Jiechao Gao, Usman Naseem
arXiv:2607. 20453v1 Announce Type: cross Abstract: Large language models show promise for clinical prediction, but zero-shot performance on specialized tasks is limited by incomplete domain knowledge, especially for smaller locally deployable models.
By Jessica Sena, Shesadree Priyadarshani, Miguel Contreras, Bharat Gandhi, Scott Siegel, Subhash Nerella, Parisa Rashidi
HerHealthEval is a controlled evaluation framework that tests multilingual understanding of women's-health communication across English, French, and Modern Standard Arabic. It provides six communicative forms—canonical, clinical, layperson, indirect or hedged, emotionally concerned, and deliberately under-specified—each conveying the same clinical concern except the under-specified form omits details to assess clarification needs. The study evaluates multilingual instruction models and QLoRA-adapted variants on tasks such as concern classification, risk calibration, clarification behavior, parse compliance, and cross-form consistency, revealing that high aggregate accuracy can mask safety-relevant failures and that language-invariant risk labels improve performance.
By Hassan Saeed Hassan Albattra, Mazen Mohammed Bahgat, Rahatara Ferdousi, Hana Essam Sayed Ahmed Amrya, Mariam Mousa
arXiv:2607. 12336v1 Announce Type: cross Abstract: Artificial Intelligence (AI) technologies, while serving as a foundational enabler for modern social media and digital health services, exert a bivalent effect by simultaneously acting as a combatant against and a spread vector for misinformation.
By Farnaz Farid, Raihan Alam, Al Al-Areqi, Farhad Ahamed, Muhammad Hassan Khan, Sadia Hossain, Irena Veljanova, Anika Tabassum Binte Hossain
arXiv:2608.22797v1 Announce Type: new
Abstract: Background This study was designed to evaluate whether a domain-specific large language model (LLM) trained exclusively on patient education resources...
By Alexander J. Hish, Arjun Nagendran, Scott N. Compton