arXiv Statistics ML

Random Hazard Forests

Random Hazard Forests (RHF) is a survival tree ensemble that models how a patient's hazard changes over continuous time as new measurements arrive. RHF directly estimates a nonparametric hazard likelihood for predictable covariate processes, using an efficient working model to guide tree construction and then estimating flexible time‑varying hazards at each terminal node. By routing each tree based on the covariate state immediately before each time point, RHF can handle irregular and asynchronous covariate updates, and averaging across trees yields a pathwise hazard estimate that accurately captures changing risk in simulations and an intensive‑care application.

arXiv AI
3d ago

PGP-Clinical-TimeKAN: Prior-Guided Joint Probabilistic Forecasting of Clinical Trajectories

PGP-Clinical-TimeKAN is a trajectory-first framework for joint probabilistic forecasting of multivariate physiological data, combining missingness-aware temporal encoders, a soft organ-system prior, patient-specific relations, nonlinear Kolmogorov‑Arnold messages, and a low‑rank multivariate Student‑t head. Evaluated on a MIMIC‑IV cohort of 6,882 patients, it achieves the second‑lowest normalized MAE and the lowest RMSE among 13 models, while providing calibrated probabilistic forecasts with empirical coverage at 50%, 80%, and 95% intervals. Ablation studies show that relational structure is critical for performance, and increasing covariance rank improves likelihood but not point accuracy. whyItMatters":"The model demonstrates that joint trajectory forecasting can yield highly accurate, calibrated predictions of physiological trajectories, offering a potentially inspectable intermediate task for clinical deterioration prediction."

By Weizhi Nie, Rihao Chang, Weijie Wang, Yuting Su
arXiv AI
Aug 11

Communication-efficient distributed hazard difference estimation for heterogeneous multi-site survival data

arXiv:2601. 14609v2 Announce Type: replace-cross Abstract: Multi-site collaboration can power survival models that no single hospital could fit alone, but privacy rules and protected computing environments block patient-level data sharing and the persistent server connections required by iterative federated methods.

By Ziwen Wang, Siqi Li, Marcus Eng Hock Ong, Nan Liu
arXiv Machine Learning
Aug 19

Mr.Dec: Daily-Scale Longitudinal Multimodal Modeling for 30-Day Readmission Prediction

Mr.Dec is a new Transformer‑decoder model that predicts 30‑day hospital readmission by treating each admission as a chronological sequence of daily multimodal events, integrating Electronic Health Record updates and Chest X‑ray findings. It uses disease‑specific supervised contrastive learning to shape a diagnosis‑aware latent space and preserves day‑level clinical signals that other methods often compress. Experiments on MIMIC‑IV and MIMIC‑CXR datasets show state‑of‑the‑art performance and the model can highlight "Critical Days" for actionable real‑time risk stratification.

By Minjun Kim, Jong Hak Moon
arXiv AI
Sep 1

Scalable Clinical Data Infrastructure and Comparative ML Evaluation for Hospitalisation Risk Prediction in Elderly Patients with Multiple Long-Term Conditions using CPRD

arXiv:2608.29419v1 Announce Type: cross Abstract: Deep learning architectures are increasingly proposed for patient trajectory modeling in electronic health records (EHRs), yet their advantage over s...

By Asra Aslam, Volodymyr Chapman, Maurice M. O'Connell, Aseel S. Abuzour, Michael Abaho, Danushka Bollegala, Gary Leeming, Eduard Shantsila, Andrew Clegg, Lauren E. Walker, Iain Edward Buchan, Samuel D. Relton