The paper introduces VERID, a semantic digital twin for laboratory workcells that bridges AI agent reasoning with the physical realities of wet labs. VERID offers queryable introspection, time‑compressed simulation, trace persistence, and a safe execution framework, enabling agents to detect errors, recover mid‑run, and validate protocols in silico. Three case studies with dye and water mixtures demonstrate VERID’s ability to pre‑emptively catch critical errors, recover from failures, and provide structured multimodal data for downstream analysis and agent training.
arXiv:2606. 31763v1 Announce Type: new Abstract: Autonomous wet-lab experimentation requires more than plausible protocol text: biological intent, quantitative procedures, device constraints and experimental feedback must remain aligned from protocol and SOP design to code and physical execution.
BEAKER is a new benchmark for evaluating embodied actionability, knowledge, experimentation, and reasoning in self‑driving chemical laboratories. It contains 1,000 expert‑curated question‑answer pairs across 11 image and video task types, covering affordance grounding, trajectory planning, equipment and state recognition, safety, apparatus setup, operation, step reasoning, and temporal procedure reasoning. The benchmark is manually created and reviewed by chemistry and embodied AI experts, and it tests 28 different multimodal large language models in an offline, single‑turn setting.
arXiv:2601. 21570v2 Announce Type: replace Abstract: The field of Embodied AI is witnessing a rapid evolution toward general-purpose robotic systems, fueled by high-fidelity simulation and large-scale data collection.
arXiv:2605. 07306v2 Announce Type: replace-cross Abstract: Biological laboratory automation can reduce repetitive manual work and improve reproducibility, but reliable embodied execution in wet-lab environments remains challenging.
arXiv:2610.18933v1 Announce Type: cross Abstract: Modern coding agents are fundamentally reshaping the role of human input for computational research: they write code, launch in silico experiments, a...
arXiv:2607.03863v3 Announce Type: replace Abstract: Artificial intelligence has advanced scientific discovery, but most AI4Science systems remain fragmented tools that rely on humans to coordinate pr...
arXiv:2606. 26722v1 Announce Type: new Abstract: The automation of scientific discovery has reached an inflection point.
LabFactory is a framework that transforms a scientific brief into an executable AI lab, integrating models, knowledge resources, tools, and a controller behind a fixed interface. The builder packages the lab in a metered workspace, and a separate host evaluates the delivered artifact on held‑out inputs, ensuring the system itself is the evaluation target. Across 28 constructions in seven scientific domains, the delivered labs surpassed reference values on all 33 subtests, demonstrating that an AI agent can fully realize a scientific brief into a working, inspectable lab.
arXiv:2606. 20120v1 Announce Type: cross Abstract: Biological experiment protocols are written in natural language, whereas automation systems rely on predefined control commands, creating a semantic gap that limits autonomous execution.
OSWorld-Science is a benchmark and evaluation environment for computer-using agents that use visual language models (VLMs) to perform scientific software tasks. It includes 12 VLMs and 146 high-quality tasks across domains such as molecular drawing, pathology image analysis, statistical computing, and physical simulation, with artifact-based evaluation and a harness that logs interactions and supports model comparison. The benchmark was developed through expert proposals and iterative human–AI co‑design, and results show that current VLMs still struggle with key scientific questions, offering insights into factors like language, reasoning, and context length.
La Agente ’Optima is an agentic framework that builds and manages Bayesian optimization campaigns for self‑driving laboratories, separating large language model reasoning from campaign execution. It maintains a persistent optimization state, allowing consistent repetitive loops and auditable decisions, and only returns control to the agent when interpretation or revision is needed. In tests on digital discovery tasks and physical platforms, it corrected measurement failures, improved yields, and recommended formulation changes, outperforming human‑directed campaigns in cost and material usage.
arXiv:2606. 12736v1 Announce Type: new Abstract: AI agents are increasingly being developed to accelerate scientific discovery, yet their practical capabilities in real research settings remain poorly understood.