arXiv AI

Socratic agents for autonomous scientific discovery in high-dimensional physical systems

arXiv:2606. 26722v1 Announce Type: new Abstract: The automation of scientific discovery has reached an inflection point.

arXiv AI
Aug 13

Mechanist: AI as a Scientific Instrument for Discovering the Mechanisms of Intelligence

arXiv:2608. 12036v1 Announce Type: new Abstract: AI models have achieved remarkable success across diverse domains, yet the mechanisms underlying their capabilities and the risks they may pose remain poorly understood.

By Mengru Wang, Junfeng Fang, Shuofei Qiao, Zhenqian Xu, Haoming Xu, Haoxiong Wang, Shumin Deng, Linyi Yang, Zhixiang Cui, Xin Xu, Yunzhi Yao, Buqiang Xu, Fei Shen, Haozhe Luo, Yunxiang Wei, Ningyu Zhang, Julian McAuley, Tat Seng Chua, Huajun Chen
arXiv AI
Sep 7

La Agente \'Optima: Towards Agentic Self-Driving Laboratories

La Agente ’Optima is an agentic framework that builds and manages Bayesian optimization campaigns for self‑driving laboratories, separating large language model reasoning from campaign execution. It maintains a persistent optimization state, allowing consistent repetitive loops and auditable decisions, and only returns control to the agent when interpretation or revision is needed. In tests on digital discovery tasks and physical platforms, it corrected measurement failures, improved yields, and recommended formulation changes, outperforming human‑directed campaigns in cost and material usage.

By Marcel M\"uller, Jiaru Bai, Willi Gottstein, Abhijoy Mandal, Mohammad Nazeri, Elia Savino, Yanlin Fang, Sujoy Das, Sergio Pablo Garc\'ia Carrillo, Yeonghun Kang, Juan B. P\'erez-S\'anchez, Simone Pilon, Martin Fitzner, Timothy No\"el, Frank Gu, Varinia Bernales, Al\'an Aspuru-Guzik
arXiv AI
Sep 10

Human-agent discovery of reconfigurable in-plane ferroelectric superdomain control

The paper introduces the Scanning Probe Agentic Research Cycle (SPARC), a framework where a coding agent and a human operator collaboratively control a microscope, sharing data and persistent memory files. SPARC was applied to reconfigure the in‑plane superdomain direction of a (111)-oriented PbZr0.2Ti0.8O3 film, demonstrating that spatial polarity alternation governs directional selection and enabling the printing of the letters UTK into the superdomain orientation. The study also identifies practical requirements for agentic experimentation, such as physical verification of instrument execution and validation of new observables.

By Yu Liu, Boris Slautin, Ching-Che Lin, Jaegyu Kim, Lane W. Martin, Sergei V. Kalinin
arXiv AI
Jun 9

Self-Evolving Scientific Agent Discovers Generalizable Physically-Reasoned Fluid Control

arXiv:2606. 08405v1 Announce Type: new Abstract: While data-intensive deep reinforcement learning can optimize complex control policies, scientific discovery in physical systems fundamentally requires an interpretable chain of reasoning that connects physical evidence to structured control architectures.

By Boai Sun, Wenjin Guo, Zongmin Yu, Liu Yang
arXiv AI
Jun 12

Benchmarking AI Agents for Addressing Scientific Challenges Across Scales

arXiv:2606. 12736v1 Announce Type: new Abstract: AI agents are increasingly being developed to accelerate scientific discovery, yet their practical capabilities in real research settings remain poorly understood.

By Tianyu Liu, Allen Xin Wang, Antonia Panescu, Lisa Xinyi Chen, Wenxin Long, Xinyu Wei, Yueqian Jing, Ziyao Zeng, Jihang Chen, Sihan Jiang, Ziqing Wang, Siyi Gu, Siyu Chen, Xinyang Hu, Haoran Shao, Leqi Xu, Wangjie Zheng, Zhiyuan Cao, Ada Fang, Botao Yu, Kunyang Sun, Rex Ying, Arman Cohan, Qingyu Chen, Lingzhou Xue, Kaize Ding, Yuanqi Du, Wengong Jin, Zhuoran Yang, Marinka Zitnik, James Zou, Hua Xu, Hongyu Zhao
arXiv AI
Aug 13

Apodex Discovery: Reality Benchmarks and Environments for Evaluating and Building Discoverative Artificial Intelligence

arXiv:2608. 11341v1 Announce Type: new Abstract: Apollo did not reach the Moon merely because its engineers could solve difficult equations.

By Brian Wang, Bin Feng, Xiaoman Pan, Chenyang An, Felix Liu, Tangqi Fang, Gongbo Sun, Lingfeng Shen, Ning Wang, Handuo Zhang, Feng Chen, Fuchao Yang, Xiang Wang, Jiacheng Lin, Siting Li, Zixuan Liu, Chi Han, Zhenhailong Wang, Kunlun Zhu, Lawrence Zhao, Yueqi Guo, Kailong Wen, Feng Xing, Yiling Guo, Lidong Bing, David Tan, Bo An, Heng Ji, Sheng Wang