arXiv:2606. 31763v1 Announce Type: new Abstract: Autonomous wet-lab experimentation requires more than plausible protocol text: biological intent, quantitative procedures, device constraints and experimental feedback must remain aligned from protocol and SOP design to code and physical execution.
arXiv:2606. 20120v1 Announce Type: cross Abstract: Biological experiment protocols are written in natural language, whereas automation systems rely on predefined control commands, creating a semantic gap that limits autonomous execution.
arXiv:2606. 03755v1 Announce Type: new Abstract: Autonomous science is moving from demonstration to infrastructure.
arXiv:2605. 07306v2 Announce Type: replace-cross Abstract: Biological laboratory automation can reduce repetitive manual work and improve reproducibility, but reliable embodied execution in wet-lab environments remains challenging.
arXiv:2609. 30971v1 Announce Type: new Abstract: Embodied agents offer a promising route to automating scientific experimentation, yet their progress is constrained by the lack of reliable and systematic evaluation environments.
arXiv:2607. 27690v2 Announce Type: replace-cross Abstract: We introduce LabEvolver, a training-free framework that equips safe and grounded wet-lab agents with episodic memory from execution experience.
arXiv:2607. 23045v1 Announce Type: new Abstract: AI is evaluated through knowledge, reasoning and plan generation, yet scientific agency requires reliable physical action and adaptation to evidence.
LabFactory is a framework that transforms a scientific brief into an executable AI lab, integrating models, knowledge resources, tools, and a controller behind a fixed interface. The builder packages the lab in a metered workspace, and a separate host evaluates the delivered artifact on held‑out inputs, ensuring the system itself is the evaluation target. Across 28 constructions in seven scientific domains, the delivered labs surpassed reference values on all 33 subtests, demonstrating that an AI agent can fully realize a scientific brief into a working, inspectable lab.
WetRobo is a reproducible robot kit designed to enable wet‑lab researchers to delegate tasks to coding agents without teleoperation or neural‑network training. The kit includes a robot arm, essential lab equipment, pre‑recorded teleoperation demos, and a skill file, allowing a coding agent to observe the lab, write, and execute programs using external tools. Experiments with OpenAI Codex on tasks such as lifting a Petri dish lid, removing a bottle cap, and opening an incubator door demonstrated successful performance in two different laboratories, outperforming a fine‑tuned vision‑language‑action policy that failed to transfer.
arXiv:2606. 13578v1 Announce Type: cross Abstract: Scientific laboratories increasingly rely on AI systems to reason about experiments, but the physical act of doing science remains largely outside their reach.
arXiv:2606. 11150v1 Announce Type: new Abstract: Large language models (LLMs) are rapidly acquiring capabilities relevant to biological research, from literature synthesis to interpretation of experimental data.
arXiv:2607. 15620v1 Announce Type: cross Abstract: Self-driving laboratories increasingly rely on low-cost liquid handlers such as the Opentrons OT-2, which ship without the pressure-based aspiration monitoring of Hamilton or Tecan systems and are typically run open-loop.
MOOSEnger is a simulation‑aware AI agent framework designed for the MOOSE ecosystem, integrating an interchangeable reasoning model with domain knowledge, revised simulation artifacts, MOOSE‑specific validation, and executable solver feedback. Its generate‑check‑repair‑run workflow uses MOOSE knowledge retrieval, HIT‑aware parsing, syntax metadata, diagnostics, and revision‑controlled authoring to bind evidence to each input revision and guide bounded repair before acceptance. Across 200 prompts, MOOSEnger raises executable success from 5% to 89.5% with GPT‑5.2 and from 0% to 76.5% with Gemma 4 31B, and a ten‑case benchmark shows all generated inputs meet semantic alignment, with eight also meeting numerical‑accuracy criteria.