MMTClinic is a new benchmark that tests large language models on complex reasoning and question‑answering tasks involving clinical time‑series data. It combines text, medical images, and multivariate physiological signals to create 30,000 QA pairs—including 15,000 multiple‑choice and 15,000 open‑ended questions—in five languages (English, Hindi, Bengali, Marathi, and Tamil). The benchmark covers mortality prediction, heart‑rate forecasting, and SOFA score estimation, and evaluates 13 state‑of‑the‑art LLMs across zero‑shot, few‑shot, and chain‑of‑thought settings, revealing significant performance gaps across tasks, languages, and modalities.
By Sourav Malakar, Harshit Nigam, Akash Ghosh, Sriparna Saha, Amlan Chakrabarti, Saptarsi Goswami, Priti Singh
arXiv:2609.13457v1 Announce Type: new
Abstract: Timeseries multimodal large language models (TS-MLLMs) have recently begun leveraging the reasoning capabilities of large language models (LLMs) for qu...
By Sudarshan Regmi, Arvind Pillai, Yu Yvonne Wu, Yuliang Chen, Bibek Panthi, Tess Z. Griffin, Michael V. Heinz, Lisa Marsch, Nicholas C. Jacobson, Andrew Campbell
arXiv:2609.06976v1 Announce Type: new
Abstract: As medical wearables become integrated into daily chronic disease care, effectively interpreting longitudinal monitoring data is essential for patients...
By Yuchen Niu, Yanan Ma, Srinivasan Nandakumar, Maolin Chen, Viktor Schlegel, Kexin Wei, Ling Cheng, Anna Bird, Anil Anthony Bharath, Siew-Kei Lam
arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).
By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li
BALMS is a benchmark for evaluating large language model (LLM) agents that analyze longitudinal wearable data to predict mental‑health wellbeing scores and generate evidence‑grounded rationales. It covers three real‑world datasets, two task families (score prediction and rationale generation), and tests five LLM backbones across open‑ and closed‑source paradigms. The study finds that zero‑shot agents rarely beat a simple mean baseline, and while chain‑of‑thought prompting helps reasoning, it does not ensure temporal grounding or numerical accuracy.
By Yu Yvonne Wu, Arvind Pillai, Yuliang Chen, Yuwei Zhang, Sudarshan Regmi, Tess Z. Griffin, Michael V. Heinz, Lisa A. Marsch, Nicholas C. Jacobson, Andrew Campbell
arXiv:2601.13880v2 Announce Type: replace
Abstract: Personalized lifestyle health analysis requires long-horizon, multi-dimensional reasoning over heterogeneous lifestyle signals, and recent advances...
By Ye Tian, Zihao Wang, Onat Gungor, Xiaoran Fan, Tajana Rosing
arXiv:2607. 25947v1 Announce Type: new Abstract: Question answering (QA) over irregular clinical time series (ICTS) plays a pivotal role in a wide range of healthcare applications.
By Frank Nie, Ethan B Liu, Yuan Zhu, Wei Fan, Jindong Han
WearableQA is a new benchmark that tests AI systems on health reasoning using real-world wearable data from 200 users, each with up to 500 days of daily measurements. It contains 4,084 ten‑option multiple‑choice questions derived from wearable time series, blood biomarkers, and demographics, and is organized into 16 question types that distinguish data‑driven computation from physiological interpretation and single‑signal from cross‑signal reasoning. Evaluation of 14 large language models shows wide performance gaps, indicating that the benchmark remains challenging and useful for diagnosing model capabilities.
By Ji Soo Lee, Xilun Chen, Pierce Chuang, Ashish Shenoy, Jason Wei, Dohwan Ko, Hyunwoo J. Kim, Benoit Corda
arXiv:2609.22262v1 Announce Type: cross
Abstract: Medical time series (MedTS), including electrocardiograms (ECG), electroencephalograms (EEG), photoplethysmography (PPG), and vital-sign recordings,...
By Yu Han, Cigdem Beyan, Xiang Zhang, Xiaofeng Liu, Nan Liu, Jimeng Sun, Shenda Hong, Cheng Ding, Vittorio Murino
arXiv:2510. 17532v2 Announce Type: replace-cross Abstract: Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data.
By Raghu Vamshi Hemadri, Geetha Krishna Guruju, Kristi Topollai, Anna Ewa Choromanska
arXiv:2609.24480v1 Announce Type: cross
Abstract: Deploying Large Language Models (LLMs) in healthcare requires robust performance across two complementary dimensions - diagnostic reasoning: the conv...
By Kalash Shah, Kunal Singh, Snehan J, Shreyas Singh
arXiv:2606. 12481v1 Announce Type: cross Abstract: Large language models (LLMs) have demonstrated strong reasoning and instruction-following capabilities, making them potentially powerful tools for time-series analysis.
By Jaeho Kim, Changhun Oh, Seokhyun Lee, Irina Rish, Changhee Lee