arXiv Machine Learning

HealthLoopQA: A Context-Aware Question Answering Benchmark for Interpreting Wearable Monitoring Data in Diabetes Care

arXiv Computation and Language
Sep 7

WearableQA: A Benchmark for Health Reasoning over Real-World Wearable Data

WearableQA is a new benchmark that tests AI systems on health reasoning using real-world wearable data from 200 users, each with up to 500 days of daily measurements. It contains 4,084 ten‑option multiple‑choice questions derived from wearable time series, blood biomarkers, and demographics, and is organized into 16 question types that distinguish data‑driven computation from physiological interpretation and single‑signal from cross‑signal reasoning. Evaluation of 14 large language models shows wide performance gaps, indicating that the benchmark remains challenging and useful for diagnosing model capabilities.

By Ji Soo Lee, Xilun Chen, Pierce Chuang, Ashish Shenoy, Jason Wei, Dohwan Ko, Hyunwoo J. Kim, Benoit Corda
arXiv Computation and Language
Aug 28

BALMS: Benchmarking Agentic LLMs for Longitudinal Mental Health Sensing

BALMS is a benchmark for evaluating large language model (LLM) agents that analyze longitudinal wearable data to predict mental‑health wellbeing scores and generate evidence‑grounded rationales. It covers three real‑world datasets, two task families (score prediction and rationale generation), and tests five LLM backbones across open‑ and closed‑source paradigms. The study finds that zero‑shot agents rarely beat a simple mean baseline, and while chain‑of‑thought prompting helps reasoning, it does not ensure temporal grounding or numerical accuracy.

By Yu Yvonne Wu, Arvind Pillai, Yuliang Chen, Yuwei Zhang, Sudarshan Regmi, Tess Z. Griffin, Michael V. Heinz, Lisa A. Marsch, Nicholas C. Jacobson, Andrew Campbell
arXiv AI
Jun 19

VitalAgent: A Tool-Augmented Agent for Reactive and Proactive Physiological Monitoring over Wearable Health Data

arXiv:2605. 29483v2 Announce Type: replace Abstract: Wearable devices enable continuous monitoring of physiological signals such as ECG and PPG, but existing mHealth systems are largely limited to task-specific prediction pipelines or reactive question answering over static summaries.

By Di Zhu, Yu Yvonne Wu, Hong Jia, Aaqib Saeed, Vassilis Kostakos, Ting Dang
arXiv AI
Sep 7

MMTClinic: Multimodal, Multilingual Time Series Question Answering and Reasoning Benchmark for Clinical Domain

MMTClinic is a new benchmark that tests large language models on complex reasoning and question‑answering tasks involving clinical time‑series data. It combines text, medical images, and multivariate physiological signals to create 30,000 QA pairs—including 15,000 multiple‑choice and 15,000 open‑ended questions—in five languages (English, Hindi, Bengali, Marathi, and Tamil). The benchmark covers mortality prediction, heart‑rate forecasting, and SOFA score estimation, and evaluates 13 state‑of‑the‑art LLMs across zero‑shot, few‑shot, and chain‑of‑thought settings, revealing significant performance gaps across tasks, languages, and modalities.

By Sourav Malakar, Harshit Nigam, Akash Ghosh, Sriparna Saha, Amlan Chakrabarti, Saptarsi Goswami, Priti Singh
arXiv Computation and Language
Sep 1

CARE: Privacy-Compliant Agentic Reasoning with Evidence Discordance

The paper introduces MIMIC-DOS, a dataset derived from MIMIC-IV that focuses on ICU cases where patient symptoms and medical signs are discordant. It presents CARE, a privacy‑compliant multi‑stage agentic reasoning framework that uses a proprietary LLM to generate structured categories and transitions, while a local LLM performs evidence acquisition and decision‑making. In retrospective evaluations on MIMIC‑DOS, CARE outperforms other LLMs and agentic workflows, demonstrating stronger handling of conflicting clinical evidence while preserving patient privacy.

By Haochen Liu, Weien Li, Rui Song, Zeyu Li, Chun Jason Xue, Xiao-Yang Liu, Sam Nallaperuma-Herzberg, Xue Liu, Ye Yuan
arXiv Machine Learning
Jul 17

Addressing Benchmarking Gaps in Large Language Models for Health and Medicine with Dynamic Red-Teaming

arXiv:2508. 00923v3 Announce Type: replace Abstract: Large language models (LLMs) are increasingly used to answer health-related questions and support healthcare workflows, yet evidence for their safety still relies heavily on static benchmarks that can rapidly become obsolete or be optimized against.

By Jiazhen Pan (Cherise), Bailiang Jian (Cherise), Paul Hager (Cherise), Yundi Zhang (Cherise), Che Liu (Cherise), Friederike Jungmann (Cherise), Hongwei Bran Li (Cherise), Julian Canisius (Cherise), Chenyu You (Cherise), Junde Wu (Cherise), Jiayuan Zhu (Cherise), Fenglin Liu (Cherise), Yuyuan Liu (Cherise), Niklas Bubeck (Cherise), Moritz Knolle (Cherise), Chen (Cherise), Chen (Cherise), Christian Wachinger, Zhenyu Gong, Cheng Ouyang, Georgios Kaissis, Benedikt Wiestler, Daniel Rueckert
arXiv AI
Jun 3

ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).

By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li